Zobrazeno 1 - 10
of 240
pro vyhledávání: '"Cristina Legido-Quigley"'
Autor:
Peter Rossing, Simone Theilade, Christian Stevns Hansen, Marie Frimodt-Moller, Viktor Rotbain Curovic, Tine W Hansen, Cristina Legido-Quigley, Nete Tofte, Tarunveer S Ahluwalia, Ismo Matias Mattila, Brede A Sørland, Siddhi Y Jain, Karolina Sulek, Kajetan Trost, Signe Abitz Winther
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 12, Iss 2 (2024)
Introduction Diabetic retinopathy (DR), diabetic kidney disease (DKD) and distal symmetric polyneuropathy (DSPN) share common pathophysiology and pose an additive risk of early mortality.Research design and methods In adults with type 1 diabetes, 49
Externí odkaz:
https://doaj.org/article/1af062286c6c4c5eac1dbe7151d7f537
Autor:
Stine Johansen, Simon Langkjær, Ditlev Nytoft Rasmussen, Mads Israelsen, Nikolaj Torp, Katrine Lindvig, Maria Kjærgaard, Johanne Kragh Hansen, Camilla Dalby Hansen, Katrine Thorhauge, Peter Andersen, Sönke Detlefsen, Helene Bæk Juel, Ulrik Stenz Justesen, Torben Hansen, Aleksander Krag, Maja Thiele, Ema Anastasiadou, Manimozhian Arumugam, Peer Bork, Jenny Presto, Hans Israelsen, Morten Karsdal, Cristina Legido-Quigley, Hans Olav Melberg, Jonel Trebicka, Mathias Mann, Jelle Matthijnssens
Publikováno v:
JHEP Reports, Vol 6, Iss 4, Pp 101016- (2024)
Background & Aims: Infections are frequent in patients with cirrhosis and worsen prognosis. We evaluated the incidence of infections and their impact on decompensation and death in patients with early alcohol-related liver disease (ALD) during long-t
Externí odkaz:
https://doaj.org/article/0139fe8a16594c2aabc3b535edca94a1
Autor:
Alexander Neumann, Olena Ohlei, Fahri Küçükali, Isabelle J. Bos, Jigyasha Timsina, Stephanie Vos, Dmitry Prokopenko, Betty M. Tijms, Ulf Andreasson, Kaj Blennow, Rik Vandenberghe, Philip Scheltens, Charlotte E. Teunissen, Sebastiaan Engelborghs, Giovanni B. Frisoni, Oliver Blin, Jill C. Richardson, Régis Bordet, Alberto Lleó, Daniel Alcolea, Julius Popp, Thomas W. Marsh, Priyanka Gorijala, Christopher Clark, Gwendoline Peyratout, Pablo Martinez-Lage, Mikel Tainta, Richard J. B. Dobson, Cristina Legido-Quigley, Christine Van Broeckhoven, Rudolph E. Tanzi, Mara ten Kate, Christina M. Lill, Frederik Barkhof, Carlos Cruchaga, Simon Lovestone, Johannes Streffer, Henrik Zetterberg, Pieter Jelle Visser, Kristel Sleegers, Lars Bertram, EMIF-AD & ADNI study group
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-23 (2023)
Abstract Background Genome-wide association studies (GWAS) of Alzheimer’s disease (AD) have identified several risk loci, but many remain unknown. Cerebrospinal fluid (CSF) biomarkers may aid in gene discovery and we previously demonstrated that si
Externí odkaz:
https://doaj.org/article/f26d48a8fac447809738ca263de2f029
Autor:
Asger Wretlind, Viktor Rotbain Curovic, Andressa de Zawadzki, Tommi Suvitaival, Jin Xu, Emilie Hein Zobel, Bernt Johan von Scholten, Rasmus Sejersten Ripa, Andreas Kjaer, Tine Willum Hansen, Tina Vilsbøll, Henrik Vestergaard, Peter Rossing, Cristina Legido-Quigley
Publikováno v:
Lipids in Health and Disease, Vol 22, Iss 1, Pp 1-12 (2023)
Abstract Background Specific ceramides have been identified as risk markers for cardiovascular disease (CVD) years before onset of disease. Treatment with the glucagon-like peptide-1 receptor agonist (GLP-1RA) liraglutide has been shown to induce ben
Externí odkaz:
https://doaj.org/article/81dad782fa1040f5abe1e046c103c5d3
Autor:
Marta Lombardi, Federica Scaroni, Martina Gabrielli, Stefano Raffaele, Elisabetta Bonfanti, Fabia Filipello, Paola Giussani, Silvia Picciolini, Nicole Kerlero de Rosbo, Antonio Uccelli, Maria Teresa Golia, Giulia D’Arrigo, Tiziana Rubino, Kourosh Hooshmand, Cristina Legido-Quigley, Chiara Fenoglio, Alice Gualerzi, Marta Fumagalli, Claudia Verderio
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionMicroglia and macrophages can influence the evolution of myelin lesions through the production of extracellular vesicles (EVs). While microglial EVs promote in vitro differentiation of oligodendrocyte precursor cells (OPCs), whether EVs d
Externí odkaz:
https://doaj.org/article/39fef6c0871144b08901d50ca8ed0575
Autor:
Rebecca E. Green, Jodie Lord, Marzia A. Scelsi, Jin Xu, Andrew Wong, Sarah Naomi-James, Alex Handy, Lachlan Gilchrist, Dylan M. Williams, Thomas D. Parker, Christopher A. Lane, Ian B. Malone, David M. Cash, Carole H. Sudre, William Coath, David L. Thomas, Sarah Keuss, Richard Dobson, Cristina Legido-Quigley, Nick C. Fox, Jonathan M. Schott, Marcus Richards, Petroula Proitsi, The Insight 46 study team
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-13 (2023)
Abstract Background Identifying blood-based signatures of brain health and preclinical pathology may offer insights into early disease mechanisms and highlight avenues for intervention. Here, we systematically profiled associations between blood meta
Externí odkaz:
https://doaj.org/article/f5a5b80764c34bc1b3fd5049c6dcb527
Autor:
Luis F. Ferreira-Divino, Tommi Suvitaival, Viktor Rotbain Curovic, Nete Tofte, Kajetan Trošt, Ismo M. Mattila, Simone Theilade, Signe A. Winther, Tine W. Hansen, Marie Frimodt-Møller, Cristina Legido-Quigley, Peter Rossing
Publikováno v:
Cardiovascular Diabetology, Vol 21, Iss 1, Pp 1-10 (2022)
Abstract Background Cardiovascular disease remains the leading cause of mortality in individuals with diabetes and improved understanding of its pathophysiology is needed. We investigated the association of a large panel of metabolites and molecular
Externí odkaz:
https://doaj.org/article/389bfe119996400782c26301fc940633
Autor:
Ulrik Pedersen-Bjergaard, Cristina Legido-Quigley, Rui She, Naba Hassan Al-sari, Ismo Matias Mattila, Anne-Sophie Sejling, Jens Pedersen
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 11, Iss 3 (2023)
Introduction Hypoglycemia is a major limiting factor in achieving recommended glycemic targets for people with type 1 diabetes. Exposure to recurrent hypoglycemia results in blunted hormonal counter-regulatory and symptomatic responses to hypoglycemi
Externí odkaz:
https://doaj.org/article/848fbb24fd444d2888841722dfc719f2
Autor:
Jodie Lord, Rebecca Green, Shing Wan Choi, Christopher Hübel, Dag Aarsland, Latha Velayudhan, Pak Sham, Cristina Legido-Quigley, Marcus Richards, Richard Dobson, Petroula Proitsi
Publikováno v:
Biological Psychiatry Global Open Science, Vol 2, Iss 2, Pp 167-179 (2022)
Background: Education and cognition demonstrate consistent inverse associations with Alzheimer’s disease (AD). The biological underpinnings, however, remain unclear. Blood metabolites reflect the end point of biological processes and are accessible
Externí odkaz:
https://doaj.org/article/d7d4f99f2fd1491680c7025a8e715b65
Autor:
Marc Clos-Garcia, Tarunveer S. Ahluwalia, Signe A. Winther, Peter Henriksen, Mina Ali, Yong Fan, Evelina Stankevic, Liwei Lyu, Josef K. Vogt, Torben Hansen, Cristina Legido-Quigley, Peter Rossing, Oluf Pedersen
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Aims/hypothesisTo identify novel pathophysiological signatures of longstanding type 1 diabetes (T1D) with and without albuminuria we investigated the gut microbiome and blood metabolome in individuals with T1D and healthy controls (HC). We also mappe
Externí odkaz:
https://doaj.org/article/2401ecd0361443519f9f99e32bbb9ad5