Design, synthesis and structure–activity relationship of 2-(3′,4′,5′-trimethoxybenzoyl)-benzo[ b]furan derivatives as a novel class of inhibitors of tubulin polymerization

Autor: Romagnoli, Romeo, Baraldi, Pier Giovanni, Carrion, Maria Dora, Cara, Carlota Lopez, Cruz-Lopez, Olga, Tolomeo, Manlio, Grimaudo, Stefania, Cristina, Antonietta Di, Pipitone, Maria Rosaria, Balzarini, Jan, Zonta, Nicola, Brancale, Andrea, Hamel, Ernest

Publikováno v: In Bioorganic & Medicinal Chemistry 2009 17(19):6862-6871

Synthesis of novel antimitotic agents based on 2-amino-3-aroyl-5-(hetero)arylethynyl thiophene derivatives

Autor: Romagnoli, Romeo, Baraldi, Pier Giovanni, Cruz-Lopez, Olga, Tolomeo, Manlio, Cristina, Antonietta Di, Pipitone, Rosaria Maria, Grimaudo, Stefania, Balzarini, Jan, Brancale, Andrea, Hamel, Ernest

Publikováno v: In Bioorganic & Medicinal Chemistry Letters 2011 21(9):2746-2751

Novel antiproliferative chimeric compounds with marked histone deacetylase inhibitory activity.

Autor: Giacomini E; Department of Pharmacy and Biotechnology, University of Bologna , Via Belmeloro 6, 40126 Bologna, Italy ; Department of Drug Discovery and Development, Italian Institute of Technology , Via Morego 30, 16163 Genova, Italy., Nebbioso A; Department of Biochemistry, Biophysics and General Pathology, Second University of Naples , Vico L. De Crecchio 7, 80138 Naples, Italy., Ciotta A; Department of Biochemistry, Biophysics and General Pathology, Second University of Naples , Vico L. De Crecchio 7, 80138 Naples, Italy., Ianni C; Department of Pharmacy and Biotechnology, University of Bologna , Via Belmeloro 6, 40126 Bologna, Italy., Falchi F; Department of Pharmacy and Biotechnology, University of Bologna , Via Belmeloro 6, 40126 Bologna, Italy ; Department of Drug Discovery and Development, Italian Institute of Technology , Via Morego 30, 16163 Genova, Italy., Roberti M; Department of Pharmacy and Biotechnology, University of Bologna , Via Belmeloro 6, 40126 Bologna, Italy., Tolomeo M; Interdepartmental Center of Research in Clinical Oncology and Department of Infectious Diseases, University of Palermo , Via del Vespro 129, 90127 Palermo, Italy., Grimaudo S; DiBiMIS, Laboratory of Molecular Pathology, Institute of Gastroenterology, University of Palermo , Piazza delle Cliniche 2, 90127 Palermo, Italy., Cristina AD; DiBiMIS, Laboratory of Molecular Pathology, Institute of Gastroenterology, University of Palermo , Piazza delle Cliniche 2, 90127 Palermo, Italy., Pipitone RM; DiBiMIS, Laboratory of Molecular Pathology, Institute of Gastroenterology, University of Palermo , Piazza delle Cliniche 2, 90127 Palermo, Italy., Altucci L; Department of Biochemistry, Biophysics and General Pathology, Second University of Naples , Vico L. De Crecchio 7, 80138 Naples, Italy ; Institute of Genetics and Biophysics, IGB, Via Pietro Castellino 111, 80131 Naples, Italy., Recanatini M; Department of Pharmacy and Biotechnology, University of Bologna , Via Belmeloro 6, 40126 Bologna, Italy.

Publikováno v: ACS medicinal chemistry letters [ACS Med Chem Lett] 2014 Jul 08; Vol. 5 (9), pp. 973-8. Date of Electronic Publication: 2014 Jul 08 (Print Publication: 2014).