Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Cristina Leoni"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Mast cells are central players in allergy and asthma, and their dysregulated responses lead to reduced quality of life and life-threatening conditions such as anaphylaxis. The RNA modification N6-methyladenosine (m6A) has a prominent impact
Externí odkaz:
https://doaj.org/article/8b46bbf57e18487bb03f20a2df535088
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0247232 (2021)
The appropriate regulation of T lymphocyte functions is key to achieve protective immune responses, while at the same time limiting the risks of tissue damage and chronic inflammation. Deciphering the mechanisms underpinning T cell responses in human
Externí odkaz:
https://doaj.org/article/a97c27abf17e43c882e82321c17f3d3c
Autor:
Sara Montagner, Cristina Leoni, Stefan Emming, Giulia Della Chiara, Chiara Balestrieri, Iros Barozzi, Viviana Piccolo, Susan Togher, Myunggon Ko, Anjana Rao, Gioacchino Natoli, Silvia Monticelli
Publikováno v:
Cell Reports, Vol 15, Iss 7, Pp 1566-1579 (2016)
Summary: Dioxygenases of the TET family impact genome functions by converting 5-methylcytosine (5mC) in DNA to 5-hydroxymethylcytosine (5hmC). Here, we identified TET2 as a crucial regulator of mast cell differentiation and proliferation. In the abse
Externí odkaz:
https://doaj.org/article/40b26c13096e42519aa36b21a13ac9d2
Autor:
Silvia Monticelli, Cristina Leoni
Publikováno v:
F1000Research, Vol 6 (2017)
Mast cells are tissue-resident, innate immune cells present in most tissues of the body and are important effector and immunomodulatory cells. Differentiated mast cells typically are characterized by the surface expression of the receptors KIT and Fc
Externí odkaz:
https://doaj.org/article/85d556d7a34f4779b584a3ed8141c799
Publikováno v:
Swiss Medical Weekly, Vol 145, Iss 4344 (2015)
The risk of developing autoimmune diseases depends on both genetic and environmental factors, with epigenetic mechanisms of regulation potentially translating environmental cues into stable modifications in gene expression. Such stable memory of a fu
Externí odkaz:
https://doaj.org/article/6af9c2f65f28495f82816146ce786cc4
Autor:
Sara Montagner, Cristina Leoni, Stefan Emming, Giulia Della Chiara, Chiara Balestrieri, Iros Barozzi, Viviana Piccolo, Susan Togher, Myunggon Ko, Anjana Rao, Gioacchino Natoli, Silvia Monticelli
Publikováno v:
Cell Reports, Vol 20, Iss 7, p 1744 (2017)
Externí odkaz:
https://doaj.org/article/facce51c002d4c5c9b88a837aba8c205
Autor:
Taku Ito-Kureha, Cristina Leoni, Kayla Borland, Giulia Cantini, Marian Bataclan, Rebecca N. Metzger, Gregor Ammann, Anne B. Krug, Annalisa Marsico, Stefanie Kaiser, Stefan Canzar, Stefan Feske, Silvia Monticelli, Julian König, Vigo Heissmeyer
Publikováno v:
Nat. Immunol. 23, 1208-1221 (2022)
T cell antigen-receptor (TCR) signaling controls the development, activation and survival of T cells by involving several layers and numerous mechanisms of gene regulation. N6-methyladenosine (m6A) is the most prevalent messenger RNA modification aff
Autor:
Santiago F. Gonzalez, Francesco Bertoni, Ron N. Apte, Silvia Monticelli, Elena Voronov, Lorenzo Mortara, Antonino Bruno, Robert E. Hunger, Fausto Sessa, Anna Maria Chiaravalli, Ivo Kwee, Aner Ottolenghi, Marina Bersudsky, S. Morteza Seyed Jafari, Diego Morone, Alberto J. Arribas, Andrea Rinaldi, Murodzhon Akhmedov, Cristina Leoni, Daniel Molina Romero, Irene Latino, Giulio Sartori, Luciano Cascione, Joy Bordini, Tommaso Virgilio
Supplementary Data from Subcapsular Sinus Macrophages Promote Melanoma Metastasis to the Sentinel Lymph Nodes via an IL1α–STAT3 Axis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64b119f8cdc0cfa5ec74515efd80036f
https://doi.org/10.1158/2326-6066.22546067.v1
https://doi.org/10.1158/2326-6066.22546067.v1
Autor:
Santiago F. Gonzalez, Francesco Bertoni, Ron N. Apte, Silvia Monticelli, Elena Voronov, Lorenzo Mortara, Antonino Bruno, Robert E. Hunger, Fausto Sessa, Anna Maria Chiaravalli, Ivo Kwee, Aner Ottolenghi, Marina Bersudsky, S. Morteza Seyed Jafari, Diego Morone, Alberto J. Arribas, Andrea Rinaldi, Murodzhon Akhmedov, Cristina Leoni, Daniel Molina Romero, Irene Latino, Giulio Sartori, Luciano Cascione, Joy Bordini, Tommaso Virgilio
During melanoma metastasis, tumor cells originating in the skin migrate via lymphatic vessels to the sentinel lymph node (sLN). This process facilitates tumor cell spread across the body. Here, we characterized the innate inflammatory response to mel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f9251053f9675706017bf20c384bc43
https://doi.org/10.1158/2326-6066.c.6551081
https://doi.org/10.1158/2326-6066.c.6551081
Autor:
Santiago F. Gonzalez, Francesco Bertoni, Ron N. Apte, Silvia Monticelli, Elena Voronov, Lorenzo Mortara, Antonino Bruno, Robert E. Hunger, Fausto Sessa, Anna Maria Chiaravalli, Ivo Kwee, Aner Ottolenghi, Marina Bersudsky, S. Morteza Seyed Jafari, Diego Morone, Alberto J. Arribas, Andrea Rinaldi, Murodzhon Akhmedov, Cristina Leoni, Daniel Molina Romero, Irene Latino, Giulio Sartori, Luciano Cascione, Joy Bordini, Tommaso Virgilio
Supplementary Figure from Subcapsular Sinus Macrophages Promote Melanoma Metastasis to the Sentinel Lymph Nodes via an IL1α–STAT3 Axis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d75321c5f97e9057a8c71920ebda9f3
https://doi.org/10.1158/2326-6066.22546061
https://doi.org/10.1158/2326-6066.22546061