Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Cristin M. Bruns"'
Autor:
Rao Zhou, Cristin M. Bruns, Ian M. Bird, Joseph W. Kemnitz, Daniel A. Dumesic, David H. Abbott
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 5, p 2635 (2022)
As in women with polycystic ovary syndrome (PCOS), hyperinsulinemia is associated with anovulation in PCOS-like female rhesus monkeys. Insulin sensitizers ameliorate hyperinsulinemia and stimulate ovulatory menstrual cycles in PCOS-like monkeys. To d
Externí odkaz:
https://doaj.org/article/bd0b3e5c42f94b29b2e99d2799df44d0
Autor:
Cristin M. Bruns, Daniel A. Dumesic, Leah D. Whigham, Scott T Baum, Ricki J. Colman, Michael D. Jensen, Joel R. Eisner, David H. Abbott
Publikováno v:
International Journal of Obesity. 31:1579-1585
Prenatally androgenized (PA) female rhesus monkeys share metabolic abnormalities in common with polycystic ovary syndrome (PCOS) women. Early gestation exposure (E) results in insulin resistance, impaired pancreatic beta-cell function and type 2 diab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd05fcfb14ad42d304398b37e071aa65
https://doi.org/10.1038/sj.ijo.0803638
https://doi.org/10.1038/sj.ijo.0803638
Autor:
Theodore L. Goodfriend, Joseph W. Kemnitz, Cristin M. Bruns, Daniel A. Dumesic, Ian M. Bird, David H. Abbott, Rao Zhou
Publikováno v:
Reproductive Toxicology. 23:438-448
Purpose of the study To determine whether pioglitazone will improve menstrual cyclicity in a fetal programming model for polycystic ovary syndrome. Basic procedures Eight prenatally androgenized (PA) and 5 control female rhesus monkeys of similar age
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ef0f4f3a4ed51a963f62dad73229abb
https://doi.org/10.1016/j.reprotox.2006.12.009
https://doi.org/10.1016/j.reprotox.2006.12.009
Autor:
Joseph W. Kemnitz, Cristin M. Bruns
Publikováno v:
ILAR Journal. 45:160-169
Sex differences and the role of gonadal hormones in modulating insulin sensitivity and glucose tolerance are of increasing interest and importance because of the increasing prevalence of type 2 diabetes mellitus and the metabolic abnormalities associ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52145bb9a325395e2181ee73370e034d
https://doi.org/10.1093/ilar.45.2.160
https://doi.org/10.1093/ilar.45.2.160
Autor:
David H. Abbott, Cristin M. Bruns, Daniel A. Dumesic, Deborah K. Barnett, Jon E. Levine, Rao Zhou, Alice F. Tarantal, Sarah M. Hoffmann
Publikováno v:
Contemporary Endocrinology ISBN: 9781588298317
While the origins of polycystic ovary syndrome (PCOS) in humans are still debated, animal models reliably implicate a fetal origin. Androgen excess, one of the key diagnostic criteria for PCOS and one of its most reliably inherited traits, programs r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e2bed39f0c57b0b869bac9756a0a27a
https://doi.org/10.1007/978-1-59745-108-6_6
https://doi.org/10.1007/978-1-59745-108-6_6
Publikováno v:
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. 13(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0da366af1515dd1d4bca9d8cf4f55db
https://pubmed.ncbi.nlm.nih.gov/17599865
https://pubmed.ncbi.nlm.nih.gov/17599865
Publikováno v:
The Journal of surgical research. 133(2)
Background The historical aspects of the pathophysiology and treatment of Graves’ disease are briefly discussed in this paper. Materials and methods The three treatment modalities of Graves’ disease are anti-thyroid drug therapy, radioactive iodi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::823b8c48e4ad2016bd0f1fdb79b9cc0b
https://pubmed.ncbi.nlm.nih.gov/16458922
https://pubmed.ncbi.nlm.nih.gov/16458922
Publikováno v:
Human reproduction update. 11(4)
The aetiology of polycystic ovary syndrome (PCOS) remains unknown. This familial syndrome is prevalent among reproductive-aged women and its inheritance indicates a dominant regulatory gene with incomplete penetrance. However, promising candidate gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e517a0af14fda9d7fa21f833df89b343
https://pubmed.ncbi.nlm.nih.gov/15941725
https://pubmed.ncbi.nlm.nih.gov/15941725
Autor:
Joel R. Eisner, David H. Abbott, Ricki J. Colman, Scott T Baum, Richard Weindruch, Cristin M. Bruns, Joseph W. Kemnitz
Publikováno v:
The Journal of clinical endocrinology and metabolism. 89(12)
Polycystic ovary syndrome (PCOS) is a familial disease. Affected males harbor some of the metabolic deficits seen in affected females. The prenatally androgenized (PA) female rhesus monkey, an animal model for PCOS, manifests glucoregulatory and repr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db71e90e108d5cc9b52298b393f457e5
https://pubmed.ncbi.nlm.nih.gov/15579780
https://pubmed.ncbi.nlm.nih.gov/15579780