Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Cristina Lagido"'
Autor:
Debbie McLaggan, Maria R Amezaga, Eleni Petra, Andrew Frost, Elizabeth I Duff, Stewart M Rhind, Paul A Fowler, L Anne Glover, Cristina Lagido
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46503 (2012)
A transgenic strain of the model nematode Caenorhabditis elegans in which bioluminescence reports on relative, whole-organism ATP levels was used to test an environmentally-relevant mixture of pollutants extracted from processed sewage sludge. Change
Externí odkaz:
https://doaj.org/article/2995af10c76944c08a07d4e25732660d
Publikováno v:
Current Protocols in Toxicology
Mitochondria are a target of many drugs and environmental toxicants; however, how toxicant-induced mitochondrial dysfunction contributes to the progression of human disease remains poorly understood. To address this issue, in vivo assays capable of r
Publikováno v:
Journal of Visualized Experiments.
The multicellular model organism Caenorhabditis elegans is a small nematode of approximately 1 mm in size in adulthood that is genetically and experimentally tractable. It is economical and easy to culture and dispense in liquid medium which makes it
Publikováno v:
FEMS microbiology ecology. 44(1)
Quantitative models of bacterial conjugation are useful tools in environmental risk assessment and in studies of the ecology and evolution of bacterial communities. We constructed a mathematical model for gene transfer between bacteria growing on a s
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 109(1)
Sublethal metabolic effects are informative toxicological end points. We used a rapid quantitative metabolic end point, bioluminescence of firefly luciferase expressing Caenorhabditis elegans, to assess effects of sublethal chronic exposure (19 h) to
Publikováno v:
BMC Physiology
BMC Physiology, Vol 8, Iss 1, p 7 (2008)
BMC Physiology, Vol 8, Iss 1, p 7 (2008)
Background The ATP levels of an organism are an important physiological parameter that is affected by genetic make up, ageing, stress and disease. Results We have generated luminescent C. elegans through ubiquitous, constitutive expression of firefly
Autor:
Maria R. Amezaga, Andrew Frost, Eleni Petra, Paul Fowler, Debbie McLaggan, Cristina Lagido, Stewart M. Rhind, L. Anne Glover, E. I. Duff
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46503 (2012)
PLoS ONE
PLoS ONE
A transgenic strain of the model nematode Caenorhabditis elegans in which bioluminescence reports on relative, whole-organism ATP levels was used to test an environmentally-relevant mixture of pollutants extracted from processed sewage sludge. Change
Publikováno v:
FEBS Letters. (1):36-39
We describe a novel approach to assess toxicity to the free-living nematode Caenorhabditis elegans that relies on the ability of firefly luciferase to report on endogenous ATP levels. We have constructed bioluminescent C. elegans with the luc gene un
Autor:
Lesley Anne Glover, Cristina Lagido, Kenneth Stuart Killham, Andrew J. Porter, Jonathan Pettitt, Graeme I. Paton, R. P. Hollis
Publikováno v:
FEBS Letters. (2):140-142
This study determined that the bacterial luciferase fusion gene (luxAB) was not a suitable in vivo gene reporter in the model eukaryotic organisms Saccharomyces cerevisiae and Caenorhabditis elegans. LuxAB expressing S. cerevisiae strains displayed d
Autor:
Cristina Lagido
Publikováno v:
University of Aberdeen-PURE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64d9d61a2156fa99fa3b9b87153d7665
https://abdn.pure.elsevier.com/en/en/researchoutput/transgenic-caenorhabditis-elegans-as-biosensors(53d3ccf6-ac64-453a-9af0-4d66d7b805a1).html
https://abdn.pure.elsevier.com/en/en/researchoutput/transgenic-caenorhabditis-elegans-as-biosensors(53d3ccf6-ac64-453a-9af0-4d66d7b805a1).html