Výsledky vyhledávání - "Cristina E. Rodríguez"

Sialic acid removal by trans-sialidase modulates MMP-2 activity during Trypanosoma cruzi infection

Autor: Cristina E. Rodríguez, Alicia Jawerbaum, Oscar Campetella, Martin M. Edreira, Romina Higa, María S. Leguizamón, Daniel Musikant

Publikováno v: Biochimie

Matrix metalloproteinases (MMPs) not only play a relevant role in homeostatic processes but are also involved in several pathological mechanisms associated with infectious diseases. As their clinical relevance in Chagas disease has recently been high

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5e3d6771d3854c91799de5161c1d174
https://doi.org/10.1016/j.biochi.2021.04.005

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Akademický článek

Autophagy Protects from Trastuzumab-Induced Cytotoxicity in HER2 Overexpressing Breast Tumor Spheroids.

Autor: Cristina E Rodríguez, Sara I Reidel, Elisa D Bal de Kier Joffé, Maria A Jasnis, Gabriel L Fiszman

Publikováno v: PLoS ONE, Vol 10, Iss 9, p e0137920 (2015)

Multicellular tumor spheroids represent a 3D in vitro model that mimics solid tumor essential properties including assembly and development of extracellular matrix and nutrient, oxygen and proliferation gradients. In the present study, we analyze the

Externí odkaz: https://doaj.org/article/35a404a3c41846ec9c8f2e29ee2440da

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Breast cancer stem cells are involved in Trastuzumab resistance through the HER2 modulation in 3D culture

Autor: Damian E. Berardi, Laura B. Todaro, Cristina E. Rodríguez, Marianela Abrigo, Elisa Bal de Kier Joffé, Gabriel L. Fiszman

Publikováno v: Journal of Cellular Biochemistry. 119:1381-1391

Breast cancer human cells culture as spheroids develop autophagy and apoptosis, which promotes Trastuzumab resistance in HER2 overexpressing cells. Our aim was to study the association of the hostile environment developed in 3D with the breast cancer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a65a89d4756114c8a1e73e7bcab1b5
https://doi.org/10.1002/jcb.26298

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The Immune System As a New Possible Cell Target for AFP 464 in a Spontaneous Mammary Cancer Mouse Model

Autor: Cristina E. Rodríguez, Elisa Bal de Kier Joffé, Aldana Sólimo, Mariana A. Callero, Andrea I. Loaiza Perez

Publikováno v: Journal of Cellular Biochemistry. 118:2841-2849

Aminoflavone (AFP 464, NSC 710464), an antitumor agent which recently entered phase II clinical trials, acts against estrogen-positive breast cancer (ER+). AFP 464, which has a unique mechanism of action by activating aryl hydrocarbon receptor (AhR)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cc3d0edccb2759d0150fb339c421e982
https://doi.org/10.1002/jcb.25934

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PKCδ Inhibition Impairs Mammary Cancer Proliferative Capacity But Selects Cancer Stem Cells, Involving Autophagy

Autor: Alejandro J. Urtreger, Damian E. Berardi, Laura B. Todaro, Elisa Bal de Kier Joffé, Gabriel L. Fiszman, Stefano M. Cirigliano, María I. Díaz Bessone, Cristina E. Rodríguez, Carolina Flumian

Publikováno v: Journal of Cellular Biochemistry. 117:730-740

Protein kinase C (PKC) is a family of serine/threonine kinases that regulate diverse cellular functions including cell death, proliferation, and survival. Recent studies have reported that PKCδ, are involved in apoptosis or autophagy induction. In t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c4e639ed7d069321748967b39b8d3a8a
https://doi.org/10.1002/jcb.25358

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Autophagy Protects from Trastuzumab-Induced Cytotoxicity in HER2 Overexpressing Breast Tumor Spheroids

Autor: Elisa Bal de Kier Joffé, Gabriel L. Fiszman, Maria A. Jasnis, Cristina E. Rodríguez, Sara I. Reidel

Publikováno v: PLoS ONE
PLoS ONE, 10(9)
Repositorio Institucional del Instituto Nacional de Tecnología Industrial (INTI)
Instituto Nacional de Tecnología Industrial
instacron:INTI
PLoS ONE, Vol 10, Iss 9, p e0137920 (2015)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::968f549634b4b5691af3cf0e103b806e
https://pubmed.ncbi.nlm.nih.gov/26360292

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Abstract 4983: Aminoflavone acts as an immunomodulator of tumor growth in a breast cancer mouse model

Autor: Andrea Irene Loaiza Perez, Cristina E. Rodríguez, Aldana Sólimo, Elisa Bal de Kier Joffé, Mariana A. Callero

Publikováno v: Cancer Research. 76:4983-4983

Aminoflavone (AFP464, NSC 710464), an antitumor agent which recently entered phase II clinical trials, acts against estrogen-positive breast cancer (ER+). AFP464, which has a unique mechanism of action by activating aryl hydrocarbon receptor (AhR) si

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::25782b73edb1f81eaa7415a2c3dc1cb2
https://doi.org/10.1158/1538-7445.am2016-4983

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Abstract 349: Autophagy, cancer stem cells, and trastuzumab resistance in three dimensional cultures of HER2+ breast cancer cells

Autor: Gabriel L. Fiszman, Sara I. Reidel, Maria A. Jasnis, Cristina E. Rodríguez, Elisa Bal de Kier Joffé

Publikováno v: Cancer Research. 75:349-349

HER2 is overexpressed in 20% invasive breast tumors and correlates with low free disease survival. Trastuzumab (Tz), monoclonal antibody anti HER2, is used to treat HER2+ tumors; however more than half of the patients are resistant or acquire resista

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::060cd7001135504d22c29bd96097a7be
https://doi.org/10.1158/1538-7445.am2015-349

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Abstract P5-05-09: Autophagy in three dimensional cultures provides survival advantage against trastuzumab in HER2+ mammary adenocarcinoma cells

Autor: Maria A. Jasnis, Elisa Bal de Kier Joffé, Cristina E. Rodríguez, Gabriel L. Fiszman, Sara Reidel

Publikováno v: Cancer Research. 75:P5-05

HER2 is overexpressed in 20-25% invasive breast tumors, and correlates with low free disease survival. Trastuzumab (Tz), monoclonal antibody anti HER2, is used to treat HER2+ tumors; however more than half of them are resistant or acquire resistance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d8c3b133f4e631ee0745add5c81f19b0
https://doi.org/10.1158/1538-7445.sabcs14-p5-05-09

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Abstract 226: Trastuzumab effect on cell death and proliferation of HER2+ mammary adenocarcinoma cells using a tridimensional culture

Autor: Gabriel L. Fiszman, Luciana M. Moverer, Maria A. Jasnis, Sara Reidel, Lina Marino, Elisa Bal de Kier Joffé, Cristina E. Rodríguez

Publikováno v: Cancer Research. 73:226-226

HER2 is overexpressed in 20-25% invasive breast tumors, and associated with low free disease survival. Trastuzumab (Tz), monoclonal antibody anti HER2, is used as immunotherapy to treat HER2+ tumors; however more than half of them are resistant or ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a06ae4e44b81014544ddad755905bcde
https://doi.org/10.1158/1538-7445.am2013-226

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