Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Cristian NEACSU"'
Autor:
Sarah Thull, Cristian Neacsu, Andrias O. O'Reilly, Stefanie Bothe, Ralf Hausmann, Tobias Huth, Jannis Meents, Angelika Lampert
Publikováno v:
Data in Brief, Vol 31, Iss , Pp 105844- (2020)
This article describes the effect of the pyrethroid insecticide deltamethrin on the cardiac voltage-gated sodium channel Nav1.5. Two concentrations of deltamethrin were used and the effects were compared with those of the sea anemone toxin ATx-II and
Externí odkaz:
https://doaj.org/article/d30ee82ed72c46a08ad9495034c40169
Publikováno v:
Cephalalgia Reports, Vol 2 (2019)
Background: Migraine therapy with sumatriptan may cause adverse side effects like pain at the injection site, muscle pain, and transient aggravation of headaches. In animal experiments, sumatriptan excited or sensitized slowly conducting meningeal af
Externí odkaz:
https://doaj.org/article/ca690af119f643229f1e8f84d545a4e3
Autor:
Esther Eberhardt, Steven Havlicek, Diana Schmidt, Andrea S. Link, Cristian Neacsu, Zacharias Kohl, Martin Hampl, Andreas M. Kist, Alexandra Klinger, Carla Nau, Jürgen Schüttler, Christian Alzheimer, Jürgen Winkler, Barbara Namer, Beate Winner, Angelika Lampert
Publikováno v:
Stem Cell Reports, Vol 5, Iss 3, Pp 305-313 (2015)
Human pluripotent stem cells (hPSCs) offer the opportunity to generate neuronal cells, including nociceptors. Using a chemical-based approach, we generated nociceptive sensory neurons from HUES6 embryonic stem cells and retrovirally reprogrammed indu
Externí odkaz:
https://doaj.org/article/7b938d91ddc44b31834122252d74feb0
Autor:
Andreas M Kist, Dagrun Sagafos, Anthony M Rush, Cristian Neacsu, Esther Eberhardt, Roland Schmidt, Lars Kristian Lunden, Kristin Ørstavik, Luisa Kaluza, Jannis Meents, Zhiping Zhang, Thomas Hedley Carr, Hugh Salter, David Malinowsky, Patrik Wollberg, Johannes Krupp, Inge Petter Kleggetveit, Martin Schmelz, Ellen Jørum, Angelika Lampert, Barbara Namer
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0161789 (2016)
Gain-of-function mutations in the tetrodotoxin (TTX) sensitive voltage-gated sodium channel (Nav) Nav1.7 have been identified as a key mechanism underlying chronic pain in inherited erythromelalgia. Mutations in TTX resistant channels, such as Nav1.8
Externí odkaz:
https://doaj.org/article/0ff14342238441cca93dc92d429cbad3
Autor:
Cristian Neacsu, Alexandru Babes
Publikováno v:
Journal of Pharmacological Sciences, Vol 114, Iss 3, Pp 332-340 (2010)
Abstract.: Linopirdine is a well known blocker of voltage-gated potassium channels from the Kv7 (or KCNQ) family that generate the so called M current in mammalian neurons. Kv7 subunits are also expressed in pain-sensing neurons in dorsal root gangli
Externí odkaz:
https://doaj.org/article/a74c120edc7f4be19c18469ed343dc6d
Publikováno v:
Analele Universităţii "Dunărea de Jos" Galaţi: Fascicula III, Electrotehnică, Electronică, Automatică, Informatică, Vol 2005, Iss 1, Pp 44-52 (2005)
The most accessible interfaces querying databases must be so intelligent, able to understand natural language expressions and including vague terms in selection criteria. The paper proposes a general architecture for a flexible database interface and
Externí odkaz:
https://doaj.org/article/ac047133338441649a657f2866394bbb
Autor:
Cristian Neacsu, Tatjana I. Kichko, Peter W. Reeh, Tudor Selescu, Alexandra Manolache, Lisa Gebhardt, Alexandru Babes
Publikováno v:
European Journal of Pain. 25:122-135
Background PUVA (psoralen UVA) therapy is used to treat a variety of skin conditions, such as vitiligo psoriasis, eczema and mycosis fungoides, but it is frequently accompanied by phototoxicity leading to burning pain, itch and erythema. Methods We u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac10670972d972bb50df901258ca34c6
https://doi.org/10.1002/ejp.1654
https://doi.org/10.1002/ejp.1654
Autor:
Aura E. Ionescu, Alexandru Babes, G Larisa Maier, Tudor Selescu, Mihaela Mentel, Cristian Neacsu, Alexandra Manolache, Stefan E. Szedlacsek
Publikováno v:
Journal of Cellular Physiology. 235:5192-5203
The transient receptor potential melastatin type 8 (TRPM8) receptor channel is expressed in primary afferent neurons where it is the main transducer of innocuous cold temperatures and also in a variety of tumors, where it is involved in progression a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a40ab4ffa27407171ff5039a9c77b87
https://doi.org/10.1002/jcp.29397
https://doi.org/10.1002/jcp.29397
Autor:
Tobias Huth, Stefanie Bothe, Jannis E. Meents, Sarah Thull, Ralf Hausmann, Andrias O. O'Reilly, Angelika Lampert, Cristian Neacsu
Publikováno v:
Data in Brief
Data in Brief 31, 105844 (2020). doi:10.1016/j.dib.2020.105844
Data in Brief, Vol 31, Iss, Pp 105844-(2020)
Data in Brief 31, 105844 (2020). doi:10.1016/j.dib.2020.105844
Data in Brief, Vol 31, Iss, Pp 105844-(2020)
Data in Brief 31, 105844 (2020). doi:10.1016/j.dib.2020.105844
Published by Elsevier, Amsterdam [u.a.]
Published by Elsevier, Amsterdam [u.a.]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ea400397228a3e6cae2bae37d811959
http://europepmc.org/articles/PMC7329930
http://europepmc.org/articles/PMC7329930
Autor:
Angelika Lampert, Cristian Neacsu, Andrias O. O'Reilly, Sarah Thull, Ralf Hausmann, Tobias Huth, Jannis E. Meents, Stefanie Bothe
Publikováno v:
Toxicology and applied pharmacology. 397
Voltage-gated sodium channels are responsible not only for the fast upstroke of the action potential, but they also modify cellular excitability via persistent and resurgent currents. Insecticides act via permanently opening sodium channels to immobi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23e7ae4d656d0087e7be54ffcf5eacbd
https://pubmed.ncbi.nlm.nih.gov/32302602
https://pubmed.ncbi.nlm.nih.gov/32302602