Neural substrates of cognitive impairment in a NMDAR hypofunction mouse model of schizophrenia and partial rescue by risperidone

Autor: Cristina Delgado-Sallent, Thomas Gener, Pau Nebot, Cristina López-Cabezón, M. Victoria Puig

Publikováno v: Frontiers in Cellular Neuroscience, Vol 17 (2023)

N-methyl D-aspartate receptor (NMDAR) hypofunction is a pathophysiological mechanism relevant for schizophrenia. Acute administration of the NMDAR antagonist phencyclidine (PCP) induces psychosis in patients and animals while subchronic PCP (sPCP) pr

Externí odkaz: https://doaj.org/article/9c9e714f752d459d86afef747b55b3b6

Reversible photocontrol of dopaminergic transmission in wild-type animals

Autor: Carlo Matera, Pablo Calvé, Verònica Casadó-Anguera, Rosalba Sortino, Alexandre M. J. Gomila, Estefanía Moreno, Thomas Gener, Cristina Delgado-Sallent, Pau Nebot, Davide Costazza, Sara Conde-Berriozabal, Mercè Masana, Jordi Hernando, Vicent Casadó, M. Victoria Puig, Pau Gorostiza

Publikováno v: ORCID
International Journal of Molecular Sciences; Volume 23; Issue 17; Pages: 10114
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Dipòsit Digital de la UB
Universidad de Barcelona

Understanding the dopaminergic system is a priority in neurobiology and neuropharmacology. Dopamine receptors are involved in the modulation of fundamental physiological functions, and dysregulation of dopaminergic transmission is associated with maj

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::921d906e8fe6bf668fc1abf5545eb3ce
https://doi.org/10.26434/chemrxiv-2022-8jlxp

Serotonin 5-HT

Autor: Thomas, Gener, Adrià, Tauste Campo, Maria, Alemany-González, Pau, Nebot, Cristina, Delgado-Sallent, Jordi, Chanovas, M Victoria, Puig

Publikováno v: Neuropharmacology. 158

Atypical antipsychotic drugs (APDs) used to treat positive and negative symptoms in schizophrenia block serotonin receptors 5-HT

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e40a3a0cab7444ab65d623cfa89650e4
https://pubmed.ncbi.nlm.nih.gov/31430459

Serotonin 5-HT1A receptors modulate neural rhythms in prefrontal cortex and hippocampus and prefronto-hippocampal connectivity in alert mice

Autor: Thomas Gener, Maria Victoria Puig, Maria Alemany-González, Cristina Delgado-Sallent, Adrià Tauste-Campo

Publikováno v: Advances in Cognitive Neurodynamics (VI) ISBN: 9789811088537

Theserotonergic system plays a crucial role in cognition and is a target of many psychiatric treatments. In particular, serotonin 5-HT1A receptors (5-HT1AR) in the prefrontal cortex and hippocampus play key roles in learning, memory, behavioral flexi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b24984813619fd9e1ea3dcf314a47aaf
https://hdl.handle.net/2117/380478