Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Cristiano Chiarabelli"'
Autor:
Katarzyna Adamala, Fabrizio Anella, Rafal Wieczorek, Pasquale Stano, Cristiano Chiarabelli, Pier Luigi Luisi
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 9, Iss 14, Pp 1-10 (2014)
In this mini-review we present some experimental approaches to the important issue in the origin of life, namely the origin of nucleic acids and proteins with specific and functional sequences. The formation of macromolecules on prebiotic Earth faces
Externí odkaz:
https://doaj.org/article/28e268e3864544178dbf51b793536bfe
Autor:
Giorgio Mangino, Zulema A Percario, Gianna Fiorucci, Gabriele Vaccari, Filippo Acconcia, Cristiano Chiarabelli, Stefano Leone, Alessia Noto, Florian A Horenkamp, Santiago Manrique, Giovanna Romeo, Fabio Polticelli, Matthias Geyer, Elisabetta Affabris
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e22982 (2011)
BackgroundHIV-1 Nef is a virulence factor that plays multiple roles during HIV replication. Recently, it has been described that Nef intersects the CD40 signalling in macrophages, leading to modification in the pattern of secreted factors that appear
Externí odkaz:
https://doaj.org/article/34fcc4205ca1453aabeae154c7d33f49
Autor:
Monica Borgatti, Eugenia Prus, Ilaria Lampronti, Gabriele Amari, Nicoletta Bianchi, Eitan Fibach, Francesco Chiavilli, Cristina Zuccato, Cristiano Chiarabelli, Roberto Gambari, Maurizio Delcanale
Publikováno v:
European Journal of Pharmacology. 752:84-91
Several investigations have demonstrated a mild clinical status in patients with β-globin disorders and congenital high persistence of foetal haemoglobin. This can be mimicked by a pharmacological increase of foetal γ-globin genes expression and fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7abccb5f3123e60fd7105091fe0fb8dd
https://doi.org/10.1016/j.ejphar.2015.02.018
https://doi.org/10.1016/j.ejphar.2015.02.018
Publikováno v:
Chemistry & Biodiversity. 8:1422-1432
In the last years, we have developed a method for the study of random RNA sequences with the aim of investigating their capacity to assume folded and possibly functionally active (ribozymes) structures. The RNA Foster assay developed in our laborator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72a086651639e529b9d80c018d85efc9
https://doi.org/10.1002/cbdv.201100224
https://doi.org/10.1002/cbdv.201100224
Publikováno v:
Chemical Synthetic Biology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bdee9cd549f5fa7160337a20a69acfb
https://doi.org/10.1002/9780470977873.ch7
https://doi.org/10.1002/9780470977873.ch7
Publikováno v:
Chemical Synthetic Biology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a095222dc453b2d142d04e003bf399d
https://doi.org/10.1002/9780470977873.ch2
https://doi.org/10.1002/9780470977873.ch2
Publikováno v:
Current Opinion in Chemical Biology. 22:v-vii
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f93dc2b49e4205de5b42e1f2ee80b06
https://doi.org/10.1016/j.cbpa.2014.09.036
https://doi.org/10.1016/j.cbpa.2014.09.036
Publikováno v:
Origins of Life and Evolution of Biospheres. 37:379-385
The discovery of catalytic RNA has revolutionised modern molecular biology and bears important implications for the origin of Life research. Catalytic RNA, in particular self-replicating RNA, prompted the hypothesis of an early "RNA world" where RNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::140ff730eca76b4a961db164fdae396a
https://doi.org/10.1007/s11084-007-9098-x
https://doi.org/10.1007/s11084-007-9098-x
Publikováno v:
Chemistry & Biodiversity. 3:860-868
Fold is essential to RNA properties, and, in particular, its thermodynamic stability can be used to monitor RNA-protein or RNA-ligand interactions, and to engineer RNA with novel or improved properties. While clearly valuable, experimental determinat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c97cd9646e3a7e5c4abec160b3ad88e0
https://doi.org/10.1002/cbdv.200690089
https://doi.org/10.1002/cbdv.200690089
Publikováno v:
Chemistry & Biodiversity. 3:869-877
This work lies within the framework of a broader project aimed at exploring the realm of all possible folded polypeptides; the main question addressed here is whether the corresponding RNAs also assume a folded conformation. We present an investigati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c8bbd0867c0f032ef0300b79045a8c8
https://doi.org/10.1002/cbdv.200690090
https://doi.org/10.1002/cbdv.200690090