Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Cristian E. Leyton"'
Autor:
Sanka Amadoru, Vincent Doré, Catriona A. McLean, Fairlie Hinton, Claire E. Shepherd, Glenda M. Halliday, Cristian E. Leyton, Paul A. Yates, John R. Hodges, Colin L. Masters, Victor L. Villemagne, Christopher C. Rowe
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-8 (2020)
Abstract Background The Centiloid scale was developed to standardise the results of beta-amyloid (Aβ) PET. We aimed to determine the Centiloid unit (CL) thresholds for CERAD sparse and moderate-density neuritic plaques, Alzheimer’s disease neuropa
Externí odkaz:
https://doaj.org/article/cc27d92619bd4230adff490e4b06e8ab
Autor:
Zoë-Lee Goldberg, Hashim El-Omar, David Foxe, Cristian E. Leyton, Rebekah M. Ahmed, Olivier Piguet, Muireann Irish
Publikováno v:
Brain Sciences, Vol 11, Iss 12, p 1600 (2021)
Mounting evidence suggests that, in parallel with well-defined changes in language, primary progressive aphasia (PPA) syndromes display co-occurring social cognitive impairments. Here, we explored multidimensional profiles of carer-rated social commu
Externí odkaz:
https://doaj.org/article/58b184863fcd44088b64ebc240fd4733
Autor:
Thuy Anh Sally Nguyen, Nichol Castro, Michael S. Vitevitch, Annabel Harding, Renata Teng, Joanne Arciuli, Cristian E. Leyton, Olivier Piguet, Kirrie J. Ballard
Publikováno v:
International journal of speech-language pathology.
Purpose: Speed and accuracy of lexical access change with healthy ageing and neurodegeneration. While a word's immediate phonological neighbourhood density (i.e. words differing by a single phoneme) influences access, connectivity to all words in the
Autor:
Fiona Kumfor, Cheng Tao Liang, Jessica L. Hazelton, Cristian E. Leyton, Cassandra Kaizik, Emma Devenney, Emily Connaughton, Robyn Langdon, Eneida Mioshi, John B. Kwok, Carol Dobson‐Stone, Glenda M. Halliday, Olivier Piguet, John R. Hodges, Ramon Landin‐Romero
Publikováno v:
International Journal of Geriatric Psychiatry. 37
Objectives Abnormal beliefs and delusions have been reported in some people with dementia, however, the prevalence of delusions, and their neurocognitive basis has been underexplored. This study aimed to examine the presence, severity, content and ne
Autor:
David Foxe, Olivier Piguet, Zoë-Lee Goldberg, Hashim El-Omar, Rebekah M. Ahmed, Cristian E. Leyton, Muireann Irish
Publikováno v:
Brain Sciences; Volume 11; Issue 12; Pages: 1600
Brain Sciences, Vol 11, Iss 1600, p 1600 (2021)
Brain Sciences
Brain Sciences, Vol 11, Iss 1600, p 1600 (2021)
Brain Sciences
Mounting evidence suggests that, in parallel with well-defined changes in language, primary progressive aphasia (PPA) syndromes display co-occurring social cognitive impairments. Here, we explored multidimensional profiles of carer-rated social commu
Autor:
Cheng T. Liang, Kirrie J. Ballard, Penelope Monroe, John R. Hodges, Olivier Piguet, Yuichi Higashiyama, Cristian E. Leyton, Ramon Landin-Romero
Publikováno v:
Brain Communications
Aquired apraxia of speech is a disorder that impairs speech production, despite intact peripheral neuromotor function. Its pathomechanism remains to be established. Neurodegenerative lesion models provide an unequalled opportunity to explore the neur
Publikováno v:
Neurocase. 26(3)
Six patients with equivocal amyloid-PET results are discussed.Patients underwent clinical/neuropsychological assessment, MRI, and amyloid-PET. Equivocal amyloid-PET was defined as cortical ligand binding with SUVR1.40. Follow-up for up to 5 years is
Autor:
Ahmad Reza Khatoonabadi, Cristian E. Leyton, John R. Hodges, Maryam Noroozian, Amin Modarresszadeh, Salime Jafari, Noureddin Nakhostin Ansari
Publikováno v:
Basic and Clinical Neuroscience
Basic and Clinical Neuroscience, Vol 9, Iss 1, Pp 35-42 (2018)
Scopus-Elsevier
Basic and Clinical Neuroscience, Vol 9, Iss 1, Pp 35-42 (2018)
Scopus-Elsevier
Introduction: Primary Progressive Aphasia (PPA) is a neurological condition characterized by progressive dissolution of language capabilities. The Progressive Aphasia Language Scale (PALS) is an easy-to-apply bedside clinical scale capable of capturi
Autor:
Cristian E. Leyton, Fiona Kumfor, John R. Hodges, Olivier Piguet, Muireann Irish, Ramon Landin-Romero
Publikováno v:
NeuroImage. 151:72-80
Background Clinical differentiation between Alzheimer's disease (AD) and behavioural-variant frontotemporal dementia (bvFTD) is challenging due to overlapping clinical features at presentation. Whilst diagnostic criteria for both disorders incorporat
Publikováno v:
Cortex. 86:45-54
The majority of logopenic variant primary progressive aphasia (lv-PPA) cases harbour Alzheimer pathology, suggesting that lv-PPA constitutes an atypical presentation of Alzheimer's disease (AD). However, even if caused by Alzheimer pathology, the cli