Zobrazeno 1 - 10
of 208
pro vyhledávání: '"Cristina Kenney"'
Autor:
Shari R Atilano, Daniel H Lee, Paula S Fukuhara, Marilyn Chwa, Anthony B Nesburn, Nitin Udar, Cristina Kenney
Publikováno v:
Journal of Ophthalmic & Vision Research, Vol 14, Iss 1, Pp 62-70 (2019)
Purpose: To compare the levels of gene expression for enzymes involved in production and elimination of reactive oxygen/nitrogen species (ROS/RNS) in normal human corneal cells (NL cells) with those in human corneal cells with keratoconus (KC cells)
Externí odkaz:
https://doaj.org/article/6ad195d8ae534db09f9ff1c9f6e66a31
Autor:
Ashish U Sapkal, Sonali Nashine, Saffar Mansoor, Vishal R Sharma, Claudio A Ramirez, Rafael Z Migon, Navin K Gupta, Marilyn Chwa, Baruch D Kuppermann, Cristina Kenney
Publikováno v:
Journal of Ophthalmic & Vision Research, Vol 13, Iss 4, Pp 419-425 (2018)
Purpose: The aim of this study was to examine the effect of 17β-estradiol on Benzo(e)pyrene [B(e)P]-induced toxicity in ARPE-19 cells. Methods: We pretreated ARPE-19 cells with 20 nM and 40 nM 17β-estradiol for 6 hours, followed by addition of 300
Externí odkaz:
https://doaj.org/article/06a440388809425c9a4d812276df9c44
Autor:
Rodrigo Donato Costa, Farid José Thomaz Neto, M. Tarek Moustafa, Shari R. Atilano, Marilyn Chwa, Javier Cáceres-del-Carpi, Mohamed Hamid Mohamed, M. Cristina Kenney, Baruch D. Kuppermann
Publikováno v:
International Journal of Retina and Vitreous, Vol 9, Iss 1, Pp 1-11 (2023)
Abstract Purpose The present study tests the hypothesis that mitochondrial genes have retrograde signaling capacity that influences the expression of nuclear genes related to angiogenesis pathways. Cytoplasmic hybrid (cybrid) in vitro cell lines with
Externí odkaz:
https://doaj.org/article/45036aa2efb947bea20f5bdab0f2bd3c
Autor:
Andrew H. Dolinko, Marilyn Chwa, Kevin Schneider, Mithalesh K. Singh, Shari Atilano, Jie Wu, M. Cristina Kenney
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Diabetic retinopathy (DR) is the most common diabetic microvascular complication and cause of blindness in adults under the age of 65. Our results suggest that, when comparing transcriptomes of cultures grown in hypoxic conditions versus roo
Externí odkaz:
https://doaj.org/article/685d2d01f82643eb895625f5bfce2512
Autor:
Kayla M. White, Itamar Livnat, Caroline R. Frambach, John Doan, Urmi V. Mehta, Clara Yuh, Anton M. Palma, Kimberly A. Jameson, M. Cristina Kenney, Mitul C. Mehta, Chantal J. Boisvert, Wade R. Crow, Andrew W. Browne
Publikováno v:
International Journal of Retina and Vitreous, Vol 9, Iss 1, Pp 1-11 (2023)
Abstract Background Cone contrast threshold testing (CCT) provides quantitative measurements of color and contrast function to reveal changes in vision quality that are not standard endpoints in clinical trials. We utilize CCT to measure visual funct
Externí odkaz:
https://doaj.org/article/236640ec690d443ebce87df140fb7f09
Autor:
Lata Singh, Shari Atilano, Marilyn Chwa, Mithalesh K. Singh, Mustafa Ozgul, Anthony Nesburn, M. Cristina Kenney
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 11025 (2023)
This study uses personalized chronic lymphoblastic leukemia (CLL) cybrid cells to test various drugs/agents designed to improve mitochondrial function and cell longevity. Age-matched control (NL) and CLL cybrids were created. The NL and CLL cybrids w
Externí odkaz:
https://doaj.org/article/21b25168f28d4aabaf747eba90ca9d19
Autor:
Nasim Salimiaghdam, Lata Singh, Mithalesh Kumar Singh, Marilyn Chwa, Shari Atilano, Zahra Mohtashami, Anthony Nesburn, Baruch D. Kuppermann, M. Cristina Kenney
Publikováno v:
Antioxidants, Vol 12, Iss 7, p 1326 (2023)
The aim of this study is to investigate the therapeutic potential of higher doses of PU-91, quercetin, or in combination on transmitochondrial cybrid cell lines with various mtDNA haplogroups derived from patients with age-related macular degeneratio
Externí odkaz:
https://doaj.org/article/2a0bd16b238b4a2282d42c2f31c00c2a
Autor:
Mustafa Ozgul, Anthony B. Nesburn, Nader Nasralla, Benjamin Katz, Enes Taylan, Baruch D. Kuppermann, Maria Cristina Kenney
Publikováno v:
Biomolecules, Vol 13, Iss 3, p 515 (2023)
Humanin is the first identified mitochondrial-derived peptide. Humanin-G (HNG) is a variant of Humanin that has significantly higher cytoprotective properties. Here, we describe the stability features of HNG in different conditions and characterize H
Externí odkaz:
https://doaj.org/article/6892b61e27534bb2a6d0a9c4698b84b3
Autor:
Hossein Hasanpour, Maria Cristina Kenney, Baruch D. Kuppermann, Mohammad Riazi Esfahani, Mozhgan Rezaei Kanavi, Mithalesh Kumar Singh, Masoud Soheilian
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 4, p 1259 (2023)
The purpose of this study is to evaluate the concentration of vascular endothelial growth factor (VEGF) in the vitreous humor of patients with primary rhegmatogenous retinal detachment (RRD). This is a prospective case control study. Eighteen patient
Externí odkaz:
https://doaj.org/article/e7d5e391430b401e84c54afcb084fca7
Autor:
Zahra Mohtashami, Mithalesh Kumar Singh, Farid Thomaz Neto, Nasim Salimiaghdam, Hossein Hasanpour, M. Cristina Kenney
Publikováno v:
Antioxidants, Vol 12, Iss 2, p 518 (2023)
Mitochondrial open reading frame of the 12S rRNA type-c (MOTS-c) is the most unearthed peptide encoded by mitochondrial DNA (mtDNA). It is an important regulator of the nuclear genome during times of stress because it promotes an adaptive stress resp
Externí odkaz:
https://doaj.org/article/c4b4ac9fb261441bbd4b8979fe494946