Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Cristina Lopez Lopez"'
Autor:
Angelika Caputo, Amy Racine, Ines Paule, Pierre N. Tariot, Jessica B. Langbaum, Neva Coello, Marie-Emmanuelle Riviere, J. Michael Ryan, Cristina Lopez Lopez, Ana Graf, for the National Alzheimer’s Coordinating Center, for the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-19 (2023)
Abstract Background There is a critical need for novel primary endpoints designed to detect early and subtle changes in cognition in clinical trials targeting the asymptomatic (preclinical) phase of Alzheimer’s disease (AD). The Alzheimer’s Preve
Externí odkaz:
https://doaj.org/article/b6f0a45931354595ad372db4809d8620
Autor:
Lanfranco Pellesi, Mohammad Al-Mahdi Al-Karagholi, Roberto De Icco, Basit Ali Chaudhry, Cristina Lopez Lopez, Josefin Snellman, Jens Hannibal, Faisal Mohammad Amin, Messoud Ashina
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
IntroductionThe activation of perivascular fibers and the consequent release of vasoactive peptides, including the vasoactive intestinal polypeptide (VIP), play a role in migraine pathogenesis. A 2-h infusion of VIP provoked migraine, but the mechani
Externí odkaz:
https://doaj.org/article/56790fb9891c42f7908c2f35e27ef943
Autor:
Jessica B. Langbaum, Noel N. Ellison, Angelika Caputo, Ronald G. Thomas, Carolyn Langlois, Marie-Emmanuelle Riviere, Ana Graf, Cristina Lopez Lopez, Eric M. Reiman, Pierre N. Tariot, Suzanne B. Hendrix
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-11 (2020)
Abstract Background There is growing interest in identifying sensitive composite cognitive tests to serve as primary endpoints in preclinical Alzheimer’s disease (AD) treatment trials. We reported previously a composite cognitive test score sensiti
Externí odkaz:
https://doaj.org/article/e7c88447f10341739672d2101169bc6e
Autor:
Ulf Neumann, Mike Ufer, Laura H Jacobson, Marie‐Laure Rouzade‐Dominguez, Gunilla Huledal, Carine Kolly, Rainer M Lüönd, Rainer Machauer, Siem J Veenstra, Konstanze Hurth, Heinrich Rueeger, Marina Tintelnot‐Blomley, Matthias Staufenbiel, Derya R Shimshek, Ludovic Perrot, Wilfried Frieauff, Valerie Dubost, Hilmar Schiller, Barbara Vogg, Karen Beltz, Alexandre Avrameas, Sandrine Kretz, Nicole Pezous, Jean‐Michel Rondeau, Nicolau Beckmann, Andreas Hartmann, Stefan Vormfelde, Olivier J David, Bruno Galli, Rita Ramos, Ana Graf, Cristina Lopez Lopez
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 11, Pp n/a-n/a (2018)
Abstract The beta‐site amyloid precursor protein cleaving enzyme‐1 (BACE‐1) initiates the generation of amyloid‐β (Aβ), and the amyloid cascade leading to amyloid plaque deposition, neurodegeneration, and dementia in Alzheimer's disease (AD
Externí odkaz:
https://doaj.org/article/48fbf5e81f1a4f18ae40665093c63175
Autor:
Angelika Caputo, Amy Racine, Ines Paule, Pierre N. Tariot, Jessica B. Langbaum, Neva Coello, Marie-Emmanuelle Riviere, J. Michael Ryan, Cristina Lopez Lopez, Ana Graf
Background: There is a critical need for novel primary endpoints designed to detect early and subtle changes in cognition in clinical trials targeting the asymptomatic (preclinical) phase of Alzheimer’s disease (AD). The Alzheimer’s Prevention In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61a9b9d0026190972bee5101a1849806
https://doi.org/10.21203/rs.3.rs-2226991/v1
https://doi.org/10.21203/rs.3.rs-2226991/v1
Autor:
Christopher Kjaer Cullum, Thien Phu Do, Messoud Ashina, Lars Bendtsen, Sarah Sonja Hugger, Afrim Iljazi, Julia Gusatovic, Josefin Snellman, Cristina Lopez-Lopez, Håkan Ashina, Faisal Mohammad Amin
Publikováno v:
Cullum, C K, Do, T P, Ashina, M, Bendtsen, L, Hugger, S S, Iljazi, A, Gusatovic, J, Snellman, J, Lopez-Lopez, C, Ashina, H & Amin, F M 2022, ' Real-world long-term efficacy and safety of erenumab in adults with chronic migraine : a 52-week, single-center, prospective, observational study ', Journal of Headache and Pain, vol. 23, no. 1, 61 . https://doi.org/10.1186/s10194-022-01433-9
Background Clinical trials have shown that erenumab is effective and well-tolerated for the preventive treatment of chronic migraine. To extend the results from clinical trials, we assessed the real-world efficacy and safety of erenumab in patients w
Autor:
Matias Ferraris, R. G. Shah, Mark A Cheadle, Juanzhi Fang, Stephanie Korrer, Cristina Lopez-Lopez, Jonathan C Johnson
Publikováno v:
Advances in Therapy. 38:2921-2934
This retrospective analysis aimed to characterize patients with migraine initiating erenumab and the shifting or trend of patient characteristics over time in a real-world setting. Adult patients with at least one erenumab written prescription/admini
Autor:
Faisal Mohammad Amin, Josefin Snellman, Mohammad Al-Mahdi Al-Karagholi, Cristina Lopez Lopez, Jens Hannibal, Lanfranco Pellesi, Messoud Ashina, Basit Chaudhry
Publikováno v:
Cephalalgia. 40:1212-1223
Background In recent years, vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptides (PACAPs) have gained special interest in headache science. VIP and PACAPs (two isoforms, PACAP27 and PACAP38) are related in struc
Autor:
Marie-Emmanuelle Riviere, Carolyn Langlois, Ana Graf, Cristina Lopez Lopez, Eric M. Reiman, Suzanne Hendrix, Pierre N. Tariot, Ronald G. Thomas, Angelika Caputo, Noel Ellison, Jessica B. Langbaum
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-11 (2020)
Alzheimer's Research & Therapy
Alzheimer's Research & Therapy
Background There is growing interest in identifying sensitive composite cognitive tests to serve as primary endpoints in preclinical Alzheimer’s disease (AD) treatment trials. We reported previously a composite cognitive test score sensitive to tra
Autor:
Hande Coskun, Roberto De Icco, Cristina Lopez-Lopez, Josefin Snellman, Lanfranco Pellesi, Messoud Ashina, Faisal Mohammad Amin, Mohammad Al-Mahdi Al-Karagholi, Fatima Azzahra Elbahi, Jens Hannibal
Publikováno v:
Pellesi, L, Al-Karagholi, M A M, De Icco, R, Coskun, H, Elbahi, F A, Lopez-Lopez, C, Snellman, J, Hannibal, J, Amin, F M & Ashina, M 2021, ' Effect of Vasoactive Intestinal Polypeptide on Development of Migraine Headaches : A Randomized Clinical Trial ', JAMA network open, vol. 4, no. 8, e2118543 . https://doi.org/10.1001/jamanetworkopen.2021.18543
Importance: Vasoactive intestinal polypeptide (VIP) and pituitary adenylate cyclase-activating polypeptides (PACAPs) are structurally and functionally related, yet different in their migraine-inducing properties. It remains unclear whether the lack o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8809ba15a6d494959be956c29ffdc5b9
https://curis.ku.dk/ws/files/284007858/pellesi_2021_oi_210554_1627575050.26329.pdf
https://curis.ku.dk/ws/files/284007858/pellesi_2021_oi_210554_1627575050.26329.pdf