Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Cristina, Megino"'
Autor:
Gisela Altés, Anna Olomí, Aida Perramon-Güell, Sara Hernández, Anna Casanovas, Aurora Pérez, Juan Miguel Díaz-Tocados, José Manuel Valdivielso, Cristina Megino, Raúl Navaridas, Xavier Matias-Guiu, Ophir D. Klein, Joaquim Egea, Xavi Dolcet, Andrée Yeramian, Mario Encinas
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Genes of the Sprouty family (Spry1-4) are feedback inhibitors of receptor tyrosine kinases, especially of Ret and the FGF receptors. As such, they play distinct and overlapping roles in embryo morphogenesis and are considered to be tumor sup
Externí odkaz:
https://doaj.org/article/c35f82b053404988a6db6232e37d7598
Autor:
Michelle Maurin, Mohammadreza Ranjouri, Cristina Megino-Luque, Justin Y. Newberg, Dongliang Du, Katelyn Martin, Robert E. Miner, Mollie S. Prater, Dave Keng Boon Wee, Barbara Centeno, Shondra M. Pruett-Miller, Paul Stewart, Jason B. Fleming, Xiaoqing Yu, Jose Javier Bravo-Cordero, Ernesto Guccione, Michael A. Black, Karen M. Mann
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract RNA splicing is an important biological process associated with cancer initiation and progression. However, the contribution of alternative splicing to pancreatic cancer (PDAC) development is not well understood. Here, we identify an enrichm
Externí odkaz:
https://doaj.org/article/0792cf6371164a1eae6f885ff6f53bed
Autor:
Raúl Navaridas, Maria Vidal‐Sabanés, Anna Ruiz‐Mitjana, Aida Perramon‐Güell, Cristina Megino‐Luque, David Llobet‐Navas, Xavier Matias‐Guiu, Joaquim Egea, Mario Encinas, Lídia Bardia, Julien Colombelli, Xavier Dolcet
Publikováno v:
Cancer Communications, Vol 43, Iss 5, Pp 620-624 (2023)
Externí odkaz:
https://doaj.org/article/07b55548b70041ffb7bc3d9db626bcb2
Autor:
Cristina Megino‐Luque, Pol Sisó, Natalia Mota‐Martorell, Raúl Navaridas, Inés de laRosa, Izaskun Urdanibia, Manel Albertí‐Valls, Maria Santacana, Miquel Pinyol, Núria Bonifaci, Anna Macià, David Llobet‐Navas, Sònia Gatius, Xavier Matias‐Guiu, Núria Eritja
Publikováno v:
Molecular Oncology, Vol 16, Iss 11, Pp 2235-2259 (2022)
AT‐rich interactive domain‐containing protein 1A (ARID1A) loss‐of‐function mutation accompanied by a loss of ARID1A protein expression is frequently observed in endometrial carcinomas. However, the molecular mechanisms linking these genetic c
Externí odkaz:
https://doaj.org/article/88829f0c96d5428fb487eeec1a5e9881
AT-rich interactive domain-containing protein 1A (ARID1A) loss-of-function mutation accompanied by a loss of ARID1A protein expression is frequently observed in endometrial carcinomas (EC). However, the mechanisms underlying this loss of ARID1A invol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed21950d8e9117ba02d7f22bde8c00dc
https://doi.org/10.1101/2022.12.14.520528
https://doi.org/10.1101/2022.12.14.520528
Autor:
Sònia Gatius, Mariona Jove, Cristina Megino-Luque, Manel Albertí-Valls, Andree Yeramian, Nuria Bonifaci, Miquel Piñol, Maria Santacana, Irene Pradas, David Llobet-Navas, Reinald Pamplona, Xavier Matías-Guiu, Núria Eritja
Publikováno v:
Cancers; Volume 14; Issue 12; Pages: 2842
Metabolomic profiling analysis has the potential to highlight new molecules and cellular pathways that may serve as potential therapeutic targets for disease treatment. In this study, we used an LC-MS/MS platform to define, for the first time, the sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c203d989e3dcc86de3239e0e4085fc0
T-Type Calcium Channels as Potential Therapeutic Targets in Vemurafenib-Resistant BRAFV600E Melanoma
Autor:
Oscar Maiques, Xavier Dolcet, Izaskun Urdanibia, R.M. Penín, Sandra García-Mulero, Pol Sisó, Nuria Eritja, Carla Barceló, X. Soria, Rosa M. Martí, Isidre Felip, Anna Macià, Josep M. Piulats, Cristina Megino, Raúl Navaridas, Rebeca Sanz-Pamplona, Xavier Matias-Guiu
Publikováno v:
Journal of Investigative Dermatology. 140:1253-1265
Melanoma is a malignant neoplasia that is highly resistant to chemotherapy and radiotherapy and is associated with poor prognosis in advanced stage. Targeting melanoma that harbors the common BRAFV600E mutation with kinase inhibitors, such as vemuraf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b1b83fedd73015ee4538e738f57635a
https://doi.org/10.1016/j.jid.2019.11.014
https://doi.org/10.1016/j.jid.2019.11.014
Author response for 'ARID1A ‐deficient cells require HDAC6 for progression of endometrial carcinoma'
Autor:
null Cristina Megino‐Luque, null Pol Sisó, null Natalia Mota‐Martorell, null Raúl Navaridas, null Inés de la Rosa, null Izaskun Urdanibia, null Manel Albertí‐Valls, null Maria Santacana, null Miquel Pinyol, null Núria Bonifaci, null Anna Macià, null David Llobet‐Navas, null Sònia Gatius, null Xavier Matias‐Guiu, null Núria Eritja
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f30489d8efe854fdcf5243a3ed1c10dd
https://doi.org/10.1002/1878-0261.13193/v2/response1
https://doi.org/10.1002/1878-0261.13193/v2/response1
Autor:
Carlos Lopez-Gil, Carles Domenech, Jose M. Lizcano, Silvia Cabrera, Xavier Matias-Guiu, Cristian Pablo Moiola, Nuria Eritja, Marc Yeste-Velasco, Sonia Solé-Sánchez, Cristina Megino-Luque, Isidre Felip, Pau Muñoz-Guardiola, Ana Oaknin, Antonio Gil-Moreno, Elisabet Megías-Roda, Victor Rodriguez-Freixinos, Xavier Dolcet, Armando Reques, Héctor Pérez-Montoyo, Eva Colas, Jose Alfon, Maria Santacana
Publikováno v:
Gynecologic Oncology. 153:425-435
Objectives The PI3K/AKT/mTOR pathway is frequently overactivated in endometrial cancer (EC). We assessed the efficacy of ABTL0812, a novel first-in-class molecule presenting a unique mechanism of action inhibiting this pathway. Methods We investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c9126111ddd8c8aceb1436ab7ae6c7f
https://doi.org/10.1016/j.ygyno.2019.03.002
https://doi.org/10.1016/j.ygyno.2019.03.002
Autor:
Xavier Dolcet, Gisel Barés, Cristina Megino, Marta Llovera, Natividad Blasco, Ferran Nadeu, Aida Beà, Raúl Navaridas, Daniel Sanchis, Luis Hernández, Elias Campo, Isidre Felip
Publikováno v:
Repositorio Abierto de la UdL
Universitad de Lleida
Cancers
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Volume 13
Issue 15
Cancers, Vol 13, Iss 3803, p 3803 (2021)
Universitad de Lleida
Cancers
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Volume 13
Issue 15
Cancers, Vol 13, Iss 3803, p 3803 (2021)
Simple Summary The PI3K/AKT pathway is involved in cell survival and proliferation. Molecular aberrations and/or hyperactivation of the PI3K-PTEN-AKT axis are frequent in distinct cancer types such as endometrial carcinoma, the most common type of ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc59ab7827a375c87f1fc5d087111619
http://hdl.handle.net/10459.1/71796
http://hdl.handle.net/10459.1/71796