Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Cristina Grosanu"'
Autor:
Balu D. Dherange, Mingbin Yuan, Christopher B. Kelly, Christopher A. Reiher, Cristina Grosanu, Kathleen J. Berger, Osvaldo Gutierrez, Mark D. Levin
Publikováno v:
Journal of the American Chemical Society.
Selective functional group interconversions in complex molecular settings underpin many of the challenges facing modern organic synthesis. Currently, a privileged subset of functional groups dominates this landscape, while others, despite their abund
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::287dcb6ea27eaa3c0ccc7dffca72e5b6
https://pubmed.ncbi.nlm.nih.gov/36548788
https://pubmed.ncbi.nlm.nih.gov/36548788
Autor:
Albert J. Robichaud, Cristina Grosanu, Jean Y. Zhang, Lo Jennifer Rebecca, Lee E. Schechter, Thomas A. Comery, Kevin G. Liu, Li Di, Guo Ming Zhang, Yanxuan Cai, Alexander Greenfield, Edward H. Kerns, Deborah L. Smith, James F. Mattes, Dianne Kowal
Publikováno v:
Bioorganic & Medicinal Chemistry. 19:650-662
As part of our efforts to develop agents for cognitive enhancement, we have been focused on the 5-HT(6) receptor in order to identify potent and selective ligands for this purpose. Herein we report the identification of a novel series of 3-sulfonylin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::248eca77cccc3b29d8ab7aea26b0e58e
https://doi.org/10.1016/j.bmc.2010.10.033
https://doi.org/10.1016/j.bmc.2010.10.033
Autor:
Cristina Grosanu, Alexander Greenfield
Publikováno v:
Tetrahedron Letters. 49:6300-6303
An efficient protocol for a one-pot synthesis of mono-sulfonamides has been developed. It features utilization of excess of sulfonylating agent followed by base mediated recovery of the primary sulfonamide.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a81e53fcce53bf0db29ae17b2ed16ce
https://doi.org/10.1016/j.tetlet.2008.08.054
https://doi.org/10.1016/j.tetlet.2008.08.054
Autor:
Alexander Greenfield, Tikva Carrick, John A. Butera, Dianne Kowal, John Dunlop, Brian Jow, Cristina Grosanu, Qiang Lu, Beal McIlvain, John P. Williams
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:4985-4988
Excitatory amino acid transporters (EAATs) play a pivotal role in maintaining glutamate homeostasis in the mammalian central nervous system, with the EAAT-2 subtype thought to be responsible for the bulk of the glutamate uptake in forebrain regions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c5a1dd7bbb3e90347e18220f7cf664f
https://doi.org/10.1016/j.bmcl.2005.08.003
https://doi.org/10.1016/j.bmcl.2005.08.003
Autor:
Jean Zhang, Julie A. Brennan, Chris G. Kruse, Jan-Hendrik Reinders, Dianne Kowal, Geraldine Ruth Mcfarlane, Feenstra Roelof W, Sara Núñez-García, Andrew C. McCreary, Karen L. Marquis, Radka Graf, Mark H. Pausch, Alexander Greenfield, Margaret Lai, Albert J. Robichaud, Farhana Pruthi, Tikva Carrick, David P. Rotella, Cristina Grosanu, Steven M. Grauer, Rajiah A. Denny, Kelly Sullivan, Rachel Navarra, Martina A.W. van der Neut
Publikováno v:
Bioorganicmedicinal chemistry letters. 19(19)
A 5-fluoro-tetrahydrocarbazole serotonin reuptake inhibitor (SRI) building block was combined with a variety of linkers and dopamine D2 receptor ligands in an attempt to identify potent D2 partial agonist/SRI molecules for treatment of schizophrenia.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d888ee9ef744cb0b6c28720c1c17096
https://pubmed.ncbi.nlm.nih.gov/19720528
https://pubmed.ncbi.nlm.nih.gov/19720528
Autor:
Alexander Greenfield, Cristina Grosanu
Publikováno v:
ChemInform. 40
An efficient protocol for a one-pot synthesis of mono-sulfonamides has been developed. It features utilization of excess of sulfonylating agent followed by base mediated recovery of the primary sulfonamide.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab224f1d89fc1c3f8bee080f0777ab23
https://doi.org/10.1002/chin.200907067
https://doi.org/10.1002/chin.200907067
Autor:
Alexander Greenfield, John Dunlop, Brian Jow, Cristina Grosanu, Beal McIlvain, Tikva Carrick, John A. Butera, John G. Williams, Qiang Lu, Dianne Kowal
Publikováno v:
ChemInform. 37
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c0b069dcc8268069421866d391c862f
https://doi.org/10.1002/chin.200608166
https://doi.org/10.1002/chin.200608166
Autor:
Dianne Kowal, Cristina Grosanu, Stephen Lin, Robert E. Petroski, Brian Jow, John Dunlop, John A. Butera, Tikva Carrick, Alexander Greenfield, Alan C. Foster, John A. Williams, Beal McIlvain, Kristi Fan, Qiang Lu
Publikováno v:
Molecular pharmacology. 68(4)
In this study, we describe the pharmacological characterization of novel aryl-ether, biaryl, and fluorene aspartic acid and diaminopropionic acid analogs as potent inhibitors of EAAT2, the predominant glutamate transporter in forebrain regions. The r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::620dcbabe015ca0a8a07c8907e673c38
https://pubmed.ncbi.nlm.nih.gov/16014807
https://pubmed.ncbi.nlm.nih.gov/16014807