Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Cristina Guardia‐Laguarta"'
Autor:
Hila Avisar, Cristina Guardia-Laguarta, Matthew Surface, Nikos Papagiannakis, Matina Maniati, Roubina Antonellou, Dimitra Papadimitriou, Christos Koros, Aglaia Athanassiadou, Serge Przedborski, Boaz Lerner, Leonidas Stefanis, Estela Area-Gomez, Roy N. Alcalay
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract Lipid profiles in biological fluids from patients with Parkinson’s disease (PD) are increasingly investigated in search of biomarkers. However, the lipid profiles in genetic PD remain to be determined, a gap of knowledge of particular inte
Externí odkaz:
https://doaj.org/article/83b6cfbe26d145959efe4f680aa04238
Autor:
Yuhui Liu, Cristina Guardia-Laguarta, Jiang Yin, Hediye Erdjument-Bromage, Brittany Martin, Michael James, Xuejun Jiang, Serge Przedborski
Publikováno v:
Cell Reports, Vol 20, Iss 1, Pp 30-39 (2017)
Along with Parkin, PINK1 plays a critical role in maintaining mitochondrial quality control. Although PINK1 is expressed constitutively, its level is kept low in healthy mitochondria by polyubiquitination and ensuing proteasomal degradation of its ma
Externí odkaz:
https://doaj.org/article/c11d93ee72934d9882e3285305abd642
Autor:
Francesc X. Guix, Tina Wahle, Kristel Vennekens, An Snellinx, Lucía Chávez‐Gutiérrez, Gerard Ill‐Raga, Eva Ramos‐Fernandez, Cristina Guardia‐Laguarta, Alberto Lleó, Muriel Arimon, Oksana Berezovska, Francisco J. Muñoz, Carlos G. Dotti, Bart De Strooper
Publikováno v:
EMBO Molecular Medicine, Vol 4, Iss 7, Pp 660-673 (2012)
Abstract Inherited familial Alzheimer's disease (AD) is characterized by small increases in the ratio of Aβ42 versus Aβ40 peptide which is thought to drive the amyloid plaque formation in the brain of these patients. Little is known however whether
Externí odkaz:
https://doaj.org/article/985e2e3c05864522b29149bd4e6c1b71
Autor:
Nahuai Badiola, Rita Machado de Oliveira, Federico Herrera, Cristina Guardia-Laguarta, Susana A Gonçalves, Marta Pera, Marc Suárez-Calvet, Jordi Clarimon, Tiago Fleming Outeiro, Alberto Lleó
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26609 (2011)
BackgroundThe simultaneous accumulation of different misfolded proteins in the central nervous system is a common feature in many neurodegenerative diseases. In most cases, co-occurrence of abnormal deposited proteins is observed in different brain r
Externí odkaz:
https://doaj.org/article/b383f4ea139f4787b85f88b1e9deb2c4
Publikováno v:
Current Opinion in Clinical Nutrition and Metabolic Care. 23:68-75
Purpose of review The purpose of this brief review is to gain an understanding on the multiple roles that lipids exert on the brain, and to highlight new ideas in the impact of lipid homeostasis in the regulation of synaptic transmission. Recent find
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc92a7d26fc755eb6e00b2c1fd6edcaa
https://doi.org/10.1097/mco.0000000000000634
https://doi.org/10.1097/mco.0000000000000634
Publikováno v:
Alzheimer's & Dementia. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23388cb1a4d41d3d8eba2bb443f3a9a8
https://doi.org/10.1002/alz.038479
https://doi.org/10.1002/alz.038479
Autor:
Rishi R. Agrawal, Irina G Stavrovskaya, So Yeon Koo, Yimeng Xu, Cristina Guardia-Laguarta, Kevin R Velasco, Delfina Larrea, Andrew Sproul, Amanda M. Snead, Marta Pera, Jorge Montesinos, Taekyung D Yun, Estela Area-Gomez
Publikováno v:
The EMBO Journal
The link between cholesterol homeostasis and cleavage of the amyloid precursor protein (APP), and how this relationship relates to Alzheimer's disease (AD) pathogenesis, is still unknown. Cellular cholesterol levels are regulated through crosstalk be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d8aba0710fc8c77312d55f67e85fb34
http://europepmc.org/articles/PMC7560219
http://europepmc.org/articles/PMC7560219
Publikováno v:
Current opinion in clinical nutrition and metabolic care. 23(2)
The purpose of this brief review is to gain an understanding on the multiple roles that lipids exert on the brain, and to highlight new ideas in the impact of lipid homeostasis in the regulation of synaptic transmission.Recent data underline the cruc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b65cbeeccb3b854dffae361fd4ec8c34
https://pubmed.ncbi.nlm.nih.gov/32004239
https://pubmed.ncbi.nlm.nih.gov/32004239
Autor:
Jiang Yin, Cristina Guardia-Laguarta, Serge Przedborski, Brittany Martin, Michael N.G. James, Yuhui Liu, Hediye Erdjument-Bromage, Xuejun Jiang
Publikováno v:
Cell Reports, Vol 20, Iss 1, Pp 30-39 (2017)
Cell reports
Cell reports
SUMMARY Along with Parkin, PINK1 plays a critical role in maintaining mitochondrial quality control. Although PINK1 is expressed constitutively, its level is kept low in healthy mitochondria by polyubiquitination and ensuing proteasomal degradation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8294b45686b98c587ab416cf2fcddf9c
https://doi.org/10.1016/j.celrep.2017.06.022
https://doi.org/10.1016/j.celrep.2017.06.022
Autor:
Sy Koo, Cristina Guardia-Laguarta, Delfina Larrea, Yimeng Xu, Andrew Sproul, Marta Pera, Estela Area-Gomez, Amanda M. Snead, Jorge Montesinos, Kevin R Velasco, Rishi R. Agrawal
The link between cholesterol homeostasis and the cleavage of the amyloid precursor protein (APP), and their relationship to the pathogenesis of Alzheimer’s disease (AD) is still unknown. Cellular cholesterol levels are regulated by a crosstalk betw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16c4de1b41fb4d15b7fded0ca928f2c8
