Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Cristelle Hugo"'
Autor:
Theodoros Kelesidis, Madhav Sharma, Anton Petcherski, Cristelle Hugo, Ellen O’Connor, Nan W Hultgren, Eleni Ritou, David S Williams, Orian S Shirihai, Srinivasa T Reddy
Publikováno v:
Virulence, Vol 12, Iss 1, Pp 2214-2227 (2021)
An oral antiviral against SARS-CoV-2 that also attenuates inflammatory instigators of severe COVID-19 is not available to date. Herein, we show that the apoA-I mimetic peptide 4 F inhibits Spike mediated viral entry and has antiviral activity against
Externí odkaz:
https://doaj.org/article/aa82a508b0e74e76bf0911da79c36a6c
Autor:
Sihyeong Song, Sandro Satta, Madhav B Sharma, Cristelle Hugo, Athanassios Kossyvakis, Shubhendu Sen Roy, Theodoros Kelesidis
Publikováno v:
The Journal of Infectious Diseases.
No treatment exists for mitochondrial dysfunction, a contributor to end-organ disease in human immunodeficiency virus (HIV). The mitochondrial antioxidant mitoquinone mesylate (MitoQ) attenuates mitochondrial dysfunction in preclinical mouse models o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edfd6ba5f08ac445dbaa2d465cb550f2
https://doi.org/10.1093/infdis/jiad044
https://doi.org/10.1093/infdis/jiad044
Mitoquinone mesylate attenuates brain inflammation in humanized mouse model of chronic HIV infection
Autor:
Sandro Satta, Cristelle Hugo, Madhav Sharma, Valerie Rezek, Athanassios Kossyvakis, Shubhendu Sen Roy, Scott Kitchen, Theodoros Kelesidis
Publikováno v:
AIDS. 36:1609-1611
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8888160e4f6dfc90c1d23a0c2e90681
https://doi.org/10.1097/qad.0000000000003291
https://doi.org/10.1097/qad.0000000000003291
Autor:
Anton Petcherski, Madhav Sharma, Sandro Satta, Maria Daskou, Hariclea Vasilopoulos, Cristelle Hugo, Eleni Ritou, Barbara Jane Dillon, Eileen Fung, Gustavo Garcia, Claudio Scafoglio, Arunima Purkayastha, Brigitte N Gomperts, Gregory A Fishbein, Vaithilingaraja Arumugaswami, Marc Liesa, Orian S Shirihai, Theodoros Kelesidis
Publikováno v:
bioRxiv
SummaryTo date, there is no effective oral antiviral against SARS-CoV-2 that is also anti-inflammatory. Herein, we show that the mitochondrial antioxidant mitoquinone/mitoquinol mesylate (Mito-MES), a dietary supplement, has potent antiviral activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f110fd2e0046081e1a6b4594fdac7dd
https://pubmed.ncbi.nlm.nih.gov/35233569
https://pubmed.ncbi.nlm.nih.gov/35233569
Autor:
Kelesidis T; Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA., Madhav S; Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA., Petcherski A; Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA., Cristelle H; Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA., O'Connor E; Molecular Toxicology Interdepartmental Degree Program, University of California Los Angeles, United States., Hultgren NW; Department of Ophthalmology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA., Ritou E; Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA., Williams DS; Department of Ophthalmology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA., Shirihai OS; Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA., Reddy ST; Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA.; Molecular Toxicology Interdepartmental Degree Program, University of California Los Angeles, United States.; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, California, USA.
Publikováno v:
Virulence [Virulence] 2021 Dec; Vol. 12 (1), pp. 2214-2227.