Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Cristián A. Amador"'
Autor:
Patricio Araos, Cristián A. Amador
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
In recent studies, primary aldosteronism (PA) has been reported as the most common etiology for secondary hypertension of endocrine origin, accounting for approximately 10% of cases. In PA, excess aldosterone production can lead to deleterious effect
Externí odkaz:
https://doaj.org/article/45a36e734973456986ea0f3e63c53fbe
Autor:
Stefanny M. Figueroa, Jean-Philippe Bertocchio, Toshifumi Nakamura, Soumaya El-Moghrabi, Frédéric Jaisser, Cristián A. Amador
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1373 (2023)
Tacrolimus (Tac) is a calcineurin inhibitor commonly used as an immunosuppressor after solid organ transplantation. However, Tac may induce hypertension, nephrotoxicity, and an increase in aldosterone levels. The activation of the mineralocorticoid r
Externí odkaz:
https://doaj.org/article/0d9097bf70344c53b4062546d60771f3
Autor:
Aarón Guerrero, Bruna Visniauskas, Pilar Cárdenas, Stefanny M. Figueroa, Jorge Vivanco, Nicolas Salinas-Parra, Patricio Araos, Quynh My Nguyen, Modar Kassan, Cristián A. Amador, Minolfa C. Prieto, Alexis A. Gonzalez
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Diabetes mellitus (DM) causes high glucose (HG) levels in the plasma and urine. The (pro)renin receptor (PRR) is a key regulator of renal Na+ handling. PRR is expressed in intercalated (IC) cells of the collecting duct (CD) and binds renin to promote
Externí odkaz:
https://doaj.org/article/8b6d87c9c741445a88e2feac0178c38e
Autor:
Stefanny M. Figueroa, Mauricio Lozano, Carolina Lobos, Matthew T. Hennrikus, Alexis A. Gonzalez, Cristián A. Amador
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Chronic kidney disease (CKD) is characterized by renal dysfunction, which is a common feature of other major diseases, such as hypertension and diabetes. Unilateral ureteral obstruction (UUO) has been used as a model of CKD in experimental animals an
Externí odkaz:
https://doaj.org/article/8a9aed299bc84183ac2f987851132ff5
Autor:
Stefanny M. Figueroa, Patricio Araos, Javier Reyes, Basile Gravez, Jonatan Barrera-Chimal, Cristián A. Amador
Publikováno v:
Antioxidants, Vol 10, Iss 3, p 404 (2021)
Renal diseases are a global health concern, and nearly 24% of kidney disease patients are overweight or obese. Particularly, increased body mass index has been correlated with oxidative stress and urinary albumin excretion in kidney disease patients,
Externí odkaz:
https://doaj.org/article/27c060f0186340929ecd2d2155a797f1
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 22, p 8536 (2020)
It is well accepted that the immune system and some cells from adaptive and innate immunity are necessary for the initiation/perpetuation of arterial hypertension (AH). However, whether neutrophils are part of this group remains debatable. There is e
Externí odkaz:
https://doaj.org/article/739383e15b2545f4873ef4b6138e45ca
Autor:
Sebastián Vejar, Ignacio S. Pizarro, Raúl Pulgar-Sepúlveda, Sinay C. Vicencio, Andrés Polit, Cristian A. Amador, Rodrigo del Rio, Rodrigo Varas, Juan A. Orellana, Fernando C. Ortiz
Publikováno v:
Biological Research, Vol 57, Iss 1, Pp 1-14 (2024)
Abstract Background Multiple sclerosis (MS) is an irreversible progressive CNS pathology characterized by the loss of myelin (i.e. demyelination). The lack of myelin is followed by a progressive neurodegeneration triggering symptoms as diverse as fat
Externí odkaz:
https://doaj.org/article/353a3b31af5c426a83235637e2a8a6cd
Publikováno v:
Hypertension. 78
Immune cells play a major role in the development and progression of hypertension. Previous studies have shown that antigen presenting cells (APCs), such as macrophages (Mø) and dendritic cells (DCs) are particularly abundant in kidney. However, the
Autor:
Jorge Vivanco, Cristián A. Amador, Alexis A. Gonzalez, Pilar Cárdenas, Quynh My Nguyen, Bruna Visniauskas, Stefanny M. Figueroa, Nicolas Salinas-Parra, Patricio Araos, Minolfa C. Prieto, Modar Kassan, Aaron Guerrero
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Diabetes mellitus (DM) causes high glucose (HG) levels in the plasma and urine. The (pro)renin receptor (PRR) is a key regulator of renal Na+ handling. PRR is expressed in intercalated (IC) cells of the collecting duct (CD) and binds renin to promote
Autor:
Tak W. Mak, Rodrigo Pacheco, Luis Michea, Alexandra Espinoza, Thorsten Berger, Frederic Jaisser, Cristián A. Amador, Carolina Prado, Stefanny M. Figueroa, Mauricio Lozano, Patricio Araos
Publikováno v:
Journal of Hypertension. 37:1482-1492
Background:Adaptive immunity is crucial in cardiovascular and renal inflammation/fibrosis upon hyperactivation of mineralocorticoid receptor. We have previously demonstrated that dendritic cells can respond to mineralocorticoid receptor activation, a