Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Cristina, Puigjaner"'
Autor:
Claudi de Rocafiguera, Blanca Belsa, Mercè Font-Bardia, Cristina Puigjaner, Eduard Serra, Ana M. Cuartero-Albesa, Raimon Puig de la Bellacasa, José I. Borrell
Publikováno v:
Pharmaceuticals, Vol 17, Iss 3, p 284 (2024)
The impact of the crystalline or amorphous structure of a solid on the solubility and pharmacokinetic properties of a drug candidate is always considered by the pharmaceutical industry during the development of a new drug; however, it is not so frequ
Externí odkaz:
https://doaj.org/article/f74ee6daa76443219fb465642c9a1c43
Publikováno v:
Crystals, Vol 11, Iss 4, p 342 (2021)
The knowledge about the solid forms landscape of Bilastine (BL) has been extended. The crystal structures of two anhydrous forms have been determined, and the relative thermodynamic stability among the three known anhydrous polymorphs has been establ
Externí odkaz:
https://doaj.org/article/ebb592d0159e4171ac4fc3cb69052388
Publikováno v:
Acta Crystallographica Section B Structural Science, Crystal Engineering and Materials. 78:253-260
The first crystal structure of a fully N-alkylated diindolocarbazole derivative, namely, 5,8,14-tributyldiindolo[3,2-b;2′,3′-h]carbazole (1, C36H39N3), has been determined from laboratory powder X-ray diffraction (PXRD) data. A complex trigonal s
Autor:
Raimon Puig de la Bellacasa, José I. Borrell, Xavier Batllori, Jordi Teixidó, Oriol Vallcorba, Claudi de Rocafiguera, Raül Ondoño, Iñaki Galve, Cristina Puigjaner, Mercè Font-Bardia
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Universidad de Barcelona
Wheland intermediates are usually unstable compounds and only a few have been isolated at very low temperatures. During our work on tyrosine kinase inhibitors, we studied the bromination of 7 in order to obtain a dibromo substituted pyrido[2,3-d]pyri
Publikováno v:
Crystals
Volume 11
Issue 4
Dipòsit Digital de la UB
Universidad de Barcelona
Crystals, Vol 11, Iss 342, p 342 (2021)
Volume 11
Issue 4
Dipòsit Digital de la UB
Universidad de Barcelona
Crystals, Vol 11, Iss 342, p 342 (2021)
The knowledge about the solid forms landscape of Bilastine (BL) has been extended. The crystal structures of two anhydrous forms have been determined, and the relative thermodynamic stability among the three known anhydrous polymorphs has been establ
Autor:
Iñaki, Galve, Raül, Ondoño, Claudi, de Rocafiguera, Raimon, Puig de la Bellacasa, Xavier, Batllori, Cristina, Puigjaner, Mercè, Font-Bardia, Oriol, Vallcorba, Jordi, Teixidó, José I, Borrell
Publikováno v:
Organicbiomolecular chemistry. 18(48)
Wheland intermediates are usually unstable compounds and only a few have been isolated at very low temperatures. During our work on tyrosine kinase inhibitors, we studied the bromination of 7 in order to obtain a dibromo substituted pyrido[2,3-d]pyri
Autor:
Cristina Puigjaner, Roger Estrada-Tejedor, Santiago Ramón y Cajal, Arnau Plans, Antoni Torres-Coll, Nieves Rodríguez-Picazo, Jordi Teixidó, José I. Borrell, Mercè Font-Bardia, Elisabeth Bou-Petit
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Universidad de Barcelona
Pyrazol-3-amine is a scaffold present in a large number of compounds with a wide range of biological activities and, in many cases, the heterocycle is C4–C5 fused to a second ring. Among the different reactions used for the decoration of the pyrazo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b160b8fe84427f9e270126a8493919d
http://hdl.handle.net/2445/175625
http://hdl.handle.net/2445/175625
Publikováno v:
Molecular Pharmaceutics. 15:1909-1916
An in-depth analysis of the solid forms of the anticoagulant drug Apixaban (APX) has been conducted to sort out the confusion in the scientific and patent literature regarding the solid forms landscape. The nomenclature employed and the accompanying
Autor:
Santiago Ramón y Cajal, Raimon Puig de la Bellacasa, Xavier Batllori, Nabí Ferrer, Jordi Teixidó, Cristina Puigjaner, Roger Estrada-Tejedor, Elsa Picas, Julià Sempere, Elisabeth Bou-Petit, José I. Borrell, Mercè Font-Bardia
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Universidad de Barcelona
The reaction between pyridones (1) and substituted hydrazines 4 can afford two different regioisomeric pyrazolo[3,4-b]pyridin - 6-ones 2 and 3 depending on the initial substitution of the methoxy group and the direction of the cyclization. In the cas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5072bb39d345824dcd5e5cafb7106a04
http://hdl.handle.net/2445/163391
http://hdl.handle.net/2445/163391
Publikováno v:
CrystEngComm. 16:8214-8223
An experimental and computational study of the polymorphism of o-nitrophenyldiphenylphosphine oxide (1) has been carried out. Two polymorphs of 1 have been obtained after a comprehensive screening procedure and their structures have been determined b