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of 7
pro vyhledávání: '"Cristina Gardini"'
Autor:
Cristina Gardini, Elena Urso, Marco Guerrini, René van Herpen, Pauline de Wit, Annamaria Naggi
Publikováno v:
Molecules, Vol 22, Iss 7, p 1116 (2017)
Danaparoid sodium salt, is the active component of ORGARAN, an anticoagulant and antithrombotic drug constituted of three glycosaminoglycans (GAGs) obtained from porcine intestinal mucosa extracts. Heparan sulfate is the major component, dermatan sul
Externí odkaz:
https://doaj.org/article/c2b979568ffd488ebe46e06dab70d883
Autor:
Cristina Gardini, Giovanni Boccardi, Marco Guerrini, Edwin Kellenbach, Maarten Lunenburg, Jan-Ytzen van der Meer, Annamaria Naggi, Elena Urso
Publikováno v:
Thrombosis and Haemostasis.
Objective Danaparoid sodium is a biopolymeric complex drug composed of the most abundant heparan sulfate (HS) followed in descending order by dermatan sulfate (DS) and chondroitin sulfate (CS). This composite nature explains its peculiar antithrombot
Autor:
Giulia Mazzini, Antonella Bisio, Marco Guerrini, Cristina Gardini, Anna Alekseeva, Annamaria Naggi
Publikováno v:
Carbohydrate polymers. 273
Enoxaparin, widely used antithrombotic drug, is a polydisperse glycosaminoglycan with highly microheterogeneous structure dictated by both parent heparin heterogeneity and depolymerization conditions. While the process-related modifications of intern
Autor:
Benito Casu, Elena Urso, Giangiacomo Torri, Anna Alekseeva, Lucio Mauri, Giuseppe Cassinelli, Giacomo Pedrinola, Marcello Iacomini, Annamaria Naggi, Marco Guerrini, Cristina Gardini, Valentina Baigorria
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 118
The major compositional differences between bovine mucosal heparin (BMH) and the currently employed porcine mucosal heparin (PMH) have been reported to essentially consist of reduced 6-O-sulfation of the glucosamine residues in BMH and somewhat lower
Autor:
Annamaria Naggi, Marco Guerrini, Cristina Gardini, Elena Urso, Pauline de Wit, René van Herpen
Publikováno v:
Molecules; Volume 22; Issue 7; Pages: 1116
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules, Vol 22, Iss 7, p 1116 (2017)
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules, Vol 22, Iss 7, p 1116 (2017)
Danaparoid sodium salt, is the active component of ORGARAN, an anticoagulant and antithrombotic drug constituted of three glycosaminoglycans (GAGs) obtained from porcine intestinal mucosa extracts. Heparan sulfate is the major component, dermatan sul
Autor:
Cristina Gardini, Laura Muzi, Marco Guerrini, Eleonora Macchi, Giangiacomo Torri, Edwin A. Yates, Timothy R. Rudd
Publikováno v:
Analytical chemistry. 84(15)
Risks of contamination of the major clinical anticoagulant heparin can arise from deliberate adulteration with unnatural or natural polysaccharides, including heparin from other animal sources, other natural products, or artifacts of manufacture, and
Autor:
Derek J. Langeslay, Cristina Gardini, Annamaria Naggi, Cynthia K. Larive, Elena Urso, Giangiacomo Torri
Publikováno v:
Journal of chromatography. A. 1292
Heparin is a complex mixture of sulfated linear carbohydrate polymers. It is widely used as an antithrombotic drug, though it has been shown to have a myriad of additional biological activities. Heparin is often partially depolymerized in order to de