Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Cristian Ruiz-Moreno"'
Autor:
Peter Brazda, Cristian Ruiz-Moreno, Wout L. Megchelenbrink, Henri J. L. M. Timmers, Hendrik G. Stunnenberg
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Pheochromocytomas (PC) and paragangliomas (PG) are rare neuroendocrine tumors with varied genetic makeup and are associated with high cardiovascular morbidity and a variable risk of malignancy. The source of the transcriptional heterogeneity of the d
Externí odkaz:
https://doaj.org/article/8b4e2d0db1f646909769e70a7e9c8113
Autor:
Farid Keramati, Guus P. Leijte, Niklas Bruse, Inge Grondman, Ehsan Habibi, Cristian Ruiz-Moreno, Wout Megchelenbrink, Annemieke M. Peters van Ton, Hidde Heesakkers, Manita Bremmers, Erinke van Grinsven, Kiki Tesselaar, Selma van Staveren, Walter van der Velden, Frank Preijers, Jelle Gerretsen, Mihai G. Netea, Hendrik G. Stunnenberg, Peter Pickkers, Matthijs Kox
Systemic inflammation (SI) plays a detrimental role in various conditions with high mortality rates1–4. SI manifests an acute hyperinflammation followed by long-lasting immunosuppression, increasing patients’ risks for secondary infections and im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9df4312ac238c3009c9c91dd445f8bf5
https://doi.org/10.1101/2022.10.06.22280312
https://doi.org/10.1101/2022.10.06.22280312
Autor:
Cristian Ruiz-Moreno, Sergio Marco Salas, Erik Samuelsson, Sebastian Brandner, Mariette E.G. Kranendonk, Mats Nilsson, Hendrik G. Stunnenberg
SUMMARYGlioblastoma, isocitrate dehydrogenase (IDH)-wildtype (hereafter, GB), is an aggressive brain malignancy associated with a dismal prognosis and poor quality of life. Single-cell RNA sequencing has helped to grasp the complexity of the cell sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22a9315adc3ba7f0ea411e40995b8f32
https://doi.org/10.1101/2022.08.27.505439
https://doi.org/10.1101/2022.08.27.505439
Autor:
Jaime Gállego Pérez-Larraya, Marc Garcia-Moure, Sara Labiano, Ana Patiño-García, Jessica Dobbs, Marisol Gonzalez-Huarriz, Marta Zalacain, Lucia Marrodan, Naiara Martinez-Velez, Montserrat Puigdelloses, Virginia Laspidea, Itziar Astigarraga, Blanca Lopez-Ibor, Ofelia Cruz, Miren Oscoz Lizarbe, Sandra Hervas-Stubbs, Gorka Alkorta-Aranburu, Ibon Tamayo, Beatriz Tavira, Ruben Hernandez-Alcoceba, Chris Jones, Gitanjali Dharmadhikari, Cristian Ruiz-Moreno, Henk Stunnenberg, Esther Hulleman, Jasper van der Lugt, Miguel Á. Idoate, Ricardo Diez-Valle, Inés Esparragosa Vázquez, Maria Villalba, Carlos de Andrea, Jorge M. Núñez-Córdoba, Brett Ewald, Joan Robbins, Juan Fueyo, Candelaria Gomez-Manzano, Frederick F. Lang, Sonia Tejada, Marta M. Alonso
Publikováno v:
NEW ENGLAND JOURNAL OF MEDICINE
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
Gállego Pérez-Larraya, J, Garcia-Moure, M, Labiano, S, Patiño-García, A, Dobbs, J, Gonzalez-Huarriz, M, Zalacain, M, Marrodan, L, Martinez-Velez, N, Puigdelloses, M, Laspidea, V, Astigarraga, I, Lopez-Ibor, B, Cruz, O, Oscoz Lizarbe, M, Hervas-Stubbs, S, Alkorta-Aranburu, G, Tamayo, I, Tavira, B, Hernandez-Alcoceba, R, Jones, C, Dharmadhikari, G, Ruiz-Moreno, C, Stunnenberg, H, Hulleman, E, van der Lugt, J, Idoate, M Á, Diez-Valle, R, Esparragosa Vázquez, I, Villalba, M, de Andrea, C, Núñez-Córdoba, J M, Ewald, B, Robbins, J, Fueyo, J, Gomez-Manzano, C, Lang, F F, Tejada, S & Alonso, M M 2022, ' Oncolytic DNX-2401 Virus for Pediatric Diffuse Intrinsic Pontine Glioma ', The New England journal of medicine, vol. 386, no. 26, pp. 2471-2481 . https://doi.org/10.1056/NEJMoa2202028
The New England journal of medicine, 386(26), 2471-2481. Massachussetts Medical Society
New England Journal of Medicine
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
Gállego Pérez-Larraya, J, Garcia-Moure, M, Labiano, S, Patiño-García, A, Dobbs, J, Gonzalez-Huarriz, M, Zalacain, M, Marrodan, L, Martinez-Velez, N, Puigdelloses, M, Laspidea, V, Astigarraga, I, Lopez-Ibor, B, Cruz, O, Oscoz Lizarbe, M, Hervas-Stubbs, S, Alkorta-Aranburu, G, Tamayo, I, Tavira, B, Hernandez-Alcoceba, R, Jones, C, Dharmadhikari, G, Ruiz-Moreno, C, Stunnenberg, H, Hulleman, E, van der Lugt, J, Idoate, M Á, Diez-Valle, R, Esparragosa Vázquez, I, Villalba, M, de Andrea, C, Núñez-Córdoba, J M, Ewald, B, Robbins, J, Fueyo, J, Gomez-Manzano, C, Lang, F F, Tejada, S & Alonso, M M 2022, ' Oncolytic DNX-2401 Virus for Pediatric Diffuse Intrinsic Pontine Glioma ', The New England journal of medicine, vol. 386, no. 26, pp. 2471-2481 . https://doi.org/10.1056/NEJMoa2202028
The New England journal of medicine, 386(26), 2471-2481. Massachussetts Medical Society
New England Journal of Medicine
BACKGROUND: Pediatric patients with diffuse intrinsic pontine glioma (DIPG) have a poor prognosis, with a median survival of less than 1 year. Oncolytic viral therapy has been evaluated in patients with pediatric gliomas elsewhere in the brain, but d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52534586ace52296f64ef745d8c7c56e
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=21821
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=21821
Autor:
Cristian Ruiz-Moreno, Sergio Marco Salas, Erik Samuelsson, Sebastian Brandner, Mariette Kranendonk, Mats Nilsson, Hendrik Stunnenberg
Publikováno v:
Neuro-Oncology. 24:vii287-vii287
Glioblastoma (GBM) is the most aggressive and deadliest brain tumor in adults. Single-cell RNA sequencing (scRNA-seq) has helped to grasp the complexity of the cell states and dynamic changes within the tumor microenvironment (TME). To better capture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1dcb172171791d38669d6786d9835a2a
https://doi.org/10.1093/neuonc/noac209.1113
https://doi.org/10.1093/neuonc/noac209.1113
Autor:
Dannis G. van Vuurden, Lennart Kester, Cristian Ruiz-Moreno, Peter Brazda, Mariette E.G. Kranendonk, Wout Megchelenbrink, Brigit te Pas, Hendrik G. Stunnenberg, Kim Boshuisen, Jasper Van der Lugt, Farid Keramati, Helena C. Besse
Macrophage (Mϕ) repolarization from a pro-tumor, immunosuppressive phenotype towards an anti-tumor, pro-inflammatory state represents a promising therapeutic strategy in patients with cancer1. Successful reprogramming of Mϕ in a clinical setting ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4eb003480da8175c228d3228c5e3ed16
https://doi.org/10.1101/2021.07.19.21259735
https://doi.org/10.1101/2021.07.19.21259735
Autor:
Cristian Ruiz-Moreno, Anne Eugster, Martina Beretta, Franziska Roestel, Elisa Jentho, Michael Bauer, Tatyana Grinenko, Hendrik G. Stunnenberg, Mihai G. Netea, Lydia Kalafati, Boris Novakovic, Ioannis Kourtzelis, Wout Megchelenbrink, Triantafyllos Chavakis, Peter Bohm, Rui Martins, Sebastian Weis, Leo A. B. Joosten, Maren Godmann, Joel Guerra, Miguel P. Soares
Publikováno v:
Proceedings of the National Academy of Sciences USA, 118
Trained innate immunity, long-lasting epigenetic modulation, and skewed myelopoiesis by heme
Proceedings of the National Academy of Sciences USA, 118, 42
Proceedings of the National Academy of Sciences of the United States of America
Trained innate immunity, long-lasting epigenetic modulation, and skewed myelopoiesis by heme
Proceedings of the National Academy of Sciences USA, 118, 42
Proceedings of the National Academy of Sciences of the United States of America
Significance During infection, extracellular “labile” heme, released from damaged red blood or parenchymal cells, acts as prototypical alarmin stimulating myeloid cells. A characteristic hallmark of myeloid cell activation is the development of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::802e6edb735c52a46acd58d3c5652396
https://doi.org/10.1073/pnas.2102698118
https://doi.org/10.1073/pnas.2102698118
Autor:
Anne Eugster, Peter Bohm, Rui Martins, Joel Guerra, Franziska Roestel, Elisa Jentho, Triantafyllos Chavakis, Lydia Kalafati, Miguel Perreira Soares, Tatyana Grinenko, Leo A. B. Joosten, Maren Godmann, Hendrik G. Stunnenberg, Boris Novakovic, Martina Beretta, Michael Bauer, Sebastian Weis, Cristian Ruiz-Moreno, Ioannis Kourtzelis, Mihai G. Netea
Trained immunity defines long-lasting adaptive responses of innate immunity, mediated by transcriptional and epigenetic modifications of myeloid cells. Here, we report that labile heme, an alarmin released extracellularily upon tissue damage and hemo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ddd92736513bcb0188908c6997f6bcf
Publikováno v:
Toxicology in Vitro. 50:336-346
Acute lymphoblastic leukemia (ALL) is still an incurable hematologic malignant disorder. Therefore, novel therapeutic approaches are urgently required. In this study, we tested the pro-apoptotic properties of minocycline (Mino) in human peripheral bl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af71959fbe5ee04e30583145d3c8b38c
https://doi.org/10.1016/j.tiv.2018.03.012
https://doi.org/10.1016/j.tiv.2018.03.012
Autor:
Cristian Ruiz-Moreno, Carlos Velez-Pardo, Betty Lopez-Osorio, Marlene Jimenez-Del-Rio, Ligia Sierra-Garcia
Publikováno v:
Apoptosis. 21:1019-1032
D-α-tocopheryl polyethylene glycol 1000 succinate (TPGS) is a water-soluble derivative of natural vitamin E commonly used as a drug delivery agent. Recently, TPGS alone has been reported to induce cell death in lung, breast and prostate cancer. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c0a3f459c8e1762cdd0039338e6af39
https://doi.org/10.1007/s10495-016-1266-x
https://doi.org/10.1007/s10495-016-1266-x