Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Cristian Aparicio-Maldonado"'
Autor:
Jack P. K. Bravo, Cristian Aparicio-Maldonado, Franklin L. Nobrega, Stan J. J. Brouns, David W. Taylor
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
DISARM (Defense Island System Associated with Restriction Modification) systems can provide bacteria with protection against a wide range of phage. Here, Bravo et al. determine cryo-EM structures of the core DISARM complex that shed light onto phage
Externí odkaz:
https://doaj.org/article/dced8bd6877849529f57e7386dedd6cf
Autor:
Alex N Salazar, Franklin L Nobrega, Christine Anyansi, Cristian Aparicio-Maldonado, Ana Rita Costa, Anna C Haagsma, Anwar Hiralal, Ahmed Mahfouz, Rebecca E McKenzie, Teunke van Rossum, Stan J J Brouns, Thomas Abeel
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 1, p e1007314 (2020)
The last decade has witnessed a remarkable increase in our ability to measure genetic information. Advancements of sequencing technologies are challenging the existing methods of data storage and analysis. While methods to cope with the data deluge a
Externí odkaz:
https://doaj.org/article/6f872a9771584b79a7dacbeed69d8275
Autor:
Modesto Redrejo-Rodríguez, Carlos D. Ordóñez, Mónica Berjón-Otero, Juan Moreno-González, Cristian Aparicio-Maldonado, Patrick Forterre, Margarita Salas, Mart Krupovic
Publikováno v:
Cell Reports, Vol 21, Iss 6, Pp 1574-1587 (2017)
Summary: Family B DNA polymerases (PolBs) play a central role during replication of viral and cellular chromosomes. Here, we report the discovery of a third major group of PolBs, which we denote primer-independent PolB (piPolB), that might be a link
Externí odkaz:
https://doaj.org/article/41f495adcdde458ab33b5a430e23ff58
Autor:
Cristian Aparicio-Maldonado, Gal Ofir, Andrea Salini, Rotem Sorek, Franklin L. Nobrega, Stan J.J. Brouns
Bacteriophages impose a strong evolutionary pressure on microbes for the development of mechanisms of survival. Multiple new mechanisms of innate defense have been described recently, with the molecular mechanism of most of them remaining uncharacter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::513c577be965f6e63648a79800ec15ae
https://doi.org/10.1101/2021.12.28.474362
https://doi.org/10.1101/2021.12.28.474362
Autor:
Ana Rita Costa, Cristian Aparicio-Maldonado, Julia E Egido, Pieter-Jan A. Haas, Stan J. J. Brouns
Publikováno v:
FEMS Microbiology Reviews. 46
We are in the midst of a golden age of uncovering defense systems against bacteriophages. Apart from the fundamental interest in these defense systems, and revolutionary applications that have been derived from them (e.g. CRISPR-Cas9 and restriction
Autor:
Thomas Abeel, Cristian Aparicio-Maldonado, Anwar Hiralal, Ana Rita Costa, Anna C. Haagsma, Stan J. J. Brouns, Ahmed Mahfouz, Teunke van Rossum, Alex N. Salazar, Christine Anyansi, Franklin L. Nobrega, Rebecca E. McKenzie
Publikováno v:
PLOS Computational Biology
PLoS Computational Biology
PLoS Computational Biology, Vol 16, Iss 1, p e1007314 (2020)
PLoS Computational Biology (Print), 16(1)
PLoS Computational Biology
PLoS Computational Biology, Vol 16, Iss 1, p e1007314 (2020)
PLoS Computational Biology (Print), 16(1)
The last decade has witnessed a remarkable increase in our ability to measure genetic information. Advancements of sequencing technologies are challenging the existing methods of data storage and analysis. While methods to cope with the data deluge a