Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Cristian Angeli"'
Autor:
Cristian Angeli, Joanna Patrycja Wroblewska, Eliane Klein, Christiane Margue, Stephanie Kreis
Publikováno v:
STAR Protocols, Vol 5, Iss 2, Pp 103058- (2024)
Summary: Three-dimensional (3D) models play an increasingly important role in preclinical drug testing as they faithfully mimic interactions between cancer cells and the tumor microenvironment (TME). Here, we present a protocol for generating scaffol
Externí odkaz:
https://doaj.org/article/f8bb9a77fedc4b87a3f942be873eeec2
Autor:
Luise Dunsche, Nikita Ivanisenko, Shamala Riemann, Sebastian Schindler, Stefan Beissert, Cristian Angeli, Stephanie Kreis, Mahvash Tavassoli, Inna Lavrik, Dagmar Kulms
Publikováno v:
Cell Death and Disease, Vol 14, Iss 12, Pp 1-12 (2023)
Abstract Malignant melanoma (MM) is known to be intrinsically chemoresistant, even though only ~20% of MM carry mutations of the tumor suppressor p53. Despite improvement of systemic therapy the mortality rate of patients suffering from metastatic MM
Externí odkaz:
https://doaj.org/article/a2981f85ff5e4563ac4ee7b07352b383
Autor:
Vincent Gureghian, Hailee Herbst, Ines Kozar, Katarina Mihajlovic, Noël Malod-Dognin, Gaia Ceddia, Cristian Angeli, Christiane Margue, Tijana Randic, Demetra Philippidou, Milène Tetsi Nomigni, Ahmed Hemedan, Leon-Charles Tranchevent, Joseph Longworth, Mark Bauer, Apurva Badkas, Anthoula Gaigneaux, Arnaud Muller, Marek Ostaszewski, Fabrice Tolle, Nataša Pržulj, Stephanie Kreis
Therapy Induced Senescence (TIS) leads to sustained growth arrest of cancer cells. The associated cytostasis has been shown to be reversible and cells escaping senescence further enhance the aggressiveness of cancers. Together with targeted therapeut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfc6e5557f14569079e2e1e54f858f28
https://doi.org/10.1101/2023.02.13.528114
https://doi.org/10.1101/2023.02.13.528114
Publikováno v:
Sait, A, Angeli, C, Doig, A J & Day, P J R 2021, ' Viral Involvement in Alzheimer’s Disease ', ACS Chemical Neuroscience . https://doi.org/10.1021/acschemneuro.0c00719
ACS Chemical Neuroscience
ACS Chemical Neuroscience
Alzheimer's disease (AD) is characterized by the presence of β-amyloid plaques (Aβ) and neurofibrillary tangles (NFTs) in the brain. The prevalence of the disease is increasing and is expected to reach 141 million cases by 2050. Despite the risk fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9333c2f3cbc161b071779b4b9a7357b0
https://doi.org/10.1021/acschemneuro.0c00719
https://doi.org/10.1021/acschemneuro.0c00719
Publikováno v:
Veterinary pathology. 58(2)
Using immunohistochemistry, 170 canine mammary carcinomas were evaluated for p53, ER (estrogen receptor), and Ki67. Of the 170 tumors, 89 were grade I (52.3%), 36 were grade II (21.2%), and 45 were grade III (26.4%). Eight cases (0.5%) were positive