Orexin/Hypocretin and MCH Neurons: Cognitive and Motor Roles Beyond Arousal

Autor: Cristina Concetti, Denis Burdakov

Publikováno v: Frontiers in Neuroscience, Vol 15 (2021)

The lateral hypothalamus (LH) is classically implicated in sleep-wake control. It is the main source of orexin/hypocretin and melanin-concentrating hormone (MCH) neuropeptides in the brain, which have been both implicated in arousal state switching.

Externí odkaz: https://doaj.org/article/5376bcba43cf4c9e824ae130603c1686

Control of fear extinction by hypothalamic melanin-concentrating hormone-expressing neurons

Autor: Cristina Concetti, Daria Peleg-Raibstein, Denis Burdakov, Edward F. Bracey

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 117 (36)

Learning to fear danger is essential for survival. However, overactive, relapsing fear behavior in the absence of danger is a hallmark of disabling anxiety disorders that affect millions of people. Its suppression is thus of great interest, but the n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d18af84228bd31100ef51a35257be19
https://pubmed.ncbi.nlm.nih.gov/32848057

Temporal plasticity of apical progenitors in the developing mouse neocortex

Autor: Natalia Baumann, Sabine Fievre, Cristina Concetti, Giorgia Bartolini, Polina Oberst, Denis Jabaudon

Publikováno v: Nature, Vol. 573, No 7774 (2019) pp. 370-374

The diverse subtypes of excitatory neurons that populate the neocortex are born from apical progenitors located in the ventricular zone. During corticogenesis, apical progenitors sequentially generate deep-layer neurons followed by superficial-layer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e036bacb50305732e40293f1d2a72d60
https://pubmed.ncbi.nlm.nih.gov/32350465