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Autor:
Marta Ibáñez-Navarro, Adrián Fernández, Adela Escudero, Gloria Esteso, Carmen Campos-Silva, Miguel Ángel Navarro-Aguadero, Alejandra Leivas, Beatriz Ruz Caracuel, Carlos Rodríguez-Antolín, Alejandra Ortiz, Alfonso Navarro-Zapata, Carmen Mestre-Durán, Manuel Izquierdo, María Balaguer-Pérez, Cristina Ferreras, Joaquín Martínez-López, Mar Valés-Gómez, Antonio Pérez-Martínez, Lucía Fernández
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionRefractory/relapsed pediatric acute leukemia are still clinically challenging and new therapeutic strategies are needed. Interactions between Natural Killer Group 2D (NKG2D) receptor, expressed in cytotoxic immune cells, and its ligands (
Externí odkaz:
https://doaj.org/article/a050597990ec4b1fb78353f27eb60db9
Autor:
Aitor Gonzaga, Etelvina Andreu, Luis M. Hernández-Blasco, Rut Meseguer, Karima Al-Akioui-Sanz, Bárbara Soria-Juan, Jose Carlos Sanjuan-Gimenez, Cristina Ferreras, Juan R. Tejedo, Guillermo Lopez-Lluch, Rosa Goterris, Loreto Maciá, Jose M. Sempere-Ortells, Abdelkrim Hmadcha, Alberto Borobia, Jose L. Vicario, Ana Bonora, Cristobal Aguilar-Gallardo, Jose L. Poveda, Cristina Arbona, Cristina Alenda, Fabian Tarín, Francisco M. Marco, Esperanza Merino, Francisco Jaime, José Ferreres, Juan Carlos Figueira, Carlos Cañada-Illana, Sergio Querol, Manuel Guerreiro, Cristina Eguizabal, Alejandro Martín-Quirós, Ángel Robles-Marhuenda, Antonio Pérez-Martínez, Carlos Solano, Bernat Soria
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
An unprecedented global social and economic impact as well as a significant number of fatalities have been brought on by the coronavirus disease 2019 (COVID-19), produced by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Acute SARS
Externí odkaz:
https://doaj.org/article/f3f5058998b145e5a81ca6207de2abb5
Autor:
Karima Al-Akioui Sanz, Carlos Echecopar Parente, Cristina Ferreras, Marta Menéndez Ribes, Alfonso Navarro, Carmen Mestre, Laura Clares, José Luis Vicario, Antonio Balas, Raquel De Paz, Eduardo López Granados, Elena Sánchez Zapardiel, Carlos Jiménez, María López-Oliva, Esther Ramos, Francisco Hernández-Oliveros, Antonio Pérez-Martínez
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundImmunocompromised patients are susceptible to high-risk opportunistic infections and malignant diseases. Most antiviral and antifungal drugs are quite toxic, relatively ineffective, and induce resistance in the long term. The transfer of pa
Externí odkaz:
https://doaj.org/article/1686827fd5484660b2e2b5b3552ae8d2
Autor:
Robert D. Morgan, Cristina Ferreras, Isabel Peset, Egle Avizienyte, Andrew G. Renehan, Richard J. Edmondson, Alexander D. Murphy, Shibani Nicum, Thomas Van Brussel, Andrew R. Clamp, Diether Lambrechts, Cong Zhou, Gordon C. Jayson
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-11 (2022)
Highlights Tissue microarrays and germline DNA from women recruited to the phase 3 trial, ICON7, underwent quantitative immunofluorescence for c-MET/VEGFR-2 co-expression and genetic sequencing for single nucleotide polymorphisms (SNPs) VEGF-pathway
Externí odkaz:
https://doaj.org/article/1954157b03284a32b79f59f1c52385eb
Publikováno v:
Revista Portuguesa de Cardiologia, Vol 41, Iss 2, Pp 109-118 (2022)
Introduction: Patent ductus arteriosus (PDA) in preterm infants has been associated with increased mortality and comorbidities. This study aimed to characterize the population of preterm infants diagnosed with PDA and to identify predictive factors o
Externí odkaz:
https://doaj.org/article/90e1c50990e14aee98fcd44269162130
Autor:
Carmen Mestre-Durán, Carla Martín-Cortázar, Blanca García-Solís, Alicia Pernas, Lidia Pertíñez, Víctor Galán, Luisa Sisinni, Laura Clares-Villa, Alfonso Navarro-Zapata, Karima Al-Akioui, Adela Escudero, Cristina Ferreras, Antonio Pérez-Martínez
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
IntroductionNatural killer (NK) cells are lymphocytes from the innate immune system part of the first defense barrier against infected and transformed cells, representing 5%-15% of peripheral blood lymphocytes. The cytotoxic capacity of NK cells is c
Externí odkaz:
https://doaj.org/article/6e841a31af134385b8b7bf77ebe5d148
Autor:
Karima Al-Akioui-Sanz, Bárbara Pascual-Miguel, Mariana Díaz-Almirón, Carmen Mestre-Durán, Alfonso Navarro-Zapata, Laura Clares-Villa, Carla Martín-Cortázar, José Luis Vicario, Miguel Ángel Moreno, Antonio Balas, Raquel De Paz, Jordi Minguillón, Antonio Pérez-Martínez, Cristina Ferreras
Publikováno v:
Cytotherapy. 25:330-340
Autor:
Cristina Ferreras, Lucía Fernández, Laura Clares-Villa, Marta Ibáñez-Navarro, Carla Martín-Cortázar, Isabel Esteban-Rodríguez, Javier Saceda, Antonio Pérez-Martínez
Publikováno v:
Cells, Vol 10, Iss 11, p 2940 (2021)
Central nervous system (CNS) tumours comprise 25% of the paediatric cancer diagnoses and are the leading cause of cancer-related death in children. Current treatments for paediatric CNS tumours are far from optimal and fail for those that relapsed or
Externí odkaz:
https://doaj.org/article/9946090fa33c4c919326a7cf6ec3fe13
Autor:
Álvaro Martínez-Rubio, Salvador Chulián, Cristina Blázquez Goñi, Manuel Ramírez Orellana, Antonio Pérez Martínez, Alfonso Navarro-Zapata, Cristina Ferreras, Victor M. Pérez-García, María Rosa
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12, p 6371 (2021)
Chimeric Antigen Receptor (CAR) T-cell therapy has demonstrated high rates of response in recurrent B-cell Acute Lymphoblastic Leukemia in children and young adults. Despite this success, a fraction of patients’ experience relapse after treatment.
Externí odkaz:
https://doaj.org/article/d5c69ebbce874e56a60e7b255843df4a