Streaming histogram sketching for rapid microbiome analytics

Autor: Will PM Rowe, Anna Paola Carrieri, Cristina Alcon-Giner, Shabhonam Caim, Alex Shaw, Kathleen Sim, J. Simon Kroll, Lindsay J. Hall, Edward O. Pyzer-Knapp, Martyn D. Winn

Publikováno v: Microbiome, Vol 7, Iss 1, Pp 1-13 (2019)

Abstract Background The growth in publically available microbiome data in recent years has yielded an invaluable resource for genomic research, allowing for the design of new studies, augmentation of novel datasets and reanalysis of published works.

Externí odkaz: https://doaj.org/article/973d8e994df64aea9c28f962db7801ac

Optimisation of 16S rRNA gut microbiota profiling of extremely low birth weight infants

Autor: Cristina Alcon-Giner, Shabhonam Caim, Suparna Mitra, Jennifer Ketskemety, Udo Wegmann, John Wain, Gusztav Belteki, Paul Clarke, Lindsay J. Hall

Publikováno v: BMC Genomics, Vol 18, Iss 1, Pp 1-15 (2017)

Abstract Background Infants born prematurely, particularly extremely low birth weight infants (ELBW) have altered gut microbial communities. Factors such as maternal health, gut immaturity, delivery mode, and antibiotic treatments are associated with

Externí odkaz: https://doaj.org/article/7a0b0dbd079d424abb11530440702909

A novel bacteriocin produced by Bifidobacterium longum subsp. infantis has dual antimicrobial and immunomodulatory activity

Autor: Sree Gowrinadh Javvadi, Magdalena Kujawska, Diana Papp, Aleksander M Gontarczyk, Anne Jordan, Melissa A.E. Lawson, Ian J. O’Neill, Cristina Alcon-Giner, Raymond Kiu, Paul Clarke, Naiara Beraza, Lindsay J Hall

Bacteriocins are ribosomally-synthesized antimicrobial peptides produced by bacteria with either narrow or broad spectrum activity. Many genome mining studies have indicated that bacteriocin gene clusters are widespread within certain gut microbiota

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b14a53ab086e513ce870f851f1112b2d
https://doi.org/10.1101/2022.01.27.477972

Antibiotic-induced disturbances of the gut microbiota result in accelerated breast tumor growth

Autor: Rebecca Ansorge, Matthew Madgwick, Melanie R. Rutkowski, Matthew J. Dalby, Anna Andrusaite, Charlotte Leclaire, Tzu-Yu Feng, Martina Di Modica, Benjamin Kirkup, Gwénaëlle Le Gall, Kate A Makin, Alastair M. McKee, Jack Paveley, Shabhonam Caim, Sally A. Dreger, Wesley J. Fowler, Elda Tagliabue, Cristina Alcon-Giner, Tiziana Triulzi, Lindsay J. Hall, Simon Milling, Stephen D. Robinson, Katherine N. Weilbaecher, Christopher A. Price, Tamas Korcsmaros

Publikováno v: iScience
McKee, A M, Hall, L J & Robinson, S D 2021, ' Antibiotic-induced disturbances of the gut microbiota result in accelerated breast tumor growth ', iScience, vol. 24, no. 9, 103012 . https://doi.org/10.1016/j.isci.2021.103012
iScience, Vol 24, Iss 9, Pp 103012-(2021)

Summary The gut microbiota’s function in regulating health has seen it linked to disease progression in several cancers. However, there is limited research detailing its influence in breast cancer (BrCa). This study found that antibiotic-induced pe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e96dca44a920165f8339dbc6665dce74
https://ueaeprints.uea.ac.uk/id/eprint/81026/

Microbiota supplementation with Bifidobacterium and Lactobacillus modifies the preterm infant gut microbiota and metabolome: an observational study

Autor: Jennifer Ketskemety, Raymond Kiu, Gustav Belteki, Suparna Mitra, Lindsay J. Hall, Charlotte Leclaire, Jonathan R. Swann, Magdalena Kujawska, Lisa Chalklen, Fahmina Fardus-Reid, Kathleen Sim, Matthew J. Dalby, Melissa A. E. Lawson, Cristina Alcon-Giner, Katherine McColl, Alexander G. Shaw, Paul Clarke, J. Simon Kroll, Shabhonam Caim

Publikováno v: Cell Reports Medicine, Vol 1, Iss 5, Pp 100077-(2020)

Summary: Supplementation with members of the early-life microbiota as “probiotics” is increasingly used in attempts to beneficially manipulate the preterm infant gut microbiota. We performed a large observational longitudinal study comprising two

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::471e73830029490634043312d1f9fdb0
http://hdl.handle.net/10044/1/82162