Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Cristian, Constantinescu"'
Publikováno v:
Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Horticulture, Vol 76, Iss 1, Pp 96-105 (2019)
The study aimed to development a prediction model for soil erosion degree by image analysis techniques. The spectral information was obtained by image analysis in the RGB and HSB color system, and by calculus resulted rgb normalized values. Specific
Externí odkaz:
https://doaj.org/article/fb88e8e77d7e43bfac87266e7d476a7f
Publikováno v:
SEA: Practical Application of Science, Vol V, Iss 13 (1/2017), Pp 191-197 (2017)
Identifying the sources of conflict in a supply chain is the starting point of managing conflicts along chain and initiating the proper actions for lasting outcomes. An extended review of literature on sources of supply chain conflict was concluded w
Externí odkaz:
https://doaj.org/article/aa548f79360147fbb735fa5824537568
Publikováno v:
Cross-Cultural Management Journal, Vol XVII, Iss 2, Pp 161-173 (2015)
The paper proposes a new perspective that explains the convergence toward an increasingly smaller number of languages in communication between speakers of different native languages: the "vocation of language for international communication". For the
Externí odkaz:
https://doaj.org/article/a1af7c0d582e43ec8adec2efbd8bcd86
Autor:
Sandra Sanabria Bohorquez, Cristian Constantinescu, Paul T Manser, Roger N Gunn, David S Russell, Matteo Tonietto, Santiago Bullich, Andrew W Stephens, Andre Mueller, Gregory Klein, Edmond Teng, Karen Pickthorn
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c013ed02a98a17e514c717516af4785f
https://doi.org/10.1002/alz.063513
https://doi.org/10.1002/alz.063513
Autor:
Cristian Constantinescu, David Alagille, Caroline Papin, Eiji Sunahara, Shuhei Ikeda, Tatsuki Koike, Maki Miyamoto, John Seibyl, Gilles Tamagnan, Olivier Barret, Thomas J. Morley, Krista Fowles, Patricia E. Cole, Takanobu Kuroita, Toshiya Nishi
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 49:1148-1156
Purpose Cholesterol 24-hydroxylase (CH24H) is a brain-specific enzyme that plays a major role in brain cholesterol homeostasis by converting cholesterol into 24S-hydroxycholesterol. The selective CH24H inhibitor soticlestat (TAK-935) is being pursued
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c3b49ad503abe1c9b276111d06b8346
https://doi.org/10.1007/s00259-021-05565-z
https://doi.org/10.1007/s00259-021-05565-z
Autor:
Florin Teisanu, Constantin Chelan, Marinela Butoi, Marcel Nicola, Claudiu-Ionel Nicola, Daniela Iovan, Alin Neagoe, Cristian Constantinescu
Publikováno v:
2022 International Conference and Exposition on Electrical And Power Engineering (EPE).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d39f05563763137dca13c1e254c1c73d
https://doi.org/10.1109/epe56121.2022.9959832
https://doi.org/10.1109/epe56121.2022.9959832
Autor:
David Alagille, Satoru Matsuda, Rina Baba, Gilles Tamagnan, Thomas J. Morley, Yasushi Hattori, Tatsuki Koike, Caroline Papin, Cristian Constantinescu, Alexandra Gouasmat, Vincent M. Carroll, Shinji Iwasaki, Kouta Matsumiya
Publikováno v:
Journal of Medicinal Chemistry. 64:3780-3793
Dysregulation of histone H3 lysine 4 (H3K4) methylation is implicated in the pathogenesis of neurodevelopmental disorders. Lysine-specific demethylase 1 (LSD1) determines the methylation status of H3K4 through flavin adenine dinucleotide (FAD)-mediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db440a3e94e4141daeec35dfc6807678
https://doi.org/10.1021/acs.jmedchem.0c01937
https://doi.org/10.1021/acs.jmedchem.0c01937
Autor:
Vincent M. Carroll, David Gray, John Seibyl, Olivier Barret, Gilles Tamagnan, Timothy J. McCarthy, Lei Zhang, Jenna M. Sullivan, David Alagille, Caroline Papin, Christine M. Sandiego, Cristian Constantinescu, Jianqing Chen, Anabella Villalobos, Thomas J. Morley, Chewah Lee
Publikováno v:
Journal of Nuclear Medicine. 62:1307-1313
Non–catechol-based high-affinity selective dopamine D1 receptor (D1R) agonists were recently described, and candidate PET ligands were selected on the basis of favorable properties. The objective of this study was to characterize in vivo in nonhuma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab34abe7cd7c382705fc60cac95e5e16
https://doi.org/10.2967/jnumed.120.256008
https://doi.org/10.2967/jnumed.120.256008
Autor:
Vincent M. Carroll, Daniel Holden, Seth C. Hopkins, Kenneth S. Koblan, Robert Lew, Richard E. Carson, Cristian Constantinescu, Gerald Galluppi
Publikováno v:
Psychopharmacology
Rationale Drugs that rapidly increase dopamine levels have an increased risk of abuse. Dasotraline (DAS) is a dopamine and norepinephrine reuptake inhibitor characterized by slow oral absorption with low potential for abuse. However, it remains uncle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a586bc8ca7b073b49e53f009299cf8ad
http://europepmc.org/articles/PMC7651685
http://europepmc.org/articles/PMC7651685
Autor:
David S. Russell, Cristian Constantinescu, Olivier Barret, Mark E. Schmidt, Diederik Moechars, Maarten Timmers, Frederik J. R. Rombouts, Hartmuth C. Kolb, Luc Janssens, Christine M. Sandiego, Jennifer Madonia
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 47:3176-3185
Purpose The accumulation of misfolded tau is a common feature of several neurodegenerative disorders, with Alzheimer’s disease (AD) being the most common. Earlier we identified JNJ-64326067, a novel isoquinoline derivative with high affinity and se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec7e3229648e38b441d0ddf4ee69be04
https://doi.org/10.1007/s00259-020-04880-1
https://doi.org/10.1007/s00259-020-04880-1