Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Cristina Bolzati"'
Autor:
Cristina Bolzati, Carolina Gobbi, Guillermina Ferro-Flores, Sofia Turato, Blanca Ocampo-Garcia, Debora Carpanese, Cristina Marzano, Barbara Spolaore, Giulio Fracasso, Antonio Rosato, Laura Meléndez-Alafort
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 492 (2023)
Previously, we demonstrated that the 177Lu-labeled single-chain variable fragment of an anti-prostate-specific membrane antigen (PSMA) IgG D2B antibody (scFvD2B) showed higher prostate cancer (PCa) cell uptake and tumor radiation doses compared to 17
Externí odkaz:
https://doaj.org/article/bb6461fa297a46f4943826c05c663bb6
Autor:
Debora Carpanese, Guillermina Ferro-Flores, Blanca Ocampo-Garcia, Clara Santos-Cuevas, Nicola Salvarese, Mariangela Figini, Giulio Fracasso, Laura De Nardo, Cristina Bolzati, Antonio Rosato, Laura Meléndez-Alafort
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract The clinical translation of theranostic 177Lu-radiopharmaceuticals based on inhibitors of the prostate-specific membrane antigen (PSMA) has demonstrated positive clinical responses in patients with advanced prostate cancer (PCa). However, ch
Externí odkaz:
https://doaj.org/article/9b2d1ad6b66740dab5e3f6564255938b
Publikováno v:
Molecules, Vol 28, Iss 3, p 1487 (2023)
The β− emitter, rhenium-188 (188Re), has long been recognized as an attractive candidate for targeted cancer radionuclide therapy (TRNT). This transition metal shares chemical similarities with its congener element technetium, whose nuclear isomer
Externí odkaz:
https://doaj.org/article/3218b1147d114d3881b39675b5e01c23
Autor:
Nicola Salvarese, Debora Carpanese, Laura Meléndez-Alafort, Laura De Nardo, Andrea Calderan, Barbara Biondi, Paolo Ruzza, Antonio Rosato, Cristina Bolzati
Publikováno v:
Molecules, Vol 27, Iss 8, p 2548 (2022)
Background: The [99mTc][Tc(N)(PNP)] system, where PNP is a bisphosphinoamine, is an interesting platform for the development of tumor ‘receptor-specific’ agents. Here, we compared the reactivity and impact of three [Tc(N)(PNP)] frameworks on the
Externí odkaz:
https://doaj.org/article/624b5dfef7824c07b6bc0cf22645f34f
Autor:
Sara Brunello, Nicola Salvarese, Debora Carpanese, Carolina Gobbi, Laura Melendez-Alafort, Cristina Bolzati
Publikováno v:
Molecules, Vol 27, Iss 9, p 2617 (2022)
Recently, prostate-specific membrane antigen (PSMA) has gained momentum in tumor nuclear molecular imaging as an excellent target for both the diagnosis and therapy of prostate cancer. Since 2008, after years of preclinical research efforts, a plenti
Externí odkaz:
https://doaj.org/article/f336efa2ba0042f4a15569a5cc37cbba
Autor:
Cristina Bolzati, Barbara Spolaore
Publikováno v:
Molecules, Vol 26, Iss 12, p 3492 (2021)
Site-specific conjugation of proteins is currently required to produce homogenous derivatives for medicine applications. Proteins derivatized at specific positions of the polypeptide chain can actually show higher stability, superior pharmacokinetics
Externí odkaz:
https://doaj.org/article/88d009137e9140a5b29c8e065516a792
Autor:
Cristina Bolzati, Alessandro Dolmella
Publikováno v:
Inorganics, Vol 8, Iss 1, p 3 (2019)
The knowledge on element 43 (Tc) of the periodic table, built over the years through the contributions given by the close relationship between chemistry and nuclear medicine, allowed the development of new and increasingly effective radiopharmaceutic
Externí odkaz:
https://doaj.org/article/392b3137ed1b4d39b18a7d8bd2688aad
In this work, we explored the ability of N-methyl-S-methyl dithiocarbazate ([H2N-N(CH3)C(=S)SCH3]; DTCZ) to form coordination complexes with copper starting from different copper (II, I) sources. Data proved that the type of used salt affects the sto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::969806c6976f1965f4ad43416f902b2f
https://doi.org/10.26434/chemrxiv-2023-gxkj5
https://doi.org/10.26434/chemrxiv-2023-gxkj5
Autor:
Cristina Bolzati, Nicola Salvarese, Barbara Spolaore, Andrea Vittadini, Daniel Forrer, Sara Brunello, Simona Ghiani, Alessandro Maiocchi
Publikováno v:
Molecular Pharmaceutics. 19:876-894
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c27679e445e0fcf158c390c329dd85f
https://doi.org/10.1021/acs.molpharmaceut.1c00816
https://doi.org/10.1021/acs.molpharmaceut.1c00816
The β- emitter, rhenium-188 (188Re), has long been recognized as an attractive candidate for targeted cancer radionuclide therapy (TRNT). This transition metal shares chemical similarities with its congener element technetium, whose nuclear isomer t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acdee5c86434758fc9b5f447f4d12de8
https://lirias.kuleuven.be/handle/20.500.12942/716336
https://lirias.kuleuven.be/handle/20.500.12942/716336