Amitriptyline, clomipramine, and maprotiline attenuate the inflammatory response by inhibiting neutrophil migration and mast cell degranulation

Autor: Cristiano Oliveira Rabelo, Roberto C. P. Lima-Júnior, Ronaldo A. Ribeiro, Breno Bezerra Gomes de Pinho Pessoa, Gerly Anne de Castro Brito, José Alves Gurgel

Publikováno v: Brazilian Journal of Psychiatry, Vol 35, Iss 4, Pp 387-392 (2013)
Brazilian Journal of Psychiatry v.35 n.4 2013
Brazilian Journal of Psychiatry (São Paulo. 1999. Online)
Associação Brasileira de Psiquiatria (ABP)
instacron:ABP
Revista Brasileira de Psiquiatria, Volume: 35, Issue: 4, Pages: 387-392, Published: DEC 2013

Objective: Despite the recognized anti-inflammatory potential of heterocyclic antidepressants, the mechanisms concerning their modulating effects are not completely known. Thus, we evaluated the anti-inflammatory effect of amitriptyline, clomipramine

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