Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Cristina Faralla"'
Autor:
Cristina Faralla, Effie E Bastounis, Fabian E Ortega, Samuel H Light, Gabrielle Rizzuto, Lei Gao, Denise K Marciano, Salvatore Nocadello, Wayne F Anderson, Jennifer R Robbins, Julie A Theriot, Anna I Bakardjiev
Publikováno v:
PLoS Pathogens, Vol 14, Iss 5, p e1007094 (2018)
During pregnancy, the placenta protects the fetus against the maternal immune response, as well as bacterial and viral pathogens. Bacterial pathogens that have evolved specific mechanisms of breaching this barrier, such as Listeria monocytogenes, pre
Externí odkaz:
https://doaj.org/article/145df8a400814774821df311810559de
Autor:
Cristina Faralla, Matteo M. Metruccio, Matteo De Chiara, Rong Mu, Kathryn A. Patras, Alessandro Muzzi, Guido Grandi, Immaculada Margarit, Kelly S. Doran, Robert Janulczyk
Publikováno v:
mBio, Vol 5, Iss 3 (2014)
ABSTRACT Group B Streptococcus (GBS), in the transition from commensal organisms to pathogens, will encounter diverse host environments and, thus, require coordinated control of the transcriptional responses to these changes. This work was aimed at b
Externí odkaz:
https://doaj.org/article/a8682af27e5a4646af6d0c0c7fdbb1cb
Targeted Amino Acid Substitutions Impair Streptolysin O Toxicity and Group A Streptococcus Virulence
Autor:
Emiliano Chiarot, Cristina Faralla, Nico Chiappini, Giovanna Tuscano, Fabiana Falugi, Gabriella Gambellini, Annarita Taddei, Sabrina Capo, Elena Cartocci, Daniele Veggi, Alessia Corrado, Simona Mangiavacchi, Simona Tavarini, Maria Scarselli, Robert Janulczyk, Guido Grandi, Immaculada Margarit, Giuliano Bensi
Publikováno v:
mBio, Vol 4, Iss 1 (2013)
ABSTRACT Streptolysin O is a potent pore-forming toxin produced by group A Streptococcus. The aims of the present study were to dissect the relative contributions of different structural domains of the protein to hemolytic activity, to obtain a detox
Externí odkaz:
https://doaj.org/article/bb3003ecff814c90b395fe26d22ddb65
Autor:
Lindsay DeVorkin, Juntao (Matt) Mai, Kate Caldwell, Tim Jacobs, Raffi Tonikian, Karine Herve, Yuri Hwang, Cristina Faralla, Wei Wei, Emma Lathouwers, Rhys Chappell, Stefan Hannie, Katherine Lam, Harveer Dhupar, Tran Tran, Melissa Cid, Lena Bolten, Tova Pinsky, Ping Xiang, Courtenay Lai, Ahn Lee, Patrick Chan, Jasmine Chin, Aaron Yamniuk, Kush Dalal, Bryan Barnhart
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Juntao (Matt) Mai, Kate Caldwell, Lindsay DeVorkin, Grace P. Leung, Karine Herve, Yuri Hwang, Cristina Faralla, Wei Wei, Emma Lathouwers, Valentine de Puyraimond, Lauren Clifford, Rhys S. Chappell, Stefan Hannie, Katherine J. Lam, Harveer Dhupar, Tran N. Tran, Melissa Cid, Lena M. Bolten, Tova Pinsky, Ping Xiang, Courteney Lai, Ahn Lee, Vivian Z. Li, Patrick Chan, Jasmine Chin, Steve Booth, Amy C. Lee, Stephanie Masterman, Sherie Duncan, Aaron Yamniuk, Kush Dalal, Tim M. Jacobs, Raffi Tonikian, Bryan C. Barnhart
Publikováno v:
Cancer Research. 83:1886-1886
In this study, we describe the characterization and validation of a diverse panel of fully human CD3-binding antibodies, including hundreds of human and cyno cross-reactive binders. We used two proof-of-concept TCE targets to demonstrate that this pa
Autor:
Lindsay DeVorkin, Tim M. Jacobs, Raffi Tonikian, Karine Hervé, Kate Caldwell, Yuri Hwang, Cristina Faralla, Wei Wei, Katherine J. Lam, Harveer Dhupar, Tran NT Tran, Melissa Cid, Lena M. Bolten, Tova Pinsky, Kush Dalal, Kevin A. Heyries, Bryan C. Barnhart
Publikováno v:
Cancer Research. 82:312-312
Bispecific antibodies that redirect cancer-killing T cells towards tumors are promising next-generation cancer therapies. While there are hundreds of T cell engagers (TCEs) in development, there is only one approved and marketed CD3-binding TCE. The
Autor:
Samuel H. Light, Anna I. Bakardjiev, Gabrielle Rizzuto, Cristina Faralla, Jennifer R. Robbins, Julie A. Theriot, S. Nocadello, Effie Bastounis, Wayne F. Anderson, Fabian E. Ortega
During pregnancy, the placenta protects the fetus against the maternal immune response, as well as bacterial and viral pathogens. Bacterial pathogens that have evolved specific mechanisms of breaching this barrier, such asListeria monocytogenes, pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c1b3505411412b43c2591b271c1726a
Autor:
Robert Janulczyk, Kelly S. Doran, Rong Mu, Cristina Faralla, Kathryn A. Patras, Matteo De Chiara, Alessandro Muzzi, Immaculada Margarit, Matteo M. E. Metruccio, Guido Grandi
Publikováno v:
mBio
mBio, Vol 5, Iss 3 (2014)
mBio, Vol 5, Iss 3 (2014)
Group B Streptococcus (GBS), in the transition from commensal organisms to pathogens, will encounter diverse host environments and, thus, require coordinated control of the transcriptional responses to these changes. This work was aimed at better und
Targeted amino acid substitutions impair streptolysin O toxicity and group A Streptococcus virulence
Autor:
Simona Mangiavacchi, Robert Janulczyk, Simona Tavarini, Emiliano Chiarot, Alessia Corrado, Cristina Faralla, Maria Scarselli, Giovanna Tuscano, Fabiana Falugi, Immaculada Margarit, Daniele Veggi, Giuliano Bensi, Sabrina Capo, Guido Grandi, Nico Chiappini, Elena Cartocci, Annarita Taddei, Gabriella Gambellini
Publikováno v:
Scopus-Elsevier
mBio
mBio, Vol 4, Iss 1 (2013)
mBio
mBio, Vol 4, Iss 1 (2013)
Streptolysin O is a potent pore-forming toxin produced by group A Streptococcus. The aims of the present study were to dissect the relative contributions of different structural domains of the protein to hemolytic activity, to obtain a detoxified for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee1ad2e5b8cf76689f446c00f3d6842b
http://www.scopus.com/inward/record.url?eid=2-s2.0-84878741900&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-84878741900&partnerID=MN8TOARS