Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Cristiana O'Brien"'
Autor:
Christopher Gibson, Shirley C. Wang, Arcturus Phoon, Nayana Thalanki Anantha, Kathryn Ottolino-Perry, Stephen Petropoulos, Zuha Qureshi, Vasanth Subramanian, Anam Shahid, Cristiana O’Brien, Steven Carcone, Suzanne Chung, Teresa Tsui, Viktor Son, Mayleen Sukhram, Fannong Meng, Susan J. Done, Alexandra M. Easson, Tulin Cil, Michael Reedijk, Wey L. Leong, Ralph S. DaCosta
Publikováno v:
BMC Biomedical Engineering, Vol 6, Iss 1, Pp 1-20 (2024)
Abstract Background Visualization of cancer during breast conserving surgery (BCS) remains challenging; the BCS reoperation rate is reported to be 20-70% of patients. An urgent clinical need exists for real-time intraoperative visualization of breast
Externí odkaz:
https://doaj.org/article/bcd3fc8fc51b4245b07597090995945f
Autor:
Cristiana O’Brien, Tianyi Ling, Jacob M. Berman, Rachel Culp-Hill, Julie A. Reisz, Vincent Rondeau, Soheil Jahangiri, Jonathan St-Germain, Vinitha Macwan, Audrey Astori, Andy Zeng, Jun Young Hong, Meng Li, Min Yang, Sadhan Jana, Fabia Gamboni, Emily Tsao, Weiyi Liu, John E. Dick, Hening Lin, Ari Melnick, Anastasia Tikhonova, Andrea Arruda, Mark D. Minden, Brian Raught, Angelo D'Alessandro, Courtney L. Jones
Publikováno v:
Haematologica, Vol 108, Iss 9 (2023)
Outcomes for patients with acute myeloid leukemia (AML) remain poor due to the inability of current therapeutic regimens to fully eradicate disease-initiating leukemia stem cells (LSC). Previous studies have demonstrated that oxidative phosphorylatio
Externí odkaz:
https://doaj.org/article/365041b041f04292a5cd13ba5d068c3d
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100248- (2021)
Summary: Isolation of leukemia stem cells presents a challenge due to the heterogeneity of the immunophenotypic markers commonly used to identify blood stem cells. Several studies have reported that relative levels of reactive oxygen species (ROS) ca
Externí odkaz:
https://doaj.org/article/b21bac2c3bff4bec873a355d6d5a660b
Autor:
Cristiana O'Brien, Tianyi Ling, Jacob Berman, Rachel Culp-Hill, Julie A. Reisz, Vincent Rondeau, Soheil Jahangiri, Jonathan St-Germain, Vinitha Macwan, Audrey Astori, Andy G.X. Zeng, Jun Young Hong, Meng Li, Min Yang, Sadhan Jana, John E. Dick, Hening Lin, Ari Melnick, Anastasia N Tikhonova, Andrea Arruda, Mark D. Minden, Brian Raught, Angelo D'Alessandro, Courtney L Jones
Publikováno v:
Blood. 140:104-106
Autor:
Geethu Emily Thomas, Grace Egan, Laura García-Prat, Aaron Botham, Veronique Voisin, Parasvi S. Patel, Fieke W. Hoff, Jordan Chin, Boaz Nachmias, Kerstin B. Kaufmann, Dilshad H. Khan, Rose Hurren, Xiaoming Wang, Marcela Gronda, Neil MacLean, Cristiana O’Brien, Rashim P. Singh, Courtney L. Jones, Shane M. Harding, Brian Raught, Andrea Arruda, Mark D. Minden, Gary D. Bader, Razq Hakem, Steve Kornblau, John E. Dick, Aaron D. Schimmer
Publikováno v:
Nature Cell Biology, 24(6), 872-884. Nature Publishing Group
Thomas, Egan et al. report that hexokinase 2 localizes to the nucleus of leukaemic and normal haematopoietic cells to maintain stemness by interacting with nuclear proteins and modulating chromatin accessibility independently of its kinase activity.M
Autor:
Vincent Rondeau, Cristiana O’Brien, Jacob M Berman, Duhan Yendi, Tianyi Ling, Aleksandra Bourdine, Aarushi Gupta, Jonathan St-Germain, Rachel Culp-Hill, Julie A Reisz, Soheil Jahangiri-Tazehkand, Anastasia Tikhonova, Andrea Arruda, Mark D Minden, Angelo D’Alessandro, Brian Raught, Courtney L Jones
Publikováno v:
Blood Cancer Discovery. 4:A54-A54
Outcomes for patients with acute myeloid leukemia (AML) remain poor due to the inability of current therapies to fully eradicate disease initiating leukemia stem cells (LSCs) (Shlush et al., 2017). Many studies have demonstrated that LSCs have unique
Autor:
Vincent Rondeau, Rachel Culp-Hill, Cristiana O’Brien, Jacob Berman, Julie A. Reisz, Duhan Yendi, Tianyi Ling, Soheil Janangiri, Anastasia Tikhonova, Angelo D’Alessandro, Courtney Jones
Publikováno v:
Cancer Research. 83:NG07-NG07
Acute myeloid leukemia (AML) is a devastating hematologic malignancy diagnosed in over 20,000 patients each year in the United States. The five-year survival rate in adult AML is less than 30%, highlighting the need for novel therapies to treat this
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100248-(2021)
STAR Protocols
STAR Protocols
Summary Isolation of leukemia stem cells presents a challenge due to the heterogeneity of the immunophenotypic markers commonly used to identify blood stem cells. Several studies have reported that relative levels of reactive oxygen species (ROS) can
Autor:
Courtney L. Jones, Angelo D'Alessandro, Min Yang, Jacob Berman, Vincent Rondeau, Cristiana O'Brien, Hening Lin, Ari Melnick, Jun Young Hong, Rachel Culp-Hill, Tianyi Ling, Meng Li, Mark D. Minden, Julie A. Reisz, Andrea Arruda
Publikováno v:
Blood. 138:2240-2240
Acute myeloid leukemia (AML) in adults has a 5-year survival of approximately 30% and a high rate of disease recurrence in part due to our inability to eliminate the disease-initiating leukemic stem cells (LSCs) (Shlush et al. Nature, 2017). Previous