Výsledky vyhledávání - "Cristiane M Milanezi"

Akademický článek

Nucleosides present on phlebotomine saliva induce immunossuppression and promote the infection establishment.

Autor: Vanessa Carregaro, José M Ribeiro, Jesus G Valenzuela, Djalma L Souza-Júnior, Diego L Costa, Carlo J F Oliveira, Laís A Sacramento, Manuela S L Nascimento, Cristiane M Milanezi, Fernando Q Cunha, João S Silva

Publikováno v: PLoS Neglected Tropical Diseases, Vol 9, Iss 4, p e0003600 (2015)

Sand fly saliva plays a crucial role in establishing Leishmania infection. We identified adenosine (ADO) and adenosine monophosphate (AMP) as active pharmacologic compounds present in Phlebotomus papatasi saliva that inhibit dendritic cell (DC) funct

Externí odkaz: https://doaj.org/article/a4565c52678c4e9c8704cc5e50e15385

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Akademický článek

In vitro and in vivo trypanocidal activity of H2bdtc-loaded solid lipid nanoparticles.

Autor: Zumira A Carneiro, Pedro I da S Maia, Renata Sesti-Costa, Carla D Lopes, Tatiana A Pereira, Cristiane M Milanezi, Marcelo A Pereira da Silva, Renata F V Lopez, João S Silva, Victor M Deflon

Publikováno v: PLoS Neglected Tropical Diseases, Vol 8, Iss 5, p e2847 (2014)

The parasite Trypanosoma cruzi causes Chagas disease, which remains a serious public health concern and continues to victimize thousands of people, primarily in the poorest regions of Latin America. In the search for new therapeutic drugs against T.

Externí odkaz: https://doaj.org/article/93a1ffc9bb3649a489eb58a4884a5698

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Akademický článek

Toxoplasma gondii soluble tachyzoite antigen triggers protective mechanisms against fatal intestinal pathology in oral infection of C57BL/6 mice.

Autor: Luciana Benevides, Cristina R Cardoso, Cristiane M Milanezi, Letícia S Castro-Filice, Paulo V C Barenco, Romulo O Sousa, Rosangela M Rodrigues, José R Mineo, João S Silva, Neide M Silva

Publikováno v: PLoS ONE, Vol 8, Iss 9, p e75138 (2013)

Toxoplasma gondii induces a potent IL-12 response early in infection that results in IFN-γ-dependent control of parasite growth. It was previously shown that T. gondii soluble tachyzoite antigen (STAg) injected 48 hr before intraperitoneal infection

Externí odkaz: https://doaj.org/article/5524d59ec06445198bbf066baefed8e2

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Akademický článek

Cell-free antigens from Paracoccidioides brasiliensis drive IL-4 production and increase the severity of paracoccidioidomycosis.

Autor: Karen A Cavassani, Fabrine S M Tristao, Leandro L Oliveira, Fernanda A Rocha, Jaqueline O Vancim, Ana Paula Moreira, Ana Paula Campanelli, Luciano A Panagio, Cristiane M Milanezi, Roberto Martinez, Marcos A Rossi, Joao S Silva

Publikováno v: PLoS ONE, Vol 6, Iss 6, p e21423 (2011)

The thermally dimorphic fungus Paracoccidioides brasiliensis (Pb) is the causative agent of paracoccidioidomycosis (PCM), one of the most frequent systemic mycosis that affects the rural population in Latin America. PCM is characterized by a chronic

Externí odkaz: https://doaj.org/article/a586a14b259e42119ba7fa8f9f81aa11

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Akademický článek

BALB/c mice infected with antimony treatment refractory isolate of Leishmania braziliensis present severe lesions due to IL-4 production.

Autor: Diego L Costa, Vanessa Carregaro, Djalma S Lima-Júnior, Neide M Silva, Cristiane M Milanezi, Cristina R Cardoso, Ângela Giudice, Amélia R de Jesus, Edgar M Carvalho, Roque P Almeida, João S Silva

Publikováno v: PLoS Neglected Tropical Diseases, Vol 5, Iss 3, p e965 (2011)

BACKGROUND: Leishmania braziliensis is the main causative agent of cutaneous leishmaniasis in Brazil. Protection against infection is related to development of Th1 responses, but the mechanisms that mediate susceptibility are still poorly understood.

Externí odkaz: https://doaj.org/article/3965a60f362b4354946e8ce974cefe65

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Akademický článek

IL-17 produced during Trypanosoma cruzi infection plays a central role in regulating parasite-induced myocarditis.

Autor: Paulo Marcos da Matta Guedes, Fredy R S Gutierrez, Flavia L Maia, Cristiane M Milanezi, Grace K Silva, Wander R Pavanelli, João S Silva

Publikováno v: PLoS Neglected Tropical Diseases, Vol 4, Iss 2, p e604 (2010)

BACKGROUND: Chagas disease is a neglected disease caused by the intracellular parasite Trypanosoma cruzi. Around 30% of the infected patients develop chronic cardiomyopathy or megasyndromes, which are high-cost morbid conditions. Immune response agai

Externí odkaz: https://doaj.org/article/643f68d6e5384304936ee1f875283eb0

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Akademický článek

The IgG glycome of SARS-CoV-2 infected individuals reflects disease course and severity

Autor: Sterre L. Siekman, Tamas Pongracz, Wenjun Wang, Jan Nouta, Peter G. Kremsner, Pedro Vieira da Silva-Neto, Meral Esen, Andrea Kreidenweiss, Jana Held, Átila Alexandre Trapé, Rolf Fendel, Isabel Kinney Ferreira de Miranda Santos, Manfred Wuhrer, ImmunoCovid Consortium, Alessandro P. de Amorim, Jamille G M. Argolo, Rita de C.C. Barbieri, Marcelo Dias-Baruffi, Victor A F. Bastos, Vânia L D. Bonat, Cristina Ribeiro de Barros Cardoso, Ingryd Carmona-Garcia, Jonatan C S de Carvalho, Leticia F. Constant, Augusto M. Degiovani, Cassia F.S.L. Dias, Lúcia H. Faccioli, Marley R. Feitosa, Omar Feres, Ana Paula Morais Fernandes, Talita M. Fernandes, Thais F C. Fraga-Silva, Carlos Fuzo, Isabelle C. Guarneri, Cristiane M. Milanezi, Caroline T. Garbato, Gilberto Gambero Gaspar, Ângelo A.F. Júnior, Sandra R. Maruyama, Debora C. Nepomuceno, Nicola T. Neto, Camilla Narjara Simão Oliveira, Fátima M. Ostini, Rogerio S. Parra, Malena M. Pérez, Vinı́cius E. Pimentel, Giovanna da S. Porcel, José J R da Rocha, Lilian C. Rodrigues, Elisa M S. Russo, Dayane P. da Silva, Rafael C. da Silva, Carlos Arterio Sorgi, Camila O S. Souza, Diana M. Toro, Angelina L. Viana, Fernando Crivelenti Vilar, Ana C. Xavier, Kamila Zaparoli

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

Immunoglobulin G (IgG) antibodies play an important role in the immune response against viruses such as SARS-CoV-2. As the effector functions of IgG are modulated by N-glycosylation of the Fc region, the structure and possible function of the IgG N-g

Externí odkaz: https://doaj.org/article/6158a9fbd2d94ee5a9418faadd9e7247

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Akademický článek

NLRC4 inhibits NLRP3 inflammasome and abrogates effective antifungal CD8+ T cell responses

Autor: Camila O.S. Souza, Natália Ketelut-Carneiro, Cristiane M. Milanezi, Lúcia H. Faccioli, Luiz G. Gardinassi, João S. Silva

Publikováno v: iScience, Vol 24, Iss 6, Pp 102548- (2021)

Summary: The recognition of fungi by intracellular NOD-like receptors (NLRs) induces inflammasome assembly and activation. Although the NLRC4 inflammasome has been extensively studied in bacterial infections, its role during fungal infections is uncl

Externí odkaz: https://doaj.org/article/8c953e87d780462f8f6d2c8bb1180761

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