Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Cristian G Bologa"'
Autor:
LynnMarie Jarratt, Jenny Situ, Rachel D King, Estefania Montanez Ramos, Hannah Groves, Ryen Ormesher, Melissa Cossé, Alyse Raboff, Avanika Mahajan, Jennifer Thompson, Randy F Ko, Samantha Paltrow-Krulwich, Allison Price, Ariel May-Ling Hurwitz, Timothy CampBell, Lauren T Epler, Fiona Nguyen, Emma Wolinsky, Morgan Edwards-Fligner, Jolene Lobo, Danielle Rivera, Jens Langsjoen, Lori Sloane, Ingrid Hendrix, Elly O Munde, Clinton O Onyango, Perez K Olewe, Samuel B Anyona, Alexandra V Yingling, Nicolas R Lauve, Praveen Kumar, Shawn Stoicu, Anastasiya Nestsiarovich, Cristian G Bologa, Tudor I Oprea, Kristine Tollestrup, Orrin B Myers, Mari Anixter, Douglas J Perkins, Christophe Gerard Lambert
Publikováno v:
JMIR Medical Education, Vol 8, Iss 1, p e23845 (2022)
BackgroundOn March 11, 2020, the New Mexico Governor declared a public health emergency in response to the COVID-19 pandemic. The New Mexico medical advisory team contacted University of New Mexico (UNM) faculty to form a team to consolidate growing
Externí odkaz:
https://doaj.org/article/bf5ae633455a4866b0bb324a9a5889af
Autor:
Kishore Polireddy, Mohiuddin Md Taimur Khan, Hemantkumar Chavan, Susan Young, Xiaochao Ma, Anna Waller, Matthew Garcia, Dominique Perez, Stephanie Chavez, Jacob J Strouse, Mark K Haynes, Cristian G Bologa, Tudor I Oprea, George P Tegos, Larry A Sklar, Partha Krishnamurthy
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40005 (2012)
ABCB6 is a member of the adenosine triphosphate (ATP)-binding cassette family of transporter proteins that is increasingly recognized as a relevant physiological and therapeutic target. Evaluation of modulators of ABCB6 activity would pave the way to
Externí odkaz:
https://doaj.org/article/47f376b04fb948fba53161f649e4c7f5
Autor:
Cristian G. Bologa, Vernon Shane Pankratz, Mark L. Unruh, Maria Eleni Roumelioti, Vallabh Shah, Saeed Kamran Shaffi, Soraya Arzhan, John Cook, Christos Argyropoulos
Publikováno v:
BMC Medical Research Methodology, Vol 21, Iss 1, Pp 1-24 (2021)
Abstract Background Converting electronic health record (EHR) entries to useful clinical inferences requires one to address the poor scalability of existing implementations of Generalized Linear Mixed Models (GLMM) for repeated measures. The major co
Externí odkaz:
https://doaj.org/article/256cf2dde7144aa186d0db38237035a2
Autor:
Sorin Avram, Thomas B Wilson, Ramona Curpan, Liliana Halip, Ana Borota, Alina Bora, Cristian G Bologa, Jayme Holmes, Jeffrey Knockel, Jeremy J Yang, Tudor I Oprea
Publikováno v:
Nucleic Acids Research. 51:D1276-D1287
DrugCentral monitors new drug approvals and standardizes drug information. The current update contains 285 drugs (131 for human use). New additions include: (i) the integration of veterinary drugs (154 for animal use only), (ii) the addition of 66 do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77adc096b9afda5df0f59b380b846253
https://doi.org/10.1093/nar/gkac1085
https://doi.org/10.1093/nar/gkac1085
Autor:
Keith J Kelleher, Timothy K Sheils, Stephen L Mathias, Jeremy J Yang, Vincent T Metzger, Vishal B Siramshetty, Dac-Trung Nguyen, Lars Juhl Jensen, Dušica Vidović, Stephan C Schürer, Jayme Holmes, Karlie R Sharma, Ajay Pillai, Cristian G Bologa, Jeremy S Edwards, Ewy A Mathé, Tudor I Oprea
Publikováno v:
Kelleher, K J, Sheils, T K, Mathias, S L, Yang, J J, Metzger, V T, Siramshetty, V B, Nguyen, D-T, Jensen, L J, Vidovic, D, Schurer, S C, Holmes, J, Sharma, K R, Pillai, A, Bologa, C G, Edwards, J S, Mathe, E A & Oprea, T 2023, ' Pharos 2023 : an integrated resource for the understudied human proteome ', Nucleic Acids Research, vol. 51, no. D1, gkac1033, pp. D1405-D1416 . https://doi.org/10.1093/nar/gkac1033
The Illuminating the Druggable Genome (IDG) project aims to improve our understanding of understudied proteins and our ability to study them in the context of disease biology by perturbing them with small molecules, biologics, or other therapeutic mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d65450ea96a731b4d232b473fbf4326
https://curis.ku.dk/portal/da/publications/pharos-2023(f032f17b-c49b-4c10-9eb3-36e30874c00f).html
https://curis.ku.dk/portal/da/publications/pharos-2023(f032f17b-c49b-4c10-9eb3-36e30874c00f).html
Autor:
John Erol Evangelista, Daniel J. B. Clarke, Zhuorui Xie, Giacomo B. Marino, Vivian Utti, Taha M. Ahooyi, Sherry L. Jenkins, Deanne Taylor, Cristian G. Bologa, Jeremy J. Yang, Jessica L. Binder, Praveen Kumar, Christophe G. Lambert, Jeffrey S. Grethe, Eric Wenger, Tudor I. Oprea, Bernard de Bono, Avi Ma’ayan
Birth defects are functional and structural abnormalities that impact 1 in 33 births in the United States. Birth defects have been attributed to genetic as well as other factors, but for most birth defects there are no known causes. Small molecule dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36fcaf7345434da03c63ea9da88c526f
https://doi.org/10.1101/2022.09.15.508198
https://doi.org/10.1101/2022.09.15.508198
Autor:
Eryk Kropiwnicki, Jessica L. Binder, Jeremy J. Yang, Jayme Holmes, Alexander Lachmann, Daniel J. B. Clarke, Timothy Sheils, Keith J. Kelleher, Vincent T. Metzger, Cristian G. Bologa, Tudor I. Oprea, Avi Ma'ayan
Publikováno v:
Current Protocols. 2
The Illuminating the Druggable Genome (IDG) consortium is a National Institutes of Health (NIH) Common Fund program designed to enhance our knowledge of under-studied proteins, more specifically, proteins unannotated within the three most commonly dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e53d391a4c0ca33b04fd8138d9b5618
https://doi.org/10.1002/cpz1.355
https://doi.org/10.1002/cpz1.355
Autor:
Suzanne Ackloo, Rima Al-awar, Rommie E. Amaro, Cheryl H. Arrowsmith, Hatylas Azevedo, Robert A. Batey, Yoshua Bengio, Ulrich A.K. Betz, Cristian G. Bologa, John D. Chodera, Wendy D. Cornell, Ian Dunham, Gerhard F. Ecker, Kristina Edfeldt, Aled M. Edwards, Michael K. Gilson, Claudia R. Gordijo, Gerhard Hessler, Alexander Hillisch, Anders Hogner, John J. Irwin, Johanna M. Jansen, Daniel Kuhn, Andrew R. Leach, Alpha A. Lee, Uta Lessel, John Moult, Ingo Muegge, Tudor I. Oprea, Benjamin G. Perry, Patrick Riley, Kumar Singh Saikatendu, Vijayaratnam Santhakumar, Matthieu Schapira, Cora Scholten, Matthew H. Todd, Masoud Vedadi, Andrea Volkamer, Timothy M. Willson
Computational approaches in drug discovery and development hold great promise, with artificial intelligence methods undergoing widespread contemporary use, but the experimental validation of these new approaches is frequently inadequate. We are initi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14ff20377f97c4f069e09484e87a7f2c
https://doi.org/10.26434/chemrxiv-2021-rzq4n
https://doi.org/10.26434/chemrxiv-2021-rzq4n
Autor:
LynnMarie Jarratt, Jenny Situ, Rachel D King, Estefania Montanez Ramos, Hannah Groves, Ryen Ormesher, Melissa Cossé, Alyse Raboff, Avanika Mahajan, Jennifer Thompson, Randy F Ko, Samantha Paltrow-Krulwich, Allison Price, Ariel May-Ling Hurwitz, Timothy CampBell, Lauren T Epler, Fiona Nguyen, Emma Wolinsky, Morgan Edwards-Fligner, Jolene Lobo, Danielle Rivera, Jens Langsjoen, Lori Sloane, Ingrid Hendrix, Elly O Munde, Clinton O Onyango, Perez K Olewe, Samuel B Anyona, Alexandra V Yingling, Nicolas R Lauve, Praveen Kumar, Shawn Stoicu, Anastasiya Nestsiarovich, Cristian G Bologa, Tudor I Oprea, Kristine Tollestrup, Orrin B Myers, Mari Anixter, Douglas J Perkins, Christophe Gerard Lambert
BACKGROUND On March 11, 2020, the New Mexico Governor declared a public health emergency in response to the COVID-19 pandemic. The New Mexico medical advisory team contacted University of New Mexico (UNM) faculty to form a team to consolidate growing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a4a56d7fe5d9fc31aa5d2203a6ce264
https://doi.org/10.2196/preprints.23845
https://doi.org/10.2196/preprints.23845
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1939
Virtual screening is a well-established technique that has proven to be successful in the identification of novel biologically active molecules, including drug repurposing. Whether for ligand-based or for structure-based virtual screening, a chemical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::44ae83c2f3eb465227dd7c824b36f0d6
https://pubmed.ncbi.nlm.nih.gov/30848459
https://pubmed.ncbi.nlm.nih.gov/30848459