Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Cristina, Olivieri"'
Autor:
Jian Wu, Nisha A Jonniya, Sophia P Hirakis, Cristina Olivieri, Gianluigi Veglia, Alexandr P Kornev, Susan S Taylor
Publikováno v:
eLife, Vol 12 (2024)
Although the αC-β4 loop is a stable feature of all protein kinases, the importance of this motif as a conserved element of secondary structure, as well as its links to the hydrophobic architecture of the kinase core, has been underappreciated. We f
Externí odkaz:
https://doaj.org/article/d95e3a9288ba4ee1888840bfdd411ffc
Autor:
Cristina Olivieri, Yingjie Wang, Caitlin Walker, Manu Veliparambil Subrahmanian, Kim N Ha, David Bernlohr, Jiali Gao, Carlo Camilloni, Michele Vendruscolo, Susan S Taylor, Gianluigi Veglia
Publikováno v:
eLife, Vol 12 (2024)
Allosteric cooperativity between ATP and substrates is a prominent characteristic of the cAMP-dependent catalytic subunit of protein kinase A (PKA-C). This long-range synergistic action is involved in substrate recognition and fidelity, and it may al
Externí odkaz:
https://doaj.org/article/97f7a7bc79034a6aaaaa8c648397a2b6
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Nuclear magnetic resonance (NMR) spectroscopy is a powerful high-resolution tool for characterizing biomacromolecular structure, dynamics, and interactions. However, the lengthy longitudinal relaxation of the nuclear spins significantly exte
Externí odkaz:
https://doaj.org/article/d2548c32c7ba46419c1e2861249f073b
Autor:
Cristina Olivieri, Caitlin Walker, Adak Karamafrooz, Yingjie Wang, V. S. Manu, Fernando Porcelli, Donald K. Blumenthal, David D. Thomas, David A. Bernlohr, Simon M. Sandford, Susan S. Taylor, Gianluigi Veglia
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Olivieri, Walker, Karamafrooz et al. show that the fusion of the dynamic J-domain to PKA-C (PKA-CDNAJB1) disrupts the internal allosteric network, attenuating the nucleotide/PKI binding cooperativity. This study suggests that the reduced allosteric c
Externí odkaz:
https://doaj.org/article/43c1fcd3a0854b83a040ab4779192c9e
Autor:
Gian Luigi Gonnella, Pietro Paolo Giuri, Bruno Antonio Zanfini, Matteo Biancone, Luciano Frassanito, Cristina Olivieri, Gaetano Draisci
Publikováno v:
Brazilian Journal of Anesthesiology, Vol 71, Iss 2, Pp 178-180 (2021)
Cardiofaciocutaneous syndrome is a rare syndrome characterized by particular craniofacial features, cardiac abnormalities, and multiple organ diseases. Patients present with pulmonary stenosis, hypertrophic cardiomyopathy, short neck, micrognathia, l
Externí odkaz:
https://doaj.org/article/db9861b711494988b6332aed45f4e5be
Autor:
Cristina Olivieri, Caitlin Walker, Manu Veliparambil Subrahmanian, Fernando Porcelli, Susan S. Taylor, David A. Bernlohr, Gianluigi Veglia
Publikováno v:
FEBS Letters. 597:1055-1072
Autor:
Cristina Olivieri, Yingjie Wang, Geoffrey C Li, Manu V S, Jonggul Kim, Benjamin R Stultz, Matthew Neibergall, Fernando Porcelli, Joseph M Muretta, David DT Thomas, Jiali Gao, Donald K Blumenthal, Susan S Taylor, Gianluigi Veglia
Publikováno v:
eLife, Vol 9 (2020)
In the nucleus, the spatiotemporal regulation of the catalytic subunit of cAMP-dependent protein kinase A (PKA-C) is orchestrated by an intrinsically disordered protein kinase inhibitor, PKI, which recruits the CRM1/RanGTP nuclear exporting complex.
Externí odkaz:
https://doaj.org/article/34c13da9463648a9980c22009c9c1bf8
Autor:
Claudia Carmassi, Camilla Gesi, Martina Corsi, Ivan M. Cremone, Carlo A. Bertelloni, Enrico Massimetti, Maria Cristina Olivieri, Ciro Conversano, Massimo Santini, Liliana Dell’Osso
Publikováno v:
Annals of General Psychiatry, Vol 17, Iss 1, Pp 1-7 (2018)
Abstract Background Emergency services personnel face frequent exposure to potentially traumatic events, with the potential for chronic symptomatic distress. The DSM-5 recently recognized a particular risk for post-traumatic stress disorder (PTSD) am
Externí odkaz:
https://doaj.org/article/add144a670d4481e8e58fdc8a1112d0c
Publikováno v:
Journal of Biomolecular NMR. 77:1-14
The nuclear Overhauser effect (NOE) is one of NMR spectroscopy's most important and versatile parameters. NOE is routinely utilized to determine the structures of medium-to-large size biomolecules and characterize protein-protein, protein-RNA, protei
Autor:
Cristina Olivieri, Caitlin Walker, Adak Karamafrooz, Yingjie Wang, V. S. Manu, Fernando Porcelli, Donald K. Blumenthal, David D. Thomas, David A. Bernlohr, Sanford M. Simon, Susan S. Taylor, Gianluigi Veglia
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-1 (2021)
A Correction to this paper has been published: https://doi.org/10.1038/s42003-021-02006-3
Externí odkaz:
https://doaj.org/article/7c24fd9db8f04d64a2a736102b658354