Synthesis and Antitrypanosomal Activity of 1,4‐Disubstituted Triazole Compounds Based on a 2‐Nitroimidazole Scaffold: a Structure‐Activity Relationship Study

Autor: Gisele Bulhões Portapilla, Sérgio de Albuquerque, Elvis L. F. Assunção, Amarith R. das Neves, Cristiane Y. Kawasoko Shiguemotto, Adriano C. M. Baroni, Diego B. Carvalho

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Chagas disease affects 6-8 million people worldwide, remaining a public health concern. Toxicity, several adverse effects and inefficiency in the chronic stage of the disease are the major challenges regarding the available treatment protocols. This

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feaafaf452dc5dab2f2240d24619e144
https://doi.org/10.1002/cmdc.202000460