Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Cristina I Linde"'
Autor:
John M Hamlyn, Cristina I Linde, Junjie Gao, Bing S Huang, Vera A Golovina, Mordecai P Blaustein, Frans H H Leenen
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108916 (2014)
Central nervous system (CNS) administration of angiotensin II (Ang II) raises blood pressure (BP). The rise in BP reflects increased sympathetic outflow and a slower neuromodulatory pressor mechanism mediated by CNS mineralocorticoid receptors (MR).
Externí odkaz:
https://doaj.org/article/0df3a099a042406bab64d41201224757
Autor:
Marco Kessler, Robert Solinga, Boris Tchernychev, Inmaculada Silos-Santiago, Nadia A. Ameen, David Arthur, Md. Kaimul Ahsan, Gerhard Hannig, Cristina I. Linde
Publikováno v:
Physiological Reports
The transmembrane receptor guanylyl cyclase‐C (GC‐C), expressed on enterocytes along the intestine, is the molecular target of the GC‐C agonist peptide linaclotide, an FDA‐approved drug for treatment of adult patients with Irritable Bowel Syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33660aac1a5e50be1c19e49cfedb2c27
https://pubmed.ncbi.nlm.nih.gov/28592587
https://pubmed.ncbi.nlm.nih.gov/28592587
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 303:H784-H794
The mechanisms by which NaCl raises blood pressure (BP) in hypertension are unresolved, but much evidence indicates that endogenous ouabain is involved. In rodents, arterial smooth muscle cell (ASMC) Na+pumps with an α2-catalytic subunit (ouabain EC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01fb706f6137e8650ee6df5b29382c40
https://doi.org/10.1152/ajpheart.00399.2012
https://doi.org/10.1152/ajpheart.00399.2012
Publikováno v:
American journal of physiology. Cell physiology. 304(11)
Recent findings indicate that histidine triad nucleotide-binding protein 1 (HINT1) is implicated in the pathophysiology of certain psychiatric disorders and also exhibits tumor suppressor properties. However, the authentic functions of HINT1 in cellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5de1cc0edc05f2b261577ece201bb235
https://pubmed.ncbi.nlm.nih.gov/23576580
https://pubmed.ncbi.nlm.nih.gov/23576580
Autor:
Maria V. Pulina, John M. Hamlyn, Sergey G. Baryshnikov, Cristina I. Linde, Alessandra Zulian, Italia Papparella, Vera A. Golovina
Publikováno v:
American journal of physiology. Cell physiology. 304(4)
Cardiotonic steroids (CTS) of the strophanthus and digitalis families have opposing effects on long-term blood pressure (BP). This implies hitherto unrecognized divergent signaling pathways for these CTS. Prolonged ouabain treatment upregulates Ca2+e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3d5b44f7d85ab0e0367e58e2e86a02
https://pubmed.ncbi.nlm.nih.gov/23195071
https://pubmed.ncbi.nlm.nih.gov/23195071
Autor:
Mordecai P. Blaustein, Maria V. Pulina, Patrizia Ferrari, Cristina I. Linde, Vera A. Golovina, Alessandra Zulian, John M. Hamlyn, Eiji Karashima, Sergey G. Baryshnikov
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461447559
Arterial smooth muscle (ASM) Na(+)/Ca(2+) exchanger type 1 (NCX1) and TRPC/Orai-containing receptor/store-operated cation channels (ROC/SOC) are clustered with α2 Na(+) pumps in plasma membrane microdomains adjacent to the underlying junctional sarc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4410cf825965f5ae13109e914b6271f
https://doi.org/10.1007/978-1-4614-4756-6_31
https://doi.org/10.1007/978-1-4614-4756-6_31
Autor:
John M Hamlyn, Frans H Leenen, Vera A Golovina, Cristina I Linde, Junjie Gao, Bing Huang, Monir Ahmad, Ling Chen, Meng Li, Mordecai P Blaustein
Publikováno v:
Hypertension. 60
The brain, together with altered arterial function, plays a crucial role in the pathogenesis of hypertension. We have suggested that endogenous ouabain (EO), and its actions on arterial Na + and Ca 2+ transporters, are key in some forms of hypertensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b4647f0fff8f6c9586744edcb122151
https://doi.org/10.1161/hyp.60.suppl_1.a419
https://doi.org/10.1161/hyp.60.suppl_1.a419
Autor:
Patrizia Ferrari, John M. Hamlyn, Withrow Gil Wier, Alessandra Zulian, Vera A. Golovina, Mordecai P. Blaustein, Hema Raina, Eiji Karashima, Cristina I. Linde
The Milan hypertensive strain (MHS) rats are a genetic model of hypertension with adducin gene polymorphisms linked to enhanced renal tubular Na+ reabsorption. Recently we demonstrated that Ca2+ signaling is augmented in freshly isolated mesenteric a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d20bddba3255f4f20656b1de97a1f38
http://hdl.handle.net/11577/3225554
http://hdl.handle.net/11577/3225554
Publikováno v:
American journal of physiology. Cell physiology. 300(6)
The relationship between altered metabolism of the amyloid-β precursor protein (APP) and Alzheimer's disease is well established but the physiological roles of APP still remain unclear. Here, we studied Ca2+ signaling in primary cultured and freshly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a285c3bfbbf2e7358eefa57fd1e949cb
https://pubmed.ncbi.nlm.nih.gov/21368296
https://pubmed.ncbi.nlm.nih.gov/21368296
Autor:
Alessandra Zulian, Sergey G. Baryshnikov, John M. Hamlyn, Patrizia Ferrari, Cristina I. Linde, Vera A. Golovina
The Milan hypertensive strain (MHS) of rats is a model for hypertension in humans. Inherited defects in renal function have been well studied in MHS rats, but the mechanisms that underlie the elevated vascular resistance are unclear. Altered Ca2+sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4be40d97793e1eb9810e04257cd51a00
https://europepmc.org/articles/PMC2944478/
https://europepmc.org/articles/PMC2944478/