Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Cristina Jimenez-Luna"'
Autor:
Francisco Quiñonero, Cristina Mesas, Kevin Doello, Laura Cabeza, Gloria Perazzoli, Cristina Jimenez-Luna, Ana Rosa Rama, Consolación Melguizo, Jose Prados
Publikováno v:
Cancer Biology & Medicine, Vol 16, Iss 4, Pp 688-699 (2019)
Pancreatic ductal adenocarcinoma (PDAC) has one of the highest mortality rates among all cancer types. Its delayed diagnosis precludes curative resection, thus most of the current therapies against PDAC are based on chemo- and radiotherapy. Unfortuna
Externí odkaz:
https://doaj.org/article/8709a13fe2364c74bf389f3b5ae6e841
Autor:
Jaime A. Oliver, Jaime Gómez-Millán, Jose A. Medina, Laura Cabeza, Gloria Perazzoli, Cristina Jimenez-Luna, Kevin Doello, Raúl Ortiz
Publikováno v:
Balkan Medical Journal, Vol 36, Iss 5, Pp 283-286 (2019)
Aims: To analyze the clinical relevance of O6-methylguanine-DNA methyltransferase in rectal adenocarcinoma treated with chemoradiotherapy followed by surgery. Methods: Tissue samples from 29 rectal adenocarcinoma patients were obtained after chemora
Externí odkaz:
https://doaj.org/article/18a282223f4c45379944876be55e2d1f
Autor:
Cristina Jimenez-Luna, Ariadna Martin-Blazquez, Carmelo Dieguez-Castillo, Caridad Diaz, Jose Luis Martin-Ruiz, Olga Genilloud, Francisca Vicente, Jose Perez del Palacio, Jose Prados, Octavio Caba
Publikováno v:
Metabolites, Vol 10, Iss 11, p 423 (2020)
Pancreatogenic diabetes mellitus (T3cDM) is a highly frequent complication of pancreatic disease, especially chronic pancreatitis, and it is often misdiagnosed as type 2 diabetes mellitus (T2DM). A correct diagnosis allows the appropriate treatment o
Externí odkaz:
https://doaj.org/article/46c52357905e44a7ba031193412cd2b3
Autor:
Antonio Irigoyen, Cristina Jimenez-Luna, Manuel Benavides, Octavio Caba, Javier Gallego, Francisco Manuel Ortuño, Carmen Guillen-Ponce, Ignacio Rojas, Enrique Aranda, Carolina Torres, Jose Prados
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0194844 (2018)
Applying differentially expressed genes (DEGs) to identify feasible biomarkers in diseases can be a hard task when working with heterogeneous datasets. Expression data are strongly influenced by technology, sample preparation processes, and/or labeli
Externí odkaz:
https://doaj.org/article/baeb6d91941644d08560eebbf9456261
Autor:
Jesus Corria-Osorio, Santiago J. Carmona, Evangelos Stefanidis, Massimo Andreatta, Yaquelin Ortiz-Miranda, Tania Muller, Ioanna A. Rota, Isaac Crespo, Bili Seijo, Wilson Castro, Cristina Jimenez-Luna, Leonardo Scarpellino, Catherine Ronet, Aodrenn Spill, Evripidis Lanitis, Pedro Romero, Sanjiv A. Luther, Melita Irving, George Coukos
Publikováno v:
Nature Immunology. 24:869-883
To date, no immunotherapy approaches have managed to fully overcome T-cell exhaustion, which remains a mandatory fate for chronically activated effector cells and a major therapeutic challenge. Understanding how to reprogram CD8+ tumor-infiltrating l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04c4d22cef27ec5aaa15c3dd76795b3f
https://doi.org/10.1038/s41590-023-01477-2
https://doi.org/10.1038/s41590-023-01477-2
Autor:
Ana Isabel Tristán, Cristina Jiménez-Luna, Ana Cristina Abreu, Francisco Manuel Arrabal-Campos, Ana del Mar Salmerón, Firma Isabel Rodríguez, Manuel Ángel Rodríguez Maresca, Antonio Bernardino García, Consolación Melguizo, Jose Prados, Ignacio Fernández
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The COVID-19 pandemic remains a significant global health threat, with uncertainties persisting regarding the factors determining whether individuals experience mild symptoms, severe conditions, or succumb to the disease. This study presents
Externí odkaz:
https://doaj.org/article/04bb61772fd54dceaf439c07582ecfe5
Autor:
Francisco Carrillo-Perez, Octavio Caba, Cristina Jimenez-Luna, Francisco Ortuño, Daniel Castillo-Secilla, Luis Javier Herrera, Jose Prados, Ignacio Rojas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff75728b4e090b50c1eb1b343ac1bef9
https://doi.org/10.2139/ssrn.4409594
https://doi.org/10.2139/ssrn.4409594
Autor:
Jesus Corria-Osorio, Santiago J. Carmona, Evangelos Stefanidis, Massimo Andreatta, Tania Muller, Yaquelin Ortiz-Miranda, Bili Seijo, Wilson Castro, Cristina Jimenez-Luna, Leonardo Scarpellino, Catherine Ronet, Aodrenn Spill, Evripidis Lanitis, Sanjiv A. Luther, Pedro Romero, Melita Irving, George Coukos
SummaryAdoptive immunotherapy offers opportunities to reprogram T cells and the tumor microenvironment. Orthogonal engineering of adoptively transferred T cells with an IL-2Rβγ-binding IL-2 variant, PD1-decoy and IL-33 led to cell-autonomous T-cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::895c1948dbf29445736e00a45b7df444
https://doi.org/10.1101/2022.02.18.481059
https://doi.org/10.1101/2022.02.18.481059
Autor:
Jaime A, Oliver, Raul, Ortiz, Cristina, Jimenez-Luna, Laura, Cabeza, Gloria, Perazzoli, Octavio, Caba, Cristina, Mesas, Consolacion, Melguizo, Jose, Prados
Publikováno v:
Journal of biosciences. 45
Cancer stem cells (CSCs) from colorectal cancer (CRC), characterized by CD133 expression, have been associated with 5-fluorouracile (5-FU) chemoresistance. DNA repair mechanisms, such as O6-alkylguanine DNA alkyltransferase (MGMT) and mismatch repair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c8e26f248e865c0a6c18af0d82870b82
https://pubmed.ncbi.nlm.nih.gov/33097678
https://pubmed.ncbi.nlm.nih.gov/33097678
Autor:
Francisco Quiñonero, Cristina Mesas, Jose A. Muñoz-Gámez, Cristina Jiménez-Luna, Gloria Perazzoli, Jose Prados, Consolación Melguizo, Raul Ortiz
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 155, Iss , Pp 113669- (2022)
Pancreatic cancer (PC) is one of the tumors with the lowest survival rates due to the poor efficacy of the treatments currently used. Gemcitabine (GMZ), one of the chemotherapeutic agents employed when the tumor is unresectable, frequently fails due
Externí odkaz:
https://doaj.org/article/7b9b8406383f446f9ff8820d9b5b64e3