Výsledky vyhledávání - "Cristina, Largo"

CONOCIMIENTO Y SOBRECARGA DEL CUIDADOR PRINCIPAL DE PERSONA MAYOR DEPENDIENTE

Autor: Graciela Olarte Rueda, Yineth Cristina Largo Cardenas, Deisy Lizeth León Acosta, Linda Sarid Del Rosio Sánchez Cubides, Liliana Marcela Ríos Gómez

Publikováno v: Horizonte de enfermeria. 32:256-265

INTRODUCCIÓN: Los cuidadores son los encargados de brindar apoyo a las necesidades básicas de persona mayor. OBJETIVO: Determinar los conocimientos y sobrecarga en el cuidador principal de persona mayor dependiente del municipio de San Gil Santande

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2649a20060d1618d253c499d918e29d1
https://doi.org/10.7764/horiz_enferm.32.3.256-265

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Akademický článek

Multiple myeloma primary cells show a highly rearranged unbalanced genome with amplifications and homozygous deletions irrespective of the presence of immunoglobulin-related chromosome translocations

Autor: Cristina Largo, Borja Saéz, Sara Alvarez, Javier Suela, Bibiana Ferreira, David Blesa, Felipe Prosper, M. Jose Calasanz, Juan C. Cigudosa

Publikováno v: Haematologica, Vol 92, Iss 6 (2007)

Background and Objectives Multiple myeloma (MM) is a malignant plasma cell neoplasia in which genetic studies have shown that genomic changes may affect almost all chromosomes, as shown by fluorescence in situ hybridization (FISH) and comparative gen

Externí odkaz: https://doaj.org/article/fe18bb5eaa0e4371bc2d4dd7aeed1cd0

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The SRY-HMG box gene, SOX4, is a target of gene amplification at chromosome 6p in lung cancer†

Autor: Javier Benitez, Sandra Blanco, Pedro A. Lazo, Jun Yokota, Juan C. Cigudosa, Sara Alvarez, Montse Sanchez-Cespedes, Hans Clevers, Sandra D. Castillo, Marta Sanz-García, Pedro P. Medina, Ana Gonzalez-Neira, Cristina Largo

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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Human Molecular Genetics, 18(7), 1343-1352. Oxford University Press

The search for oncogenes is becoming increasingly important in cancer genetics because they are suitable targets for therapeutic intervention. To identify novel oncogenes, activated by gene amplification, we analyzed cDNA microarrays by high-resoluti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb8f38ad2409f690bec7aab7b1c1d683
https://doi.org/10.1093/hmg/ddp034

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Release of Hypoacetylated and Trimethylated Histone H4 Is an Epigenetic Marker of Early Apoptosis

Autor: Cristina Largo, Juan Casado, Manuel Boix-Chornet, Antonio Núñez, Rosalia Caballero, J. Ignacio Casal, Luis Franco, Mario F. Fraga, Manel Esteller, Jesús Espada, Ana Villar-Garea, Juan C. Cigudosa, Esteban Ballestar

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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Dipòsit Digital de la UB
Universidad de Barcelona

11 p.-5 fig.-1 fig. supl.
Nuclear events such as chromatin condensation, DNA cleavage at internucleosomal sites, and histone release from chromatin are recognized as hallmarks of apoptosis. However, there is no complete understanding of the mole

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f10a5e076dfe85922efaf7a75180e0
https://doi.org/10.1074/jbc.m601136200

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Array CGH and gene-expression profiling reveals distinct genomic instability patterns associated with DNA repair and cell-cycle checkpoint pathways in Ewing's sarcoma

Autor: J C Cigudosa, Nuno Cerveira, Javier Alonso, Francesco Acquadro, Jaime Carrillo, Bibiana I. Ferreira, Cristina Largo, Angel Pestaña, Ana Sastre, Gonzalo Gómez-López, Purificación García-Miguel, A Molares, Javier Suela, Manuel R. Teixeira

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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Ewing's sarcoma (ES) is characterized by specific chromosome translocations, the most common being t(11;22)(q24;q12). Additionally, other type of genetic abnormalities may occur and be relevant for explaining the variable tumour biology and clinical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e526201cc58ea64ddb8dffaa2bf54396
https://pubmed.ncbi.nlm.nih.gov/17952124

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DNA profiling analysis of 100 consecutive de novo acute myeloid leukemia cases reveals patterns of genomic instability that affect all cytogenetic risk groups

Autor: Jose A. Marquez, David Blesa, R García, Javier Suela, Sara Alvarez, J C Cigudosa, María Teresa Ardanaz, Francisco Cifuentes, María D. Odero, Maria-Jose Calasanz, Bibiana I. Ferreira, Cristina Largo

Publikováno v: Leukemia. 21(6)

We have carried out a high-resolution whole genome DNA profiling analysis on 100 bone marrow samples from a consecutive series of de novo acute myeloid leukemia (AML) cases. After discarding copy number changes that are known to be genetic polymorphi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::535add9ef987a771f386a4313701d3fb
https://pubmed.ncbi.nlm.nih.gov/17377590

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Multiple myeloma primary cells show a highly rearranged unbalanced genome with amplifications and homozygous deletions irrespective of the presence of immunoglobulin-related chromosome translocations

Autor: Sara Alvarez, Borja Saez, David Blesa, M. Jose Calasanz, Javier Suela, Bibiana I. Ferreira, Felipe Prosper, Juan C. Cigudosa, Cristina Largo

Publikováno v: Dadun. Depósito Académico Digital de la Universidad de Navarra
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Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8416a700d439cfd31c55f6eb311700f
https://hdl.handle.net/10171/18362

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Simultaneous translocations of FGFR3/MMSET and CCND1 into two different IGH alleles in multiple myeloma: lack of concurrent activation of both proto-oncogenes

Autor: Borja Saez, Idoya Lahortiga, Cristina Largo, José I. Martín-Subero, Felipe Prosper, Juan C. Cigudosa, María D. Odero, María José Calasanz, María José Larrayoz, Reiner Siebert

Publikováno v: Cancer genetics and cytogenetics. 175(1)

The simultaneous occurrence of two different translocations affecting both alleles of the IGH gene has rarely been reported in multiple myeloma. In such a case, two different oncogenes might become transcriptionally deregulated. To investigate this h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e4c51d3be60920969c6199b0d3a1f90
https://pubmed.ncbi.nlm.nih.gov/17498561

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Identification of overexpressed genes in frequently gained/amplified chromosome regions in multiple myeloma

Autor: Cristina, Largo, Sara, Alvarez, Borja, Saez, David, Blesa, Jose I, Martin-Subero, Ines, González-García, Jose A, Brieva, Joaquin, Dopazo, Reiner, Siebert, María J, Calasanz, Juan C, Cigudosa

Publikováno v: Haematologica. 91(2)

Multiple myeloma (MM) is a malignancy characterized by clonal expansion of plasma cells. In 50% of the cases, the neoplastic transformation begins with a chromosomal translocation that juxtaposes the IGH gene locus to an oncogene. Gene copy number ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::965d99f1f40742f3ea834fa22d37185c
https://pubmed.ncbi.nlm.nih.gov/16461292

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