Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Crista Thompson"'
Publikováno v:
Mutagenesis. 20:345-350
Biological materials can release amino acids during the course of bacterial mutation testing. Low levels of released amino acids from soluble materials can cause moderate increases in the number of revertant colonies on the plate, whereas higher leve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75f98997db68fa68e4f48ad0e1a2bd75
https://doi.org/10.1093/mutage/gei045
https://doi.org/10.1093/mutage/gei045
Publikováno v:
Environmental and Molecular Mutagenesis. 44:441-447
There is widespread dietary exposure to capsaicin in the form of chili peppers, while capsaicin's analgesic qualities have led to increased use of a topical herbal remedy in various impure forms. Most recently, injection of pure capsaicin has been pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::332c694e6382f8a478c002c4094c3572
https://doi.org/10.1002/em.20072
https://doi.org/10.1002/em.20072
Autor:
Marie-Christine Guiot, Sidong Huang, Hong Zhao, Nicholas Bertos, Monica A. Naujokas, Mathieu Gigoux, Andrea Z. Lai, Michael Hallett, Victoria Marcus, Ali Tofigh, Crista Thompson, Emily Bell, Lorenzo E. Ferri, Rushika Perera, Bita Sehat, Anie Monast, Brent D. G. Page, Morag Park, Sean Cory, Patrick T. Gunning
Publikováno v:
Science signaling. 7(322)
The Met receptor tyrosine kinase is activated or genetically amplified in some gastric cancers, but resistance to small-molecule inhibitors of Met often emerges in patients. We found that Met abundance correlated with a proliferation marker in patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1941794ca82a9ccbf57283b8672b925
https://pubmed.ncbi.nlm.nih.gov/24757178
https://pubmed.ncbi.nlm.nih.gov/24757178
Autor:
Mathieu Gigoux, Michael Hallett, Margarita Souleimanova, Crista Thompson, Hong Zhao, Nicholas Bertos, Tina Gruosso, Sadiq M. Saleh, Morag Park
Publikováno v:
Cancer Research. 76:720-720
Breast cancer is a heterogeneous disease in terms of presentation, morphology, molecular profile and response to therapy. Gene expression profiling has identified intrinsic molecular subtypes that are associated with clinical markers (ER, PR, HER2) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59d50d8a7cdb9776183bb371685a5cf6
https://doi.org/10.1158/1538-7445.am2016-720
https://doi.org/10.1158/1538-7445.am2016-720
Publikováno v:
Molecular Cancer, Vol 10, Iss 1, p 62 (2011)
Molecular Cancer
Molecular Cancer
Background BRCA1 has recently been identified as a potential regulator of mammary stem/progenitor cell differentiation, and this function may explain the high prevalence of breast cancer in BRCA1 mutation carriers, as well as the downregulation of BR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9848805c576cb64a754f601c3fa7e7aa
http://www.molecular-cancer.com/content/10/1/62
http://www.molecular-cancer.com/content/10/1/62
Autor:
Michael Hallett, Atilla Omeroglu, Sarkis Meterissian, Hong Zhao, Tina Gruosso, Nicholas Bertos, Robert Lesurf, Margarita Souleimanova, Greg Finak, Sadiq M. Saleh, Morag Park, Crista Thompson
Publikováno v:
Cancer Research. 75:P4-04
A major challenge in cancer treatment is the heterogeneous nature of the disease. This is particularly evident in breast cancer where gene expression profiling of whole tumours has identified multiple intrinsic subtypes of breast cancer. These subtyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cafbfe8cdd1620d3cec0d3e091f17231
https://doi.org/10.1158/1538-7445.sabcs14-p4-04-01
https://doi.org/10.1158/1538-7445.sabcs14-p4-04-01
Publikováno v:
FEMS microbiology letters. 218(1)
The yeast two-hybrid system was used to identify peptide inhibitors of exotoxin A of Pseudomonas aeruginosa with the goal of using these to design peptide-based drugs against the toxin. A random peptide library consisting of 10(7) peptides ranging in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a7ad250d8ff35d0d993db5828e24efb
https://pubmed.ncbi.nlm.nih.gov/12583902
https://pubmed.ncbi.nlm.nih.gov/12583902
Autor:
Michael Hallett, Hong Zhao, Ali Tofigh, Crista Thompson, Emily Bell, Morag Park, Lorenzo E. Ferri, Nicholas Bertos, Sean Cory, Marie-Christine Guiot, Andrea Z. Lai, Bita Sehat
Publikováno v:
Molecular Cancer Therapeutics. 12:B69-B69
The Met receptor tyrosine kinase activates multiple signalling pathways in response to stimulation by ligand. However, the signalling events that occur under chronic Met activation in cancer cells are poorly understood. Utilizing a pharmacological sm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f2e268f9001ef45a70be7125edb5c9a
https://doi.org/10.1158/1535-7163.targ-13-b69
https://doi.org/10.1158/1535-7163.targ-13-b69
Autor:
Crista Thompson, Naila Chughtai, Andrea Z. Lai, Hong Zhao, Morag Park, Sean Cory, Michael Hallett
Publikováno v:
Cancer Research. 73:967-967
Signaling by the Met, hepatocyte growth factor (HGF) receptor tyrosine kinase (RTK) activates multiple downstream signaling pathways that promote cell migration and invasive growth. Cells that overexpress and are “addicted” to Met also require Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::128c1da0a26291458fc62c0081ac1c72
https://doi.org/10.1158/1538-7445.am2013-967
https://doi.org/10.1158/1538-7445.am2013-967
Publikováno v:
Environmental & Molecular Mutagenesis; Nov2004, Vol. 44 Issue 5, p441-447, 7p