Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Cristina Florindo"'
Autor:
Hana Pavlu-Pereira, Maria João Silva, Cristina Florindo, Sílvia Sequeira, Ana Cristina Ferreira, Sofia Duarte, Ana Luísa Rodrigues, Patrícia Janeiro, Anabela Oliveira, Daniel Gomes, Anabela Bandeira, Esmeralda Martins, Roseli Gomes, Sérgia Soares, Isabel Tavares de Almeida, João B. Vicente, Isabel Rivera
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-14 (2020)
Abstract Background The pyruvate dehydrogenase complex (PDC) catalyzes the irreversible decarboxylation of pyruvate into acetyl-CoA. PDC deficiency can be caused by alterations in any of the genes encoding its several subunits. The resulting phenotyp
Externí odkaz:
https://doaj.org/article/37f927c3888f4a17b355b563b8381907
Autor:
Patrícia Lipari Pinto, Cristina Florindo, Patrícia Janeiro, Rita Loureiro Santos, Sandra Mexia, Hugo Rocha, Isabel Tavares de Almeida, Laura Vilarinho, Ana Gaspar
Publikováno v:
Nutrients, Vol 14, Iss 20, p 4397 (2022)
The early diagnosis of and intervention in vitamin B12 deficiency in exclusively breastfed infants by mothers with low vitamin B12 is crucial in preventing possible irreversible neurologic damage, megaloblastic anemia, and failure to thrive. We asses
Externí odkaz:
https://doaj.org/article/3ed7375c715b4ff49968ec6d1812da93
Autor:
Inês V. da Silva, Sean Gullette, Cristina Florindo, Neil K. Huang, Thomas Neuberger, A. Catharine Ross, Graça Soveral, Rita Castro
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 1159 (2022)
Ketogenic diets (KDs) are very low-carbohydrate, very high-fat diets which promote nutritional ketosis and impact energetic metabolism. Aquaporins (AQPs) are transmembrane channels that facilitate water and glycerol transport across cell membranes an
Externí odkaz:
https://doaj.org/article/ff6351bd68374b809542341e20a659d9
Autor:
Rita Castro, Courtney A. Whalen, Sean Gullette, Floyd J. Mattie, Cristina Florindo, Sandra G. Heil, Neil K. Huang, Thomas Neuberger, A. Catharine Ross
Publikováno v:
Nutrients, Vol 13, Iss 10, p 3576 (2021)
Hyperhomocysteneinemia (HHcy) is common in the general population and is a risk factor for atherosclerosis by mechanisms that are still elusive. A hypomethylated status of epigenetically relevant targets may contribute to the vascular toxicity associ
Externí odkaz:
https://doaj.org/article/cb1bc908862a48ba881bc6c40e966c3c
Autor:
Ana Pinheiro, Maria João Silva, Hana Pavlu-Pereira, Cristina Florindo, Madalena Barroso, Bárbara Marques, Hildeberto Correia, Anabela Oliveira, Ana Gaspar, Isabel Tavares de Almeida, Isabel Rivera
Publikováno v:
Data in Brief, Vol 9, Iss C, Pp 68-77 (2016)
This article presents a dataset proving the simultaneous presence of a 5′UTR-truncated PDHA1 mRNA and a full-length PDHA2 mRNA in the somatic cells of a PDC-deficient female patient and all members of her immediate family (parents and brother). We
Externí odkaz:
https://doaj.org/article/fee7be74b25a414788e9722bafdb60e8
Autor:
Inês V. da Silva, Courtney A. Whalen, Floyd J. Mattie, Cristina Florindo, Neil K. Huang, Sandra G. Heil, Thomas Neuberger, A. Catharine Ross, Graça Soveral, Rita Castro
Publikováno v:
Biomedicines, Vol 9, Iss 2, p 150 (2021)
The dysfunction of vascular endothelial cells is profoundly implicated in the pathogenesis of atherosclerosis and cardiovascular disease, the global leading cause of death. Aquaporins (AQPs) are membrane channels that facilitate water and glycerol tr
Externí odkaz:
https://doaj.org/article/e113d91df0f949ccbfe2818017f295ec
Autor:
Courtney A. Whalen, Floyd J. Mattie, Cristina Florindo, Bertrand van Zelst, Neil K. Huang, Isabel Tavares de Almeida, Sandra G. Heil, Thomas Neuberger, A. Catharine Ross, Rita Castro
Publikováno v:
Nutrients, Vol 12, Iss 8, p 2182 (2020)
Hyperhomocysteinemia (HHcy) is a risk factor for atherosclerosis through mechanisms which are still incompletely defined. One possible mechanism involves the hypomethylation of the nuclear histone proteins to favor the progression of atherosclerosis.
Externí odkaz:
https://doaj.org/article/fcbb753367c445cba672e60599aca5d8
Autor:
Helena Caldeira-Araújo, Ruben Ramos, Cristina Florindo, Isabel Rivera, Rita Castro, Isabel Tavares de Almeida
Publikováno v:
Nutrients, Vol 11, Iss 3, p 646 (2019)
Background: Imbalance of homocysteine (Hcy) metabolism links with several pathologies; nevertheless, it is poorly characterized in pediatric populations. This study investigated the impact of age on plasma concentrations of Hcy and relevant biomarker
Externí odkaz:
https://doaj.org/article/c0f022930cd54590ae5055a879188b6c
Autor:
Ruben Esse, Monica S Rocha, Madalena Barroso, Cristina Florindo, Tom Teerlink, Robert M Kok, Yvo M Smulders, Isabel Rivera, Paula Leandro, Pieter Koolwijk, Rita Castro, Henk J Blom, Isabel Tavares de Almeida
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55483 (2013)
Methyltransferases use S-adenosylmethionine (AdoMet) as methyl group donor, forming S-adenosylhomocysteine (AdoHcy) and methylated substrates, including DNA and proteins. AdoHcy inhibits most methyltransferases. Accumulation of intracellular AdoHcy s
Externí odkaz:
https://doaj.org/article/841a09fd4f574ec8993de1f3fe8d9e03
Autor:
Ruben Esse, Monica S. Rocha, Madalena Barroso, Cristina Florindo, Tom Teerlink, Robert M. Kok, Yvo M. Smulders, Isabel Rivera, Paula Leandro, Pieter Koolwijk, Rita Castro, Henk J. Blom, Isabel Tavares de Almeida
Publikováno v:
PLoS ONE, Vol 8, Iss 10 (2013)
Externí odkaz:
https://doaj.org/article/2926133dcba94c76aa6b440ca99c5df0