Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Cristiano De Pittà"'
Autor:
Samantha Corrà, Vanessa Checchetto, Michele Brischigliaro, Chiara Rampazzo, Emanuela Bottani, Cristina Gagliani, Katia Cortese, Cristiano De Pittà, Marco Roverso, Diego De Stefani, Sara Bogialli, Massimo Zeviani, Carlo Viscomi, Ildiko Szabò, Rodolfo Costa
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107955- (2023)
Summary: Mutations in MPV17 are a major contributor to mitochondrial DNA (mtDNA) depletion syndromes, a group of inherited genetic conditions due to mtDNA instability. To investigate the role of MPV17 in mtDNA maintenance, we generated and characteri
Externí odkaz:
https://doaj.org/article/ff2c36dac13745499ea74ac5bfd8d600
Autor:
Lorenzo Lupi, Anna Bordin, Gabriele Sales, Davide Colaianni, Adriana Vitiello, Alberto Biscontin, Alberto Reale, Alfredo Garzino-Demo, Angelo Antonini, Giancarlo Ottaviano, Carla Mucignat, Cristina Parolin, Arianna Calistri, Cristiano De Pittà
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe Coronavirus Disease 2019 (COVID-19) is mainly a respiratory syndrome that can affect multiple organ systems, causing a variety of symptoms. Among the most common and characteristic symptoms are deficits in smell and taste perception,
Externí odkaz:
https://doaj.org/article/05402fdb641f4078aafd3dbc9e5655c8
Autor:
Ilenia Urso, Alberto Biscontin, Davide Corso, Cristiano Bertolucci, Chiara Romualdi, Cristiano De Pittà, Bettina Meyer, Gabriele Sales
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract The krill species Euphausia superba plays a critical role in the food chain of the Antarctic ecosystem. Significant changes in climate conditions observed in the Antarctic Peninsula region in the last decades have already altered the distrib
Externí odkaz:
https://doaj.org/article/51eb45e44e244142b98c95556350b15d
Autor:
Svenja J. Müller, Katharina Michael, Ilenia Urso, Gabriele Sales, Cristiano De Pittà, Lavinia Suberg, Wiebke Wessels, Evgeny A. Pakhomov, Bettina Meyer
Publikováno v:
Frontiers in Marine Science, Vol 9 (2022)
The pelagic tunicate Salpa thompsoni is recognized as a major metazoan grazer in the Southern Ocean. Long term observations show an increase in this species’ biomass and a southward shift in its distribution both of which are positively correlated
Externí odkaz:
https://doaj.org/article/f72cc9e8e2a6470fb689da9429668288
Autor:
Roberta Peruzzo, Samantha Corrà, Roberto Costa, Michele Brischigliaro, Tatiana Varanita, Lucia Biasutto, Chiara Rampazzo, Daniele Ghezzi, Luigi Leanza, Mario Zoratti, Massimo Zeviani, Cristiano De Pittà, Carlo Viscomi, Rodolfo Costa, Ildikò Szabò
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Mitochondrial diseases, including those caused by defects in complex III of the respiratory chain, lack curative treatments. Here the authors report that the small molecule pyocyanin has beneficial effects in cells derived from patients with complex
Externí odkaz:
https://doaj.org/article/43a9b3426f6b484aad43fa64d8021ac2
Autor:
Davide Colaianni, Cristiano De Pittà
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
MicroRNAs (miRNAs) are a class of small non-coding RNAs (∼22 nucleotides in length) that negatively regulate protein-coding gene expression post-transcriptionally by targeting mRNAs and triggering either translational repression or RNA degradation.
Externí odkaz:
https://doaj.org/article/1e748677e9cb4033be2bb841399266eb
Autor:
Michele Brischigliaro, Samantha Corrà, Claudia Tregnago, Erika Fernandez-Vizarra, Massimo Zeviani, Rodolfo Costa, Cristiano De Pittà
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Cytochrome c oxidase (COX) deficiency is the biochemical hallmark of several mitochondrial disorders, including subjects affected by mutations in apoptogenic-1 (APOPT1), recently renamed as COA8 (HGNC:20492). Loss-of-function mutations are responsibl
Externí odkaz:
https://doaj.org/article/434ff7e64d5f492bbc89a701f9cfeec9
Autor:
Ada Aita, Caterina Millino, Cosimo Sperti, Beniamina Pacchioni, Mario Plebani, Cristiano De Pittà, Daniela Basso
Publikováno v:
Biomedicines, Vol 9, Iss 7, p 845 (2021)
Background: Tumor stage predicts pancreatic cancer (PDAC) prognosis, but prolonged and short survivals have been described in patients with early-stage tumors. Circulating microRNA (miRNA) are an emerging class of suitable biomarkers for PDAC prognos
Externí odkaz:
https://doaj.org/article/071b40e14c954efda9d920fc16b61469
Autor:
Karla V. Allebrandt, Maris Teder-Laving, Paola Cusumano, Goar Frishman, Rosa Levandovski, Andreas Ruepp, Maria P. L. Hidalgo, Rodolfo Costa, Andres Metspalu, Till Roenneberg, Cristiano De Pittà
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Recognizing that insights into the modulation of sleep duration can emerge by exploring the functional relationships among genes, we used this strategy to explore the genome-wide association results for this trait. We detected two major sign
Externí odkaz:
https://doaj.org/article/63089e19cbdc46febc44f47d63b77f62
Autor:
Paola Cusumano, Alberto Biscontin, Federica Sandrelli, Gabriella M Mazzotta, Claudia Tregnago, Cristiano De Pittà, Rodolfo Costa
Publikováno v:
PLoS Genetics, Vol 14, Iss 7, p e1007500 (2018)
Single microRNAs are usually associated with hundreds of putative target genes that can influence multiple phenotypic traits in Drosophila, ranging from development to behaviour. We investigated the function of Drosophila miR-210 in circadian behavio
Externí odkaz:
https://doaj.org/article/1c1c824ffbbf4fd582fd1dafd0261c3c