Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Cristian, Thom"'
Autor:
Yann Waltenspühl, Janosch Ehrenmann, Santiago Vacca, Cristian Thom, Ohad Medalia, Andreas Plückthun
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Here, Waltenspühl et al. report the cryo-EM structure of active human oxytocin receptor in complex with oxytocin and with a heterotrimeric G protein, providing insights into this hormone system critically involved in the regulation of social behavio
Externí odkaz:
https://doaj.org/article/5e8642019ba84ce2809030eeaafcf0db
Autor:
Markus Schmid, Patrick Ernst, Annemarie Honegger, Maarit Suomalainen, Martina Zimmermann, Lukas Braun, Sarah Stauffer, Cristian Thom, Birgit Dreier, Matthias Eibauer, Anja Kipar, Viola Vogel, Urs F. Greber, Ohad Medalia, Andreas Plückthun
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Viral gene therapy can be limited by the efficacy of virion sequestration, immune responses and the silencing of genetic payloads. Here the authors engineer an advenovirus protein coat which shields the virion from the immune system while targeting c
Externí odkaz:
https://doaj.org/article/00949421a2154bc48f4b16eaea93bece
Autor:
Cristian, Thom, Janosch, Ehrenmann, Santiago, Vacca, Yann, Waltenspühl, Jendrik, Schöppe, Ohad, Medalia, Andreas, Plückthun
Publikováno v:
Science Advances
Description
Neuropeptide-bound NK1R:G protein complex structures explain mechanisms ranging from insurmountable antagonism to activation.
The neurokinin 1 receptor (NK1R) is involved in inflammation and pain transmission. This pathophysiolo
Neuropeptide-bound NK1R:G protein complex structures explain mechanisms ranging from insurmountable antagonism to activation.
The neurokinin 1 receptor (NK1R) is involved in inflammation and pain transmission. This pathophysiolo
Autor:
Viola Vogel, Cristian Thom, Urs F. Greber, Matthias Eibauer, Annemarie Honegger, Ohad Medalia, Patrick Ernst, Martina Zimmermann, Andreas Plückthun, Sarah Stauffer, Anja Kipar, Markus Schmid, Birgit Dreier, Lukas Braun, Maarit Suomalainen
Publikováno v:
Nature Communications, 9
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Most systemic viral gene therapies have been limited by sequestration and degradation of virions, innate and adaptive immunity, and silencing of therapeutic genes within the target cells. Here we engineer a high-affinity protein coat, shielding the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfc9a6deb8899d7770964b73a9b3a610
https://hdl.handle.net/20.500.11850/239860
https://hdl.handle.net/20.500.11850/239860