Zobrazeno 1 - 10 of 89 pro vyhledávání: '"Cristina Avonto"'
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Akademický článek
Identification of Potential Skin Sensitizers in Myrrh
Autor: Qi Zhou, Yongbei Liu, Yanran Tang, Yalda Shokoohinia, Amar G. Chittiboyina, Mei Wang, Cristina Avonto
Publikováno v: Cosmetics, Vol 6, Iss 3, p 47 (2019)
The exudate of Commiphora myrrha (myrrh) has been known for centuries as one of the most popular natural skin remedies. The characterization and safety assessment of myrrh ingredients are challenging due to the chemical variability of commercially av
Externí odkaz: https://doaj.org/article/3a3a291c7eb54479ad3bf203c46cd915
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5
Is Isoeugenol a Prehapten? Characterization of a Thiol-Reactive Oxidative Byproduct of Isoeugenol and Potential Implications for Skin Sensitization
Autor: Amar G. Chittiboyina, Jongmin Ahn, Cristina Avonto, Ikhlas A. Khan
Publikováno v: Chemical Research in Toxicology. 33:948-954
Isoeugenol is widely used by the cosmetic and fragrance industries, but it also represents a known cause of skin sensitization adverse effects. Although devoid of a structural alert, isoeugenol has been classified as prehapten in virtue of the presen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f96aef4e5f3d40d1268ba76c824f7381
https://doi.org/10.1021/acs.chemrestox.9b00501
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6
Solvents effect on dansyl cysteamine depletion and reactivity classification of skin sensitizers: Tackling the challenges using binary solvent systems
Autor: Cristina Avonto, Amar G. Chittiboyina, Jongmin Ahn, Ikhlas A. Khan
Publikováno v: Journal of pharmacological and toxicological methods. 112
The high throughput method using dansyl cysteamine (HTS-DCYA™) is a sensitive and rapid in chemico approach to characterize skin sensitizers' thio-reactivity. The direct quantification of fluorescent hapten-DCYA adducts facilitates the rapid testin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed216e18bdd9a3801fac34a182dafd8b
https://pubmed.ncbi.nlm.nih.gov/34403747
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Are atranols the only skin sensitizers in oakmoss? A systematic investigation using non-animal methods
Autor: Mei Wang, Ikhlas A. Khan, Amar G. Chittiboyina, Olivia R. Dale, Shabana I. Khan, Jon F. Parcher, Cristina Avonto
Publikováno v: Toxicology in vitro : an international journal published in association with BIBRA. 70
Oakmoss and treemoss absolutes are the major natural extracts of concern as potential sources of skin sensitizers in cosmetics and personal care products (PCP). Two single constituents, atranol and chloroatranol, have been identified as primary culpr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfec34a42ddb976834a0c4ef8fe177a1
https://pubmed.ncbi.nlm.nih.gov/33212168
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8
Thiol-trapping natural products under the lens of the cysteamine assay: friends, foes, or simply alternatively reversible ligands?
Autor: Orazio Taglialatela-Scafati, Cristina Avonto, Diego Caprioglio, Giovanni Appendino, Alberto Minassi
The literature on thia-Michael acceptors is vast and can be cherry-picked to show either that these compounds pollute chemical libraries displaying unselective binding and propensity to toxicity, or, alternatively, that the thiol-trapping reaction is
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2672d1d07527f3dc9905baf4702edad
http://hdl.handle.net/11588/826620
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9
Discovery of a Remarkable Methyl Shift Effect in the Vanilloid Activity of Triterpene Amides
Autor: Giovanni Appendino, Aniello Schiano Moriello, Pietro Amodeo, Luciano De Petrocellis, Rosa Maria Vitale, Danilo Del Prete, Cristina Avonto
Publikováno v: Journal of natural products
(2020). doi:10.1021/acs.jnatprod.0c00639
info:cnr-pdr/source/autori:Vitale R.M.; Avonto C.; Del Prete D.; Moriello A.S.; Amodeo P.; Appendino G.; De Petrocellis L./titolo:Discovery of a Remarkable Methyl Shift Effect in the Vanilloid Activity of Triterpene Amides/doi:10.1021%2Facs.jnatprod.0c00639/rivista:Journal of natural products (Print)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume
Journal of Natural Products
As part of a study on triterpenoid conjugates, the dietary pentacyclic triterpenoids oleanolic (2a) and ursolic acids (3a) were coupled with vanillamine, and the resulting amides (2b and 3b, respectively) were assayed for activity on the vanilloid re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dcee1cf07aa7015648503d8935d4d27
http://www.cnr.it/prodotto/i/438893
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10
In chemico assessment of potential sensitizers: Stability and direct peptide reactivity of 24 fragrance ingredients
Autor: Cristina Avonto, Yan-Hong Wang, Ikhlas A. Khan, Amar G. Chittiboyina, Stanislav Vukmanovic
Publikováno v: Journal of Applied Toxicology. 39:398-408
Twenty-four pure fragrance ingredients of concern as potential skin sensitizers were previously subjected to degradation studies and evaluated using the high throughput with dansyl cysteamine (HTS-DCYA) method. The experimental results showed that tw
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::94b2c14e69c08adf1669da5438753794
https://doi.org/10.1002/jat.3732
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