Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Cristan A, Farmer"'
Autor:
Ruin Moaddel, Cristan A. Farmer, Mani Yavi, Bashkim Kadriu, Min Zhu, Jinshui Fan, Qinghua Chen, Elin Lehrmann, Giovanna Fantoni, Supriyo De, Caio H. Mazucanti, Elia E. Acevedo-Diaz, Peixiong Yuan, Todd D. Gould, Lawrence T. Park, Josephine M. Egan, Luigi Ferrucci, Carlos A. Zarate, Jr.
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108527- (2023)
Summary: Ketamine is a treatment for both refractory depression and chronic pain syndromes. In order to explore ketamine’s potential mechanism of action and whether ketamine or its metabolites cross the blood brain barrier, we examined the pharmaco
Externí odkaz:
https://doaj.org/article/dd7ad1b3a925423d97ebe742d4f5433a
Autor:
Ruin Moaddel, Panos Zanos, Cristan A. Farmer, Bashkim Kadriu, Patrick J. Morris, Jacqueline Lovett, Elia E. Acevedo-Diaz, Grace W. Cavanaugh, Peixiong Yuan, Mani Yavi, Craig J. Thomas, Lawrence T. Park, Luigi Ferrucci, Todd D. Gould, Carlos A. Zarate
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Subanesthetic-dose racemic (R,S)-ketamine (ketamine) produces rapid, robust, and sustained antidepressant effects in major depressive disorder (MDD) and bipolar disorder (BD) and has also been shown to effectively treat neuropathic pain, com
Externí odkaz:
https://doaj.org/article/a822b41b1e6245a389bcef25692869af
The contribution of platelets to peripheral BDNF elevation in children with autism spectrum disorder
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-6 (2021)
Abstract Brain-derived neurotrophic factor (BDNF), a key peptide in neurocognitive development, has been reported to be elevated in the serum of children with autism spectrum disorder (ASD). In a few studies, however, no differences or the converse h
Externí odkaz:
https://doaj.org/article/b30d12340fc9469184346d72304286de
Autor:
Jaclyn N Highland, Cristan A Farmer, Panos Zanos, Jacqueline Lovett, Carlos A Zarate, Ruin Moaddel, Todd D Gould
Publikováno v:
J Psychopharmacol
Background: Ketamine is rapidly metabolized to norketamine and hydroxynorketamine (HNK) metabolites. In female mice, when compared to males, higher levels of ( 2R,6R;2S,6S)-HNK have been observed following ketamine treatment, and higher levels of ( 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0089288bb9434a390154bfbcd5ce9530
https://doi.org/10.1177/02698811211064922
https://doi.org/10.1177/02698811211064922
Autor:
An N. Dang Do, Audrey E. Thurm, Cristan A. Farmer, Ariane G. Soldatos, Colby E. Chlebowski, Julie K. O'Reilly, Forbes D. Porter
Publikováno v:
Am J Med Genet A
Progressive vision loss and neurocognitive impairment are early and frequent presentations in CLN3 disease. This highlights neurodevelopmental functioning as critical to the disease, but limits the neuropsychological test repertoire. We evaluated the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb410ff45c210e0fb4158eba352dc1b
https://doi.org/10.1002/ajmg.a.62607
https://doi.org/10.1002/ajmg.a.62607
Autor:
An N. Dang Do, Eva H. Baker, Cristan A. Farmer, Ariane G. Soldatos, Audrey E. Thurm, Forbes D. Porter
Publikováno v:
Molecular Genetics and Metabolism. 139:107584
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90d31d44986c7105b4864f8976e1cd3c
https://doi.org/10.1016/j.ymgme.2023.107584
https://doi.org/10.1016/j.ymgme.2023.107584
Autor:
Ruin Moaddel, Panos Zanos, Cristan A. Farmer, Bashkim Kadriu, Patrick J. Morris, Jacqueline Lovett, Elia E. Acevedo-Diaz, Grace W. Cavanaugh, Peixiong Yuan, Mani Yavi, Craig J. Thomas, Lawrence T. Park, Luigi Ferrucci, Todd D. Gould, Carlos A. Zarate
Publikováno v:
Translational psychiatry. 12(1)
Subanesthetic-dose racemic (R,S)-ketamine (ketamine) produces rapid, robust, and sustained antidepressant effects in major depressive disorder (MDD) and bipolar disorder (BD) and has also been shown to effectively treat neuropathic pain, complex regi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a17bc3b4aaf79ba9c4b6a4e582498302
https://pubmed.ncbi.nlm.nih.gov/35501309
https://pubmed.ncbi.nlm.nih.gov/35501309
Autor:
Nadia S. Hejazi, Cristan A. Farmer, Mark Oppenheimer, Tolulope B. Falodun, Lawrence T. Park, Wallace C. Duncan, Carlos A. Zarate
Publikováno v:
J Psychiatr Res
The Hamilton Depression Rating Scale (HDRS), which includes several insomnia-related items, is potentially valuable in evaluating both depressive and sleep symptoms. However, the HDRS insomnia items have not been fully assessed by objective measures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3e677f0335a037f94863363f7317046
https://pubmed.ncbi.nlm.nih.gov/35092868
https://pubmed.ncbi.nlm.nih.gov/35092868
Autor:
Elizabeth D. Ballard, Cristan A. Farmer, Jessica Gerner, Bartholt Bloomfield-Clagett, Lawrence T. Park, Carlos A. Zarate
Publikováno v:
J Affect Disord
BACKGROUND: Early markers preceding suicide ideation (SI) may provide valuable information for both assessment and treatment. The glutamatergic modulator ketamine has rapid, transient effects on SI, creating an opportunity to observe potential antece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bce2f68baba8520b5a61c3dfb517e95a
https://pubmed.ncbi.nlm.nih.gov/35429526
https://pubmed.ncbi.nlm.nih.gov/35429526
Autor:
Cristan A, Farmer, Jessica R, Gilbert, Ruin, Moaddel, Jomy, George, Lilian, Adeojo, Jacqueline, Lovett, Allison C, Nugent, Bashkim, Kadriu, Peixiong, Yuan, Todd D, Gould, Lawrence T, Park, Carlos A, Zarate
Publikováno v:
Neuropsychopharmacology
A single, subanesthetic dose of (R,S)-ketamine (ketamine) exerts rapid and robust antidepressant effects. Several groups previously reported that (2S,6S;2R,6R)-hydroxynorketamine (HNK) had antidepressant effects in rodents, and that (2R,6R)-HNK incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::401cd2cf6a1fc693aced6a3261d041b5
https://pubmed.ncbi.nlm.nih.gov/32376872
https://pubmed.ncbi.nlm.nih.gov/32376872