Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Cristi R, King"'
Autor:
Kathryn J. Lindley, Nita A. Limdi, Larisa H. Cavallari, Minoli A. Perera, Petra Lenzini, Julie A. Johnson, Alan H. B. Wu, Paul M Ridker, Cristi R. King, Charles S. Eby, Shitalben Patel, Shimoli V. Shah, T. Mark Beasley, Juan Li, Brian F. Gage
Publikováno v:
Clinical Pharmacology & Therapeutics. 111:950-955
Pharmacogenetic dosing improves the accuracy of warfarin dosing, but current pharmacogenetic dosing algorithms are less accurate in populations of African ancestry. The cytochrome P450 2C9*5 (CYP2C9*5) allele is found almost exclusively in population
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166a0db23d78d0a645b39f79acb7f845
https://doi.org/10.1002/cpt.2549
https://doi.org/10.1002/cpt.2549
Autor:
Michael M. Binkley, Micah Iticovici, Cristi R. King, William H. Goo, Matthew A. Ciorba, Misty Good, Usama Ismail, Kelli L. VanDussen, Vered Gazit, Deborah C. Rubin, Elzbieta A. Swietlicki, Mahama A. Traore, Cliff J. Luke, J. Mark Meacham, Thaddeus S. Stappenbeck, Steven C. George, David M. Alvarado, Brad W. Warner, Adam Bajinting, Wyatt E. Lanik, Jocelyn Ou, Kristen M. Seiler, Jun Guo
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
The development and physiologic role of small intestine (SI) vasculature is poorly studied. This is partly due to a lack of targetable, organ-specific markers for in vivo studies of two critical tissue components: endothelium and stroma. This challen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::091499b98dece0a7612020cca19873c2
http://europepmc.org/articles/PMC7051952
http://europepmc.org/articles/PMC7051952
Autor:
Wesley Hollomon, Gina Hyun, Noor Al-Hammadi, Rhonda Porche-Sorbet, Amir K. Jaffer, Juan Li, Charles S. Eby, Victor G. Davila-Roman, Anna M. Thompson, Brian F. Gage, Lynnae Napoli, Brandi De Vore Whipple, J. Philip Miller, Jeffrey L. Anderson, Robert L. Barrack, Robert C. Pendleton, Ryan M. Nunley, Gerard Moskowitz, Kerri Merritt, Tomás Rodriguez, Gwendolyn A. McMillin, Anne R. Bass, H. Lin, Scott C. Woller, Scott M. Stevens, Cristi R. King
Importance The optimal international normalized ratio (INR) to prevent venous thromboembolism (VTE) in warfarin-treated patients with recent arthroplasty is unknown. Objective To determine the safety and efficacy of a target INR of 1.8 vs 2.5 for VTE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f096776e47f2c7e97301a6b53f933338
https://europepmc.org/articles/PMC6724181/
https://europepmc.org/articles/PMC6724181/
Autor:
Cristi R. King, Karen L. Christman, Nick Joseph Merna, Kelsey Michiko Fung, Steven C. George, Kirk C. Hansen, Jean J. Wang
Publikováno v:
Tissue Engineering Part A. 21:2195-2205
Extracellular matrix (ECM) derived from whole organ decellularization has been successfully used in a variety of tissue engineering applications. ECM contains a complex mixture of functional and structural molecules that are ideally suited for the ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dc5d210efa7be68282c6b48a236c668
https://doi.org/10.1089/ten.tea.2014.0337
https://doi.org/10.1089/ten.tea.2014.0337
Autor:
Jane Y Revollo, Robert H. Gilman, Derek J. Van Booven, Cristi R. King, Sharon Marsh, Howard L. McLeod
Publikováno v:
Pharmacogenomics. 16:441-448
Background: Clinically relevant polymorphisms often demonstrate population-specific allele frequencies. Central and South America remain largely uncategorized in the context of pharmacogenomics. Materials & methods: We assessed 15 polymorphisms from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f899c94095bf7d1a2125d0980e7a0c8b
https://doi.org/10.2217/pgs.15.10
https://doi.org/10.2217/pgs.15.10
Autor:
Ramesh K. Ramanathan, Sharon Marsh, Roscoe F. Morton, Stephen K. Williamson, Erin M. Green, Daniel J. Sargent, Stephen N. Thibodeau, Charles S. Fuchs, Richard M. Goldberg, B. Findlay, Axel Grothey, Howard L. McLeod, Cristi R. King
Publikováno v:
Journal of Clinical Oncology. 28:3227-3233
Purpose With three available chemotherapy drugs for advanced colorectal cancer (CRC), response rate (RR) and survival outcomes have improved with associated morbidity, accentuating the need for tools to select optimal individualized treatment. Pharma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f09bc1cc6aa9c4f3a6fcb7c661535d3
https://doi.org/10.1200/jco.2009.21.7943
https://doi.org/10.1200/jco.2009.21.7943
Autor:
Daniel C. Koboldt, Charles S. Eby, Paul E. Milligan, Howard L. McLeod, R D Miller, Gloria R. Grice, P A Lenzini, M Crankshaw, Paul M. Ridker, Brian F. Gage, Rhonda Porche-Sorbet, Larisa H. Cavallari, Shitalben R. Patel, Elena Deych, Cristi R. King, Deepak Voora
Publikováno v:
Clinical Pharmacology & Therapeutics. 87:445-451
Warfarin demonstrates a wide interindividual variability in response that is mediated partly by variants in cytochrome P450 2C9 (CYP2C9) and vitamin K 2,3-epoxide reductase complex subunit 1 (VKORC1). It is not known whether variants in calumenin (CA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b356491074cd4bba55d6c6fcf6a491c2
https://doi.org/10.1038/clpt.2009.291
https://doi.org/10.1038/clpt.2009.291
Autor:
Brian F. Gage, Elena Deych, Charles S. Eby, Paul M. Ridker, Rhonda Porche-Sorbet, Paul E. Milligan, Gloria R. Grice, Petra A. Lenzini, Cristi R. King
Publikováno v:
Thrombosis and Haemostasis. 104:750-754
SummaryVia generation of vitamin K-dependent proteins, gamma-glutamyl carboxylase (GGCX) plays a critical role in the vitamin K cycle. Single nucleotide polymorphisms (SNPs) in GGCX, therefore, may affect dosing of the vitamin K antagonist, warfarin.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::396a6baa51a03923755dbb4f9bbc8692
https://doi.org/10.1160/th09-11-0763
https://doi.org/10.1160/th09-11-0763
Autor:
Cristi R. King, Rhonda Porche-Sorbet, Paul M. Ridker, Brian F. Gage, Yannick Renaud, Michael S. Phillips, Charles S. Eby
Publikováno v:
American Journal of Clinical Pathology. 129:876-883
Initiation of warfarin therapy is associated with bleeding owing to its narrow therapeutic window and unpredictable therapeutic dose. Pharmacogenetic-based dosing algorithms can improve accuracy of initial warfarin dosing but require rapid genotyping
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5637462ed8509366d766aa69615ca6ed
https://doi.org/10.1309/1e34uapr06pj6hml
https://doi.org/10.1309/1e34uapr06pj6hml
Publikováno v:
Journal of Clinical Oncology. 25:4528-4535
Purpose Standard therapy for advanced ovarian cancer consists of a platinum agent in combination with a taxane, which has a 5-year survival rate of approximately 45%. The large individual variability for ovarian cancer patients in both outcome and to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05701b8241c009f875aee6e76abc1af5
https://doi.org/10.1200/jco.2006.10.4752
https://doi.org/10.1200/jco.2006.10.4752