Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Cristina, Geroni"'
Autor:
Alessandro Sammarco, Giorgia Beffagna, Roberta Sacchetto, Andrea Vettori, Federico Bonsembiante, Giulia Scarin, Maria Elena Gelain, Laura Cavicchioli, Silvia Ferro, Cristina Geroni, Paolo Lombardi, Valentina Zappulli
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3317 (2023)
The heterogeneous nature of human breast cancer (HBC) can still lead to therapy inefficacy and high lethality, and new therapeutics as well as new spontaneous animal models are needed to benefit translational HBC research. Dogs are primarily investig
Externí odkaz:
https://doaj.org/article/8f7540fa1e4c43f4a994d739d2f4accc
Autor:
Elisa Pierpaoli, Francesco Piacenza, Gaetano Fiorillo, Paolo Lombardi, Fiorenza Orlando, Carmela Salvatore, Cristina Geroni, Mauro Provinciali
Publikováno v:
Perspective of Recent Advances in Medical Research Vol. 2 ISBN: 9788196055172
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a929efb5a077901e9b3d4a001916ad25
https://doi.org/10.9734/bpi/pramr/v2/3905c
https://doi.org/10.9734/bpi/pramr/v2/3905c
Autor:
Carmela Salvatore, Mauro Provinciali, Gaetano Fiorillo, Paolo Lombardi, Fiorenza Orlando, Cristina Geroni, Elisa Pierpaoli, Francesco Piacenza
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2653, p 2653 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
The natural isoquinoline alkaloid Berberine (BBR) has been shown to possess several therapeutic effects, including anticancer activity. Different BBR derivatives have been designed and synthesized in order to obtain new compounds with enhanced antica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0fff5ff36c69b7c73d49fe5273a58d5
https://www.mdpi.com/1422-0067/22/5/2653
https://www.mdpi.com/1422-0067/22/5/2653
Autor:
Paola Rusmini, Riccardo Cristofani, Barbara Tedesco, Veronica Ferrari, Elio Messi, Margherita Piccolella, Elena Casarotto, Marta Chierichetti, Maria Elena Cicardi, Mariarita Galbiati, Cristina Geroni, Paolo Lombardi, Valeria Crippa, Angelo Poletti
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 3443, p 3443 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 3443, p 3443 (2020)
Background: Accumulation of misfolded proteins is a common hallmark of several neurodegenerative disorders (NDs) which results from a failure or an impairment of the protein quality control (PQC) system. The PQC system is composed by chaperones and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6478e1b049fb3833104b646ac3c0aade
http://europepmc.org/articles/PMC7279252
http://europepmc.org/articles/PMC7279252
Autor:
Cristina Geroni, Veronica Di Paolo, Anastasia De Luca, Chiara Fulci, Manuel Scimeca, Dante Rotili, Anna Maria Caccuri, Luigi Quintieri, Stefano Tomassi, Massimo Serra
Publikováno v:
Biochemical pharmacology. 178
The 7-nitrobenzo[c][1,2,5]oxadiazole (NBD) derivative NBDHEX (compound 1) and its analogue MC3181 (compound 2) have been found to be potent inhibitors of tumor cell growth in vitro and therapeutically active and safe in mice bearing human melanoma xe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36757991baaa1e1825a2b0687b569de0
https://pubmed.ncbi.nlm.nih.gov/32473836
https://pubmed.ncbi.nlm.nih.gov/32473836
Autor:
Francesco Piacenza, Elisa Pierpaoli, Carmela Salvatore, Mauro Provinciali, Paolo Lombardi, Gaetano Fiorillo, Cristina Geroni
Publikováno v:
BioFactors. 44:443-452
Breast cancer (BC) is the most common malignancy and the most common cause of cancer death in elderly women. We recently demonstrated that innovative compounds structurally related to and semisynthetically derived from the plant alkaloid berberine re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b7d5f27387570fc04fd26010ec0471f
https://doi.org/10.1002/biof.1440
https://doi.org/10.1002/biof.1440
Autor:
Elisa, Pierpaoli, Gaetano, Fiorillo, Paolo, Lombardi, Carmela, Salvatore, Cristina, Geroni, Francesco, Piacenza, Mauro, Provinciali
Publikováno v:
BioFactors (Oxford, England). 44(5)
Breast cancer (BC) is the most common malignancy and the most common cause of cancer death in elderly women. We recently demonstrated that innovative compounds structurally related to and semisynthetically derived from the plant alkaloid berberine re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::989c251e05f0e489298f0771a52dfdca
https://pubmed.ncbi.nlm.nih.gov/30178609
https://pubmed.ncbi.nlm.nih.gov/30178609
Autor:
Silvia, Pezzola, Giovanni, Antonini, Cristina, Geroni, Italo, Beria, Maristella, Colombo, Massimo, Broggini, Sergio, Marchini, Nicola, Mongelli, Loris, Leboffe, Robert, MacArthur, Alessia Francesca, Mozzi, Giorgio, Federici, Anna Maria, Caccuri
Publikováno v:
Biochemistry. 49:226-235
Brostallicin is a novel and unique glutathione transferase-activated pro-drug with promising anticancer activity, currently in phase I and II clinical evaluation. In this work, we show that, in comparison with the parental cell line showing low GST l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d551619c23702171c412c9b997d576ee
https://doi.org/10.1021/bi901689s
https://doi.org/10.1021/bi901689s
Autor:
M. Cristina Geroni, Sonnhild Mittag, Karlheinz Friedrich, Paolo Lombardi, Jörg Weiske, Julia Weidemüller, Kai Frederik Albring, Otmar Huber
Publikováno v:
BioFactors. 39:652-662
Aberrant activation of the canonical Wnt/β-catenin signaling pathway has been reported for numerous tumors of different origins. In most cases, mutations in components of the Wnt signaling pathway or in β-catenin itself were detected which ultimate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e595b3e45db92fb07bad32511324b3e8
https://doi.org/10.1002/biof.1133
https://doi.org/10.1002/biof.1133
Autor:
Monica Ganzinelli, Maria Antonietta Sabatino, Massimo Broggini, Cristina Geroni, Roberta Ceruti
Publikováno v:
Scopus-Elsevier
Brostallicin is a DNA minor groove binder that shows enhanced antitumor activity in cells with high glutathione S-transferase (GST)/glutathione content. Prostate cancer cells present, almost invariably, methylation of the GSTP1 gene promoter and, as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::327bde7af83ff75854a59132f861c669
https://doi.org/10.4161/epi.24916
https://doi.org/10.4161/epi.24916