Hyaluronic Acid-Based Nanosystems for CD44 Mediated Anti-Inflammatory and Antinociceptive Activity

Autor: Saniya Salathia, Maria Rosa Gigliobianco, Cristina Casadidio, Piera Di Martino, Roberta Censi

Publikováno v: International Journal of Molecular Sciences. 24:7286

The nervous and immune systems go hand in hand in causing inflammation and pain. However, the two are not mutually exclusive. While some diseases cause inflammation, others are caused by it. Macrophages play an important role in modulating inflammati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d73ba0a184c83a3bad28d82aff5a2a74
https://doi.org/10.3390/ijms24087286

Hot Melt Extrusion: Highlighting Physicochemical Factors to Be Investigated While Designing and Optimizing a Hot Melt Extrusion Process

Autor: Roberta Censi, Maria Rosa Gigliobianco, Cristina Casadidio, Piera Di Martino

Publikováno v: Pharmaceutics, Vol 10, Iss 3, p 89 (2018)

Hot-melt extrusion (HME) is a well-accepted and extensively studied method for preparing numerous types of drug delivery systems and dosage forms. It offers several advantages: no solvents are required, it is easy to scale up and employ on the indust

Externí odkaz: https://doaj.org/article/3fc74076c7fe40a1a1780a69533464f5

Interpenetrating Hydrogel Networks Enhance Mechanical Stability, Rheological Properties, Release Behavior and Adhesiveness of Platelet-Rich Plasma

Autor: Piera Di Martino, Siyuan Deng, Cristina Casadidio, Roberta Censi, Fulvio Laus, Maria Giovanna Sabbieti, Dimitrios Agas, Maria Rosa Gigliobianco

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 4, p 1399 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 4

Platelet‐rich plasma (PRP) has attracted much attention for the treatment of articular cartilagedefects or wounds due to its intrinsic content of growth factors relevant for tissue repair. However, the shortresidence time of PRP in vivo, due to the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec25f24dc356258ed7d2259141d42576
https://doi.org/10.3390/ijms21041399

Daptomycin-loaded biodegradable thermosensitive hydrogels enhance drug stability and foster bactericidal activity against Staphylococcus aureus

Autor: Maria Eugenia Butini, Roberta Censi, Piera Di Martino, Mariagrazia Di Luca, Cristina Casadidio, Andrej Trampuz

Publikováno v: European journal of pharmaceutics and biopharmaceutics 130 (2018): 260–271. doi:10.1016/j.ejpb.2018.07.001
info:cnr-pdr/source/autori:Casadidio C.; Butini M.E.; Trampuz A.; Di Luca M.; Censi R.; Di Martino P./titolo:Daptomycin-loaded biodegradable thermosensitive hydrogels enhance drug stability and foster bactericidal activity against Staphylococcus aureus/doi:10.1016%2Fj.ejpb.2018.07.001/rivista:European journal of pharmaceutics and biopharmaceutics/anno:2018/pagina_da:260/pagina_a:271/intervallo_pagine:260–271/volume:130
European Journal of Pharmaceutics and Biopharmaceutics

A drug delivery system based on fully biodegradable thermosensitive hydrogels enabling controlled antibiotic release may support the management of implant-associated infections. In this work, the lipopeptide antibiotic daptomycin was encapsulated in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edcae041d96d7305c6f3ddb8c6971024
http://hdl.handle.net/11581/409186

Nanocrystals of Poorly Soluble Drugs: Drug Bioavailability and Physicochemical Stability

Autor: Roberta Censi, Piera Di Martino, Cristina Casadidio, Maria Rosa Gigliobianco

Publikováno v: Pharmaceutics, Vol 10, Iss 3, p 134 (2018)
Pharmaceutics

Many approaches have been developed over time to overcome the bioavailability limitations of poorly soluble drugs. With the advances in nanotechnology in recent decades, science and industry have been approaching this issue through the formulation of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79bd6012b8a0b68ec2364042d213115a