Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Cristian Prieto"'
Autor:
Chun Kew, Cristian Prieto-Garcia, Anshu Bhattacharya, Manuela Tietgen, Craig R. MacNair, Lindsey A. Carfrae, João Mello-Vieira, Stephan Klatt, Yi-Lin Cheng, Rajeshwari Rathore, Elise Gradhand, Ingrid Fleming, Man-Wah Tan, Stephan Göttig, Volkhard A. J. Kempf, Ivan Dikic
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Acinetobacter baumannii is a pathogenic and multidrug-resistant Gram-negative bacterium that causes severe nosocomial infections. To better understand the mechanism of pathogenesis, we compare the proteomes of uninfected and infected human c
Externí odkaz:
https://doaj.org/article/cc857566b9914285a523bd2ab2b86cfe
Autor:
Cristian Prieto‐Garcia, Oliver Hartmann, Michaela Reissland, Fabian Braun, Süleyman Bozkurt, Nikolett Pahor, Carmina Fuss, Andreas Schirbel, Christina Schülein‐Völk, Alexander Buchberger, Marco A. Calzado Canale, Mathias Rosenfeldt, Ivan Dikic, Christian Münch, Markus E. Diefenbacher
Publikováno v:
Molecular Oncology, Vol 16, Iss 17, Pp 3082-3106 (2022)
Oncogenic transformation of lung epithelial cells is a multistep process, frequently starting with the inactivation of tumour suppressors and subsequent development of activating mutations in proto‐oncogenes, such as members of the PI3K or MAPK fam
Externí odkaz:
https://doaj.org/article/dce85c56cd0547f996b0cfb97c5fb3dc
Autor:
Thomas Fischer, Oliver Hartmann, Michaela Reissland, Cristian Prieto-Garcia, Kevin Klann, Nikolett Pahor, Christina Schülein-Völk, Apoorva Baluapuri, Bülent Polat, Arya Abazari, Elena Gerhard-Hartmann, Hans-Georg Kopp, Frank Essmann, Mathias Rosenfeldt, Christian Münch, Michael Flentje, Markus E. Diefenbacher
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-22 (2022)
Abstract Background Despite advances in treatment of patients with non-small cell lung cancer, carriers of certain genetic alterations are prone to failure. One such factor frequently mutated, is the tumor suppressor PTEN. These tumors are supposed t
Externí odkaz:
https://doaj.org/article/6e2b77747e884b2d9b01fa05018ce46e
Autor:
Cristian Prieto‐Garcia, Oliver Hartmann, Michaela Reissland, Fabian Braun, Thomas Fischer, Susanne Walz, Christina Schülein‐Völk, Ursula Eilers, Carsten P Ade, Marco A Calzado, Amir Orian, Hans M Maric, Christian Münch, Mathias Rosenfeldt, Martin Eilers, Markus E Diefenbacher
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 4, Pp 1-25 (2020)
Abstract The transcription factor ∆Np63 is a master regulator of epithelial cell identity and essential for the survival of squamous cell carcinoma (SCC) of lung, head and neck, oesophagus, cervix and skin. Here, we report that the deubiquitylase U
Externí odkaz:
https://doaj.org/article/1898fb6a9b9447fe970065bbeeb04bce
Autor:
Oliver Hartmann, Michaela Reissland, Carina R. Maier, Thomas Fischer, Cristian Prieto-Garcia, Apoorva Baluapuri, Jessica Schwarz, Werner Schmitz, Martin Garrido-Rodriguez, Nikolett Pahor, Clare C. Davies, Florian Bassermann, Amir Orian, Elmar Wolf, Almut Schulze, Marco A. Calzado, Mathias T. Rosenfeldt, Markus E. Diefenbacher
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Lung cancer is the most common cancer worldwide and the leading cause of cancer-related deaths in both men and women. Despite the development of novel therapeutic interventions, the 5-year survival rate for non-small cell lung cancer (NSCLC) patients
Externí odkaz:
https://doaj.org/article/25bb6c9a9e3b4539a37791d85b52657e
Autor:
Sergio Hernández, Francisca Álvarez-Astudillo, Daniel Garrido, Cristian Prieto, Alejandra Loyola, Rodrigo A. Villanueva
Publikováno v:
Biomedicines, Vol 9, Iss 11, p 1701 (2021)
Hepatitis B virus (HBV) X protein (HBx) is a viral regulatory and multifunctional protein. It is well-known that the canonical HBx reading frame bears two phylogenetically conserved internal in-frame translational initiation codons at Met2 and Met3,
Externí odkaz:
https://doaj.org/article/2ff36feca30d4ce6a58f81509da60022
Autor:
Cristian Prieto-Garcia, Ines Tomašković, Varun Jayeshkumar Shah, Ivan Dikic, Markus Diefenbacher
Publikováno v:
Cells, Vol 10, Iss 10, p 2652 (2021)
Squamous cell carcinomas are therapeutically challenging tumor entities. Low response rates to radiotherapy and chemotherapy are commonly observed in squamous patients and, accordingly, the mortality rate is relatively high compared to other tumor en
Externí odkaz:
https://doaj.org/article/0a3518fbff3945b8ac7cb8a5fae2f7e3
Autor:
Carina R. Maier, Oliver Hartmann, Cristian Prieto-Garcia, Kamal M. Al-Shami, Lisa Schlicker, Felix C. E. Vogel, Silke Haid, Kevin Klann, Viktoria Buck, Christian Münch, Werner Schmitz, Elias Einig, Bastian Krenz, Marco A. Calzado, Martin Eilers, Nikita Popov, Mathias T. Rosenfeldt, Markus E. Diefenbacher, Almut Schulze
Publikováno v:
Cell Death & Differentiation.
SREBP2 is a master regulator of the mevalonate pathway (MVP), a biosynthetic process that drives the synthesis of dolichol, heme A, ubiquinone and cholesterol and also provides substrates for protein prenylation. Here, we identify SREBP2 as a novel s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::daa7350dfb4e409ead8c22bfc7313fb8
https://doi.org/10.1038/s41418-023-01173-6
https://doi.org/10.1038/s41418-023-01173-6
Autor:
Michaela Reissland, Oliver Hartmann, Saskia Tauch, Cristian Prieto-Garcia, Clemens Schulte, Daniel Solvie, Sinah Loebbert, Anne-Claire Jacomin, Marina Pesic, Jeroen Bugter, Christina Schülein-Völk, Carmina Fuss, Nikolett Pahor, Carsten Ade, Viktoria Buck, Michael Potente, Vivian Li, Gerti Beliu, Armin Wiegering, Eliya Bitman-Lotan, Tom Grossmann, Mathias Rosenfeldt, Martin Eilers, Hans Maric, Madelon Maurice, Florian Greten, Ivan Dikic, Amir Oryan, Peter Gallant, Markus Diefenbacher
The contribution of deubiquitylating enzymes to β-Catenin stabilisation in intestinal stem cells and colorectal cancer (CRC) is poorly understood. Here, we report the deubiquitylase USP10 as an APC-truncation- specific enhancer of β-Catenin stabili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cbc08d25e5786a9e89293d3727f74c9
https://doi.org/10.21203/rs.3.rs-2647009/v1
https://doi.org/10.21203/rs.3.rs-2647009/v1
Autor:
Cristian Prieto, Juan Montecinos, Gustavo Jiménez, Constanza Riquelme, Daniel Garrido, Sergio Hernández, Alejandra Loyola, Rodrigo A. Villanueva
Publikováno v:
Molecules, Vol 26, Iss 5, p 1254 (2021)
Hepatitis B virus (HBV) is a circular, and partially double-stranded DNA virus. Upon infection, the viral genome is translocated into the cell nucleus, generating the covalently closed circular DNA (cccDNA) intermediate, and forming a mini chromosome
Externí odkaz:
https://doaj.org/article/2ffd390303574341a4386e573b5dab19