Výsledky vyhledávání - "Cristian Alberto Ferri"

Alteraciones genéticas y epi-genéticas del gen PTEN : clave en la relación entre diabetes mellitus tipo 2 y cáncer

Autor: Alan Rolando Ayala Schimpf, María Mercedes Formichela, María Betania Mascheroni, Donovan Rivero, Marcela Luján Chamorro, Valeria Portillo, Pedro Darío Zapata, Cristian Alberto Ferri

Publikováno v: Revista de Ciencia y Tecnología (Misiones), 6-2022; 37(1): pp. 73–80 https://www.fceqyn.unam.edu.ar/recyt/index.php/recyt
Repositorio Institucional Digital de la Universidad Nacional de Misiones (UNaM)
Universidad Nacional de Misiones
instacron:UNAM

Fil: Ayala Schimpf, Alan Rolando. Universidad Nacional de Misiones. Facultad de Ciencias Exactas, Químicas y Naturales. Instituto de Biotecnología Misiones “Dra. María Ebe Reca”. Laboratorio de Biotecnología Molecular; Argentina. Fil: Chamorr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3bd46849c6667cc958d49ec6c524a3b

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The dynamic of TNF and IL6 gene expression in chronic myeloid leukemia patients reveals early responders to imatinib

Autor: Cristian Alberto Ferri, Yesica Soledad Bestach, Irene Larripa, Maria Jazmin Ayelen Toloza, Carolina Bárbara Belli

Publikováno v: Repositorio Institucional Digital de la Universidad Nacional de Misiones (UNaM)
Universidad Nacional de Misiones
instacron:UNAM

Imatinib, the first BCR-ABL1 tyrosine kinase inhibitor (TKI), revolutionized the management of chronic myeloid leukemia (CML) and remains as the preferred first-line therapy for newly diagnosed patients [1]. Besides its direct onco-kinase inhibition,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac5e0b39f1a3e5e962fc76e2e0f0991e
https://www.sciencedirect.com/science/article/abs/pii/S0145212619301663

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Asymptomatic dengue virus cases in misiones, Argentina: a seroprevalence study in the university population

Autor: Pedro Darío Zapata, José Ricardo Valdez, Graciela Noemí Malvasi, María Mercedes Formichela, Elba Cristina Malarczuk, Graciela Viviana Dusse, Ivana Magalí Rocío Medina, Cristian Alberto Ferri

Publikováno v: Microbes and infection. 21(3-4)

Dengue infection may be asymptomatic and may produce the typical symptoms of a benign illness or serious hemorrhagic and often fatal symptoms. Asymptomatic cases are statistically relevant and quite variable depending on the geographic area under stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be07bf816ddd148091951c2e7278623f
https://pubmed.ncbi.nlm.nih.gov/30668989

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GSTM1 and GSTP1, but not GSTT1 genetic polymorphisms are associated with chronic myeloid leukemia risk and treatment response

Autor: Isabel Giere, Natalia Weich, Ariela Freya Fundia, Irene Larripa, Carolina Pavlovsky, Cristian Alberto Ferri, Beatriz Moiraghi, Raquel Bengió

Background: Chronic myeloid leukemia (CML) is associated to the BCR-ABL1 oncogene and can successfully be treated with tyrosine kinase inhibitors (TKIs). However, it remains still under investigation which molecular factors may influence CML risk or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::914cbf2494986405c36e96fb693bea8a
https://www.sciencedirect.com/science/article/pii/S1877782116300947

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TP53 codon 72 polymorphism predicts chronic myeloid leukemia susceptibility and treatment outcome

Autor: Ariela Freya Fundia, Beatriz Moiraghi, Carolina Pavlovsky, Raquel Bengió, Cristian Alberto Ferri, Irene Larripa, Isabel Giere, Natalia Weich

BCR-ABL1 gene is a key molecular marker of chronic myeloid leukemia (CML), but it is still unclear which molecular factors may influence CML risk or lead to variable responses to tyrosine kinase inhibitors (TKIs). The aim of this study was to investi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7efbd2911884fea629c047cdb912907b
https://www.sciencedirect.com/science/article/pii/S1079979616300559

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Early detection and quantification of mutations in the tyrosine kinase domain of chimericalBCR–ABL1gene combining high-resolution melting analysis and mutant-allele specific quantitative polymerase chain reaction

Autor: Raquel Bengió, Cristian Alberto Ferri, Carolina Bárbara Belli, Gustavo Damián Icardi, Michele Bianchini, Irene Larripa

Publikováno v: Leukemia & Lymphoma. 54:598-606

BCR–ABL1 point mutations are the most common cause of resistance in patients with chronic myeloid leukemia (CML) who fail or lose response to tyrosine kinase inhibitors. We have developed a rapid method to screen BCR–ABL1 mutations by high resolu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29eada3cd92b99ec7c2695f3aa47ed8
https://doi.org/10.3109/10428194.2012.718767

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Clinical activity of ponatinib in one patient with chronic myeloid leukemia in chronic phase with e19a2 transcript and T315I mutation

Autor: Raquel Bengió, Elena Beatriz Moiraghi, Cristian Alberto Ferri, Mariana Selena Gonzalez, Irene Larripa, Michele Bianchini, Maria Fernanda Noriega

Background: Chronic myeloid leukemia (CML) is a hematological disorder that in rare cases, mainly in CML neutrophilic, presents the e19a2 rearrangement. The encoded product is a 230-KDa protein. Despite the remarkable responses to treatment of most p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e4057ffe85c2a9dc30ebf1ee4194d8a
Wiley Online Library

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CAMKIIγ, HSP70 and HSP90 transcripts are differentially expressed in chronic myeloid leukemia cells from patients with resistant mutated disease

Autor: Irene Larripa, Carlos Daniel de Brasi, Mariana Gonzalez, Raquel Bengió, Cristian Alberto Ferri, Michele Bianchini

Publikováno v: Leukemialymphoma. 55(9)

Patients with chronic myeloid leukemia (CML) can develop disease resistance to tyrosine kinase inhibitor (TKI) therapy, which is mainly attributable to the presence of point mutations in the tyrosine kinase domain of BCR–ABL1. In order to examine s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64ba46e5d4a70db9157f1f1bfaa6645f
https://pubmed.ncbi.nlm.nih.gov/24206096

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Expression of LYN and PTEN genes in chronic myeloid leukemia and their importance in therapeutic strategy

Autor: Cristian Alberto Ferri, Irene Larripa, Raquel Bengió, Michele Bianchini

Tyrosine kinase inhibitors (TKIs), imatinib, nilotinib and dasatinib, are the current treatment of chronic myeloid leukemia (CML). BCR-ABL1 point mutations are the principal cause of resistance to treatment; however other mechanisms could be involved

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1e06538fb12de6ee914c9f86bd80a7f
http://www.sciencedirect.com/science/article/pii/S1079979613002064

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New mutation L324M in the ABL1 kinase domain: does it confer high resistance to second-generation inhibitors?

Autor: Jorge Korin, Cristian Alberto Ferri, Eduardo Bullorsky, Maria Fernanda Noriega, Irene Larripa, Gustavo Icardi

Publikováno v: Leukemialymphoma. 55(3)

In chronic myeloid leukemia (CML) the presence of mutations in the tyrosine kinase domain (TK) of the normalABL1 gene is the most common cause of loss of response to treatment. Detection of these mutations is an important study because it allows the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c4e337da05f8de70c6900f4a5bab81
https://pubmed.ncbi.nlm.nih.gov/23741973

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