Functional requirements of protein kinases and phosphatases in the development of the Drosophila melanogaster wing

Autor: Cristina M Ostalé, Nuria Esteban, Ana López-Varea, Jose F de Celis

Publikováno v: G3: Genes, Genomes, Genetics, Vol 11, Iss 12 (2021)

AbstractProtein kinases and phosphatases constitute a large family of conserved enzymes that control a variety of biological processes by regulating the phosphorylation state of target proteins. They play fundamental regulatory roles during cell cycl

Externí odkaz: https://doaj.org/article/3963b1d96c0646228f384e27ece4d9a9

RNAi screen in the Drosophila wing of genes encoding proteins related to cytoskeleton organization and cell division

Autor: Jose de Celis, Cristina M. Ostalé, Patricia Vega-Cuesta, Tamara González, Ana López-Varea

Publikováno v: Developmental Biology. 498:61-76

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8180590f60e9fdb0b9b41f81015c81a
https://doi.org/10.1016/j.ydbio.2023.03.010

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Autor: Cristina M. Ostalé, Mercedes Martín, Cristina Molnar, Nuria Esteban, Covadonga F Hevia, María F. Organista, Ana López-Varea, Patricia Vega-Cuesta, Jose F. de Celis, Joaquín Culí, Ana Ruiz-Gómez, Jesús de Celis

Publikováno v: G3: Genes, Genomes, Genetics, Vol 11, Iss 12 (2021)
G3: Genes|Genomes|Genetics
Biblos-e Archivo. Repositorio Institucional de la UAM
instname

The Drosophila genome contains approximately 14,000 protein-coding genes encoding all the necessary information to sustain cellular physiology, tissue organization, organism development, and behavior. In this manuscript, we describe in some detail th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a885f6353a20e56244ce2717f3eb19dc
https://academic.oup.com/g3journal/article-lookup/doi/10.1093/g3journal/jkab349

Drosophila Imaginal Discs as a Playground for Genetic Analysis: Concepts, Techniques and Expectations for Biomedical Research

Autor: Mireya Ruiz-Losada, Patricia Vega, Carlos Estella, Jose F. de Celis, Ana Ruiz-Gómez, Cristina M. Ostalé

Publikováno v: Drosophila melanogaster-Model for Recent Advances in Genetics and Therapeutics

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3617a24ef119b8e45ff3ee6aec4a6e47
http://www.intechopen.com/articles/show/title/drosophila-imaginal-discs-as-a-playground-for-genetic-analysis-concepts-techniques-and-expectations-

DUSP10 Is a Regulator of YAP1 Activity Promoting Cell Proliferation and Colorectal Cancer Progression

Autor: Marta Jiménez-Martínez, Lukas J. A. C. Hawinkels, Ricardo López-Pérez, Lennart R A van der Burg, Cristina M. Ostalé, James C. H. Hardwick, Konstantinos Stamatakis, Javier Galán-Martínez, Manuel Fresno

Publikováno v: Cancers
Volume 11
Issue 11
Cancers, 11(11)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cancers, Vol 11, Iss 11, p 1767 (2019)

Cell contact inhibition (CCI) is deregulated in cancer. Colorectal cancer (CRC) is the third most commonly diagnosed cancer worldwide. We found that dual-specificity phosphatase 10 (DUSP10) is involved in CRC. DUSP10 overexpression increased the grow

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bea56198ca457bf738bbed50483ed40
https://doi.org/10.3390/cancers11111767