Zobrazeno 1 - 10
of 233
pro vyhledávání: '"Cristina Limatola"'
Autor:
Francesco Marrocco, Elisabetta Falvo, Luciana Mosca, Giada Tisci, Alessandro Arcovito, Alice Reccagni, Cristina Limatola, Roberta Bernardini, Pierpaolo Ceci, Giuseppina D’Alessandro, Gianni Colotti
Publikováno v:
Cell Death and Disease, Vol 15, Iss 4, Pp 1-10 (2024)
Abstract Gliomas are among the most fatal tumors, and the available therapeutic options are very limited. Additionally, the blood-brain barrier (BBB) prevents most drugs from entering the brain. We designed and produced a ferritin-based stimuli-sensi
Externí odkaz:
https://doaj.org/article/6e3bf7316b2d4140a4a9dc60640a5167
Autor:
Maria Rosito, Javeria Maqbool, Alice Reccagni, Ottavia Giampaoli, Fabio Sciubba, Fabrizio Antonangeli, Ferdinando Scavizzi, Marcello Raspa, Federica Cordella, Lucrezia Tondo, Silvia Di Angelantonio, Flavia Trettel, Alfredo Miccheli, Giuseppina D’Alessandro, Cristina Limatola
Publikováno v:
Cell Death and Disease, Vol 15, Iss 3, Pp 1-18 (2024)
Abstract In recent years, several studies described the close relationship between the composition of gut microbiota and brain functions, highlighting the importance of gut-derived metabolites in mediating neuronal and glial cells cross-talk in physi
Externí odkaz:
https://doaj.org/article/08307056e0494d279f826da195a80272
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition characterized by elusive underlying mechanisms. Recent attention has focused on the involvement of astrocytes and microglia in ASD pathology. These glial cells play pivotal role
Externí odkaz:
https://doaj.org/article/b2e69c9bb3d44627b25390a2a0010c3a
Autor:
Stefano Garofalo, Germana Cocozza, Alessandro Mormino, Giovanni Bernardini, Eleonora Russo, Donald Ielpo, Diego Andolina, Rossella Ventura, Katiuscia Martinello, Massimiliano Renzi, Sergio Fucile, Mattia Laffranchi, Eva Piano Mortari, Rita Carsetti, Giuseppe Sciumè, Silvano Sozzani, Angela Santoni, Marie-Eve Tremblay, Richard M. Ransohoff, Cristina Limatola
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract The mechanisms of communication between the brain and the immune cells are still largely unclear. Here, we characterize the populations of resident natural killer (NK) cells and innate lymphoid cells (ILC) 1 in the meningeal dura layer of ad
Externí odkaz:
https://doaj.org/article/0211a315673a47ed8fe4e14ffd46fcd7
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2024)
Astrocytes are highly plastic cells whose activity is essential to maintain the cerebral homeostasis, regulating synaptogenesis and synaptic transmission, vascular and metabolic functions, ions, neuro- and gliotransmitters concentrations. In patholog
Externí odkaz:
https://doaj.org/article/b9689fc9524848eca1d0ba73f5b0f950
Autor:
Patrizia Ratano, Germana Cocozza, Cecilia Pinchera, Ludovica Maria Busdraghi, Iva Cantando, Katiuscia Martinello, Mariarosaria Scioli, Maria Rosito, Paola Bezzi, Sergio Fucile, Heike Wulff, Cristina Limatola, Giuseppina D’Alessandro
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2024)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with no effective therapy, causing progressive loss of motor neurons in the spinal cord, brainstem, and motor cortex. Regardless of its genetic or sporadic origin, there is curr
Externí odkaz:
https://doaj.org/article/7b0c83b8d0b3491eaf2f6c242eacace9
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
In recent years, biomedical research efforts aimed to unravel the mechanisms involved in motor neuron death that occurs in amyotrophic lateral sclerosis (ALS). While the main causes of disease progression were first sought in the motor neurons, more
Externí odkaz:
https://doaj.org/article/04dc83b3b7d34f7a8c96553e4003a48d
Autor:
Francesco Marrocco, Mary Delli Carpini, Stefano Garofalo, Ottavia Giampaoli, Eleonora De Felice, Maria Amalia Di Castro, Laura Maggi, Ferdinando Scavizzi, Marcello Raspa, Federico Marini, Alberta Tomassini, Roberta Nicolosi, Carolina Cason, Flavia Trettel, Alfredo Miccheli, Valerio Iebba, Giuseppina D’Alessandro, Cristina Limatola
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Mice exposed to environmental enrichment for 5 weeks display distinct microbiota composition and behavioral and metabolic profiles compared to mice exposed to a standard environment. Mice treated with a mixture of short-chain fatty acids that are pro
Externí odkaz:
https://doaj.org/article/c9b5b85ca13a4e698b642e6cbfd025f2
Autor:
Francesca Massenzio, Marco Cambiaghi, Federica Marchiotto, Diana Boriero, Cristina Limatola, Giuseppina D’Alessandro, Mario Buffelli
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Tumor associated macrophages (TAMs) are the mostprevalent cells recruited in the tumor microenvironment (TME). Once recruited, TAMs acquire a pro-tumor phenotype characterized by a typical morphology: ameboid in the tumor core and with larger soma an
Externí odkaz:
https://doaj.org/article/8418faa956394237a2923feb2680addf
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Microglial cells play pleiotropic homeostatic activities in the brain, during development and in adulthood. Microglia regulate synaptic activity and maturation, and continuously patrol brain parenchyma monitoring for and reacting to eventual alterati
Externí odkaz:
https://doaj.org/article/71d2424aeb9945fc9be67b9fa342eba3